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Found 1347 with Last Name = 'altomare' and Initial = 'c'
TargetCoagulation factor X(Homo sapiens (Human))
Consiglio Nazionale Delle Ricerche

Curated by ChEMBL
LigandPNGBDBM50029090(CHEMBL3343301)
Affinity DataKi:  0.0900nMAssay Description:Inhibition of human factor10a assessed as reduction in hydrolysis of chromogenic substrate S-2765 by Cheng-Prusoff equation analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Bos taurus (Bovine))
Consiglio Nazionale Delle Ricerche

Curated by ChEMBL
LigandPNGBDBM50029090(CHEMBL3343301)
Affinity DataKi:  0.0960nMAssay Description:Inhibition of bovine thrombin assessed as reduction in hydrolysis of chromogenic substrate S-2238 by Lineweaver-Burk analysisMore data for this Ligand-Target Pair
TargetCoagulation factor X(Homo sapiens (Human))
Consiglio Nazionale Delle Ricerche

Curated by ChEMBL
LigandPNGBDBM50029091(CHEMBL3343299)
Affinity DataKi:  0.110nMAssay Description:Inhibition of human factor10a assessed as reduction in hydrolysis of chromogenic substrate S-2765 by Lineweaver-Burk analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Consiglio Nazionale Delle Ricerche

Curated by ChEMBL
LigandPNGBDBM50029095(CHEMBL3343300)
Affinity DataKi:  0.25nMAssay Description:Inhibition of human factor10a assessed as reduction in hydrolysis of chromogenic substrate S-2765 by Cheng-Prusoff equation analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Consiglio Nazionale Delle Ricerche

Curated by ChEMBL
LigandPNGBDBM50029091(CHEMBL3343299)
Affinity DataKi:  0.600nMAssay Description:Inhibition of human factor10a assessed as reduction in hydrolysis of chromogenic substrate S-2765 by Cheng-Prusoff equation analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Equus caballus (Horse))
University Of Bari&Quot;A. Moro&Quot

Curated by ChEMBL
LigandPNGBDBM50210854(CHEMBL3960040)
Affinity DataKi:  0.700nMAssay Description:Competitive inhibition of horse serum BChE in presence of varying levels of butyrylthiocholine iodide substrate by Lineweaver-burk plot methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Consiglio Nazionale Delle Ricerche

Curated by ChEMBL
LigandPNGBDBM50029090(CHEMBL3343301)
Affinity DataKi:  0.870nMAssay Description:Inhibition of human factor10a assessed as reduction in hydrolysis of chromogenic substrate S-2765 by Lineweaver-Burk analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Bos taurus (Bovine))
Consiglio Nazionale Delle Ricerche

Curated by ChEMBL
LigandPNGBDBM50442068(CHEMBL2441057)
Affinity DataKi:  6nMAssay Description:Inhibition of bovine thrombin using D-Phe-Pip-Arg-p-NA as substrate by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Bos taurus (Bovine))
Consiglio Nazionale Delle Ricerche

Curated by ChEMBL
LigandPNGBDBM50442068(CHEMBL2441057)
Affinity DataKi:  6nMAssay Description:Inhibition of bovine thrombin using D-Phe-Pip-Arg-p-NA as substrate by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM8960((+/-)-2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimet...)
Affinity DataKi:  13nMAssay Description:Mixed type inhibition of human AChE using acetylthiocholineiodide as substrate measured for every 30 sec for 5 mins by Ellman's methodMore data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
University Of Bari "Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50585934(CHEMBL5082824)
Affinity DataKi:  13nMAssay Description:Competitive inhibition of human recombinant MAO-B expressed in supersomes using kynuramine as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Bos taurus (Bovine))
Consiglio Nazionale Delle Ricerche

Curated by ChEMBL
LigandPNGBDBM50029091(CHEMBL3343299)
Affinity DataKi:  18nMAssay Description:Inhibition of bovine thrombin assessed as reduction in hydrolysis of chromogenic substrate S-2238 by Lineweaver-Burk analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50540764(CHEMBL4648322)
Affinity DataKi:  19nMAssay Description:Mixed type inhibition of human AChE using acetylthiocholineiodide as substrate measured for every 30 sec for 5 mins by Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetProthrombin(Bos taurus (Bovine))
Consiglio Nazionale Delle Ricerche

Curated by ChEMBL
LigandPNGBDBM50442069(CHEMBL2441037)
Affinity DataKi:  31nMAssay Description:Inhibition of bovine thrombin using D-Phe-Pip-Arg-p-NA as substrate by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Bos taurus (Bovine))
Consiglio Nazionale Delle Ricerche

Curated by ChEMBL
LigandPNGBDBM50442073(CHEMBL2441035)
Affinity DataKi:  53nMAssay Description:Inhibition of bovine thrombin using D-Phe-Pip-Arg-p-NA as substrate by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Consiglio Nazionale Delle Ricerche

Curated by ChEMBL
LigandPNGBDBM50292901(CHEMBL454373 | N-(3-((4'-(trifluoromethyl)biphenyl...)
Affinity DataKi:  57nMAssay Description:Inhibition of human factor 10a by amydolitic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Bos taurus (Bovine))
Consiglio Nazionale Delle Ricerche

