Affinity DataKi: 6.40nMAssay Description:Positive allosteric modulation of 5-HT2C receptor (unknown origin) assessed as increase in 5-HT-induced displacement of [3H]mesulergine by measuring ...More data for this Ligand-Target Pair
Affinity DataKi: 15nMAssay Description:Agonist activity at 5-HT2CR (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 112nMAssay Description:Agonist activity at 5-HT2AR (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 174nMAssay Description:Agonist activity at 5-HT2BR (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 1.80E+3nMAssay Description:Displacement of [3H]-WIN35428 from recombinant human DAT expressed in HEK cell membranes after 90 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
University of Texas Medical Branch
Curated by ChEMBL
University of Texas Medical Branch
Curated by ChEMBL
Affinity DataKi: 2.50E+3nMAssay Description:Displacement of [3H]-nisoxetine from human NET stably expressed in HEK cell membranes incubated for 90 mins under dark condition by scintillation cou...More data for this Ligand-Target Pair
Affinity DataKi: 4.70E+3nMAssay Description:Displacement of [3H]-N-methylspiperone from recombinant human D3R expressed in HEK cell membranes after 90 mins by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to 5-HT2C (unknown origin) assessed as inhibition of ligand bindingMore data for this Ligand-Target Pair
Affinity DataIC50: 0.100nMAssay Description:Inhibition of human MMP-12More data for this Ligand-Target Pair
Affinity DataIC50: 0.100nMAssay Description:Inhibition of human MMP-12More data for this Ligand-Target Pair
Affinity DataIC50: 0.100nMAssay Description:Inhibition of CXCR1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 0.100nMAssay Description:Inhibition of CXCR2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:Inhibition of human MMP-12More data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:Inhibition of human MMP-12More data for this Ligand-Target Pair
Affinity DataIC50: 0.300nMAssay Description:Inhibition of human MMP-12More data for this Ligand-Target Pair
Affinity DataIC50: 0.400nMAssay Description:Inhibition of human MMP-12More data for this Ligand-Target Pair
Affinity DataIC50: 0.400nMAssay Description:Inhibitory concentration against MMP-13More data for this Ligand-Target Pair
Affinity DataIC50: 0.400nMAssay Description:Inhibition of human MMP-12More data for this Ligand-Target Pair
Affinity DataIC50: 0.400nMAssay Description:Inhibition of human recombinant MMP12More data for this Ligand-Target Pair
Affinity DataIC50: 0.610nMAssay Description:Inhibitory concentration against MMP-13More data for this Ligand-Target Pair
Affinity DataIC50: 0.700nMAssay Description:Inhibition of human MMP-12More data for this Ligand-Target Pair
Affinity DataIC50: 0.900nMpH: 7.5 T: 2°CAssay Description:The assays for human MMP activity were performed by incubating fluorogenic peptide substrate with recombinant human MMP catalytic domain along with v...More data for this Ligand-Target Pair
Affinity DataIC50: 0.910nMAssay Description:Inhibitory concentration against MMP-2More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of human MMP-12More data for this Ligand-Target Pair
Affinity DataIC50: <1nMAssay Description:Inhibition of human MMP-12More data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMpH: 7.5 T: 2°CAssay Description:The assays for human MMP activity were performed by incubating fluorogenic peptide substrate with recombinant human MMP catalytic domain along with v...More data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:The assays for human MMP activity were performed by incubating fluorogenic peptide substrate with recombinant human MMP catalytic domain along with v...More data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Mayo Foundation
Curated by ChEMBL
Mayo Foundation
Curated by ChEMBL
Affinity DataIC50: 1.20nMAssay Description:Compound was evaluated for its ability to displace [3H]mazindol binding from rat striatal membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20nMAssay Description:Inhibition of human MMP-12More data for this Ligand-Target Pair
Affinity DataIC50: 1.20nMAssay Description:Inhibition of human recombinant MMP13More data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:The assays for human MMP activity were performed by incubating fluorogenic peptide substrate with recombinant human MMP catalytic domain along with v...More data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:Inhibition of human recombinant MMP13More data for this Ligand-Target Pair
Affinity DataIC50: 1.40nMAssay Description:Inhibition of human recombinant MMP12More data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Mayo Foundation
Curated by ChEMBL
Mayo Foundation
Curated by ChEMBL
Affinity DataIC50: 1.60nMAssay Description:Compound was evaluated for its ability to displace [3H]mazindol binding from rat striatal membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 1.60nMAssay Description:Inhibition of human MMP-12More data for this Ligand-Target Pair
Affinity DataIC50: 1.80nMAssay Description:Inhibition of human recombinant MMP12More data for this Ligand-Target Pair
Affinity DataIC50: 1.90nMAssay Description:Inhibition of human MMP-12More data for this Ligand-Target Pair
Affinity DataIC50: 1.90nMAssay Description:Inhibitory concentration against MMP-13More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of human MMP-12More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of human recombinant MMP12More data for this Ligand-Target Pair
Affinity DataIC50: 2nMpH: 7.5 T: 2°CAssay Description:The assays for human MMP activity were performed by incubating fluorogenic peptide substrate with recombinant human MMP catalytic domain along with v...More data for this Ligand-Target Pair
Affinity DataIC50: 2.10nMAssay Description:The assays for human MMP activity were performed by incubating fluorogenic peptide substrate with recombinant human MMP catalytic domain along with v...More data for this Ligand-Target Pair
Affinity DataIC50: 2.10nMAssay Description:Inhibitory concentration against MMP-13More data for this Ligand-Target Pair
Affinity DataIC50: 2.10nMpH: 7.5 T: 2°CAssay Description:The assays for human MMP activity were performed by incubating fluorogenic peptide substrate with recombinant human MMP catalytic domain along with v...More data for this Ligand-Target Pair
Affinity DataIC50: 2.20nMAssay Description:Inhibition of human MMP-12More data for this Ligand-Target Pair
Affinity DataIC50: 2.20nMAssay Description:Inhibition of human MMP-12More data for this Ligand-Target Pair
Affinity DataIC50: 2.30nMAssay Description:Inhibitory concentration against MMP-13More data for this Ligand-Target Pair
Affinity DataIC50: 2.30nMAssay Description:Inhibition of human MMP-12More data for this Ligand-Target Pair
Affinity DataIC50: 2.30nMAssay Description:Inhibitory concentration against MMP-13More data for this Ligand-Target Pair
Affinity DataIC50: 2.40nMAssay Description:Inhibitory concentration against MMP-13More data for this Ligand-Target Pair