Curated by ChEMBL
LigandPNGBDBM50442070(CHEMBL2441054)
Affinity DataKi:  63nMAssay Description:Inhibition of bovine thrombin using D-Phe-Pip-Arg-p-NA as substrate by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Bos taurus (Bovine))
Consiglio Nazionale Delle Ricerche

Curated by ChEMBL
LigandPNGBDBM50442071(CHEMBL2441055)
Affinity DataKi:  64nMAssay Description:Inhibition of bovine thrombin using D-Phe-Pip-Arg-p-NA as substrate by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Universit£

Curated by ChEMBL
LigandPNGBDBM50093085(CHEMBL3586582)
Affinity DataKi:  80nMAssay Description:Mixed type inhibition of electric eel AChE by Lineweaver-Burk plotMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Bos taurus (Bovine))
Consiglio Nazionale Delle Ricerche

Curated by ChEMBL
LigandPNGBDBM50442074(CHEMBL2441036)
Affinity DataKi:  83nMAssay Description:Inhibition of bovine thrombin using D-Phe-Pip-Arg-p-NA as substrate by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50424045(CHEMBL2314726)
Affinity DataKi:  93nMAssay Description:Mixed type inhibition of human AChE using acetylthiocholineiodide as substrate measured for every 30 sec for 5 mins by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50424045(CHEMBL2314726)
Affinity DataKi:  93.4nMAssay Description:Mixed type inhibition of human AChE using acetylthiocholineiodide as substrate measured for every 30 sec for 5 mins by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Equus caballus (Horse))
University Of Bari&Quot;A. Moro&Quot

Curated by ChEMBL
LigandPNGBDBM50524749(CHEMBL4538834)
Affinity DataKi:  98nMAssay Description:Mixed type inhibition of equine serum BChE assessed as Ki using butyrylthiocholine as substrate preincubated for 20 mins followed by substrate additi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProthrombin(Bos taurus (Bovine))
Consiglio Nazionale Delle Ricerche

Curated by ChEMBL
LigandPNGBDBM50029090(CHEMBL3343301)
Affinity DataKi:  100nMAssay Description:Inhibition of bovine thrombin assessed as reduction in hydrolysis of chromogenic substrate S-2238 by Cheng-Prusoff equation analysisMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Universit£

Curated by ChEMBL
LigandPNGBDBM50093227(CHEMBL3586608)
Affinity DataKi:  100nMAssay Description:Mixed type inhibition of electric eel AChE by Lineweaver-Burk plotMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Bos taurus (Bovine))
Consiglio Nazionale Delle Ricerche

Curated by ChEMBL
LigandPNGBDBM50442075(CHEMBL2441047)
Affinity DataKi:  124nMAssay Description:Inhibition of bovine thrombin using D-Phe-Pip-Arg-p-NA as substrate by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Consiglio Nazionale Delle Ricerche

Curated by ChEMBL
LigandPNGBDBM50292898(CHEMBL453387 | N-(3-((3',5'-difluorobiphenyl-4-yl)...)
Affinity DataKi:  130nMAssay Description:Inhibition of human factor 10a by amydolitic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Consiglio Nazionale Delle Ricerche

Curated by ChEMBL
LigandPNGBDBM50442079(CHEMBL2441033)
Affinity DataKi:  133nMAssay Description:Inhibition of human factor 10a using Z-D-Arg-Gly-Arg-p-NA as substrate by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Bos taurus (Bovine))
Consiglio Nazionale Delle Ricerche

Curated by ChEMBL
LigandPNGBDBM50442093(CHEMBL2441053)
Affinity DataKi:  156nMAssay Description:Inhibition of bovine thrombin using D-Phe-Pip-Arg-p-NA as substrate by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Bos taurus (Bovine))
Consiglio Nazionale Delle Ricerche

Curated by ChEMBL
LigandPNGBDBM50029095(CHEMBL3343300)
Affinity DataKi:  160nMAssay Description:Inhibition of bovine thrombin assessed as reduction in hydrolysis of chromogenic substrate S-2238 by Cheng-Prusoff equation analysisMore data for this Ligand-Target Pair
TargetCoagulation factor X(Homo sapiens (Human))
Consiglio Nazionale Delle Ricerche

Curated by ChEMBL
LigandPNGBDBM50292892(CHEMBL490298 | N-{3-[(3'-fluoro-1,1'-biphenyl-4-yl...)
Affinity DataKi:  177nMAssay Description:Inhibition of human factor 10a by amydolitic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Bos taurus (Bovine))
Consiglio Nazionale Delle Ricerche

Curated by ChEMBL
LigandPNGBDBM50442072(CHEMBL2441058)
Affinity DataKi:  211nMAssay Description:Inhibition of bovine thrombin using D-Phe-Pip-Arg-p-NA as substrate by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Bos taurus (Bovine))
Consiglio Nazionale Delle Ricerche

Curated by ChEMBL
LigandPNGBDBM50442094(CHEMBL2441052)
Affinity DataKi:  260nMAssay Description:Inhibition of bovine thrombin using D-Phe-Pip-Arg-p-NA as substrate by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Consiglio Nazionale Delle Ricerche

Curated by ChEMBL
LigandPNGBDBM50292894(CHEMBL490491 | N-(3-((2',4'-difluorobiphenyl-4-yl)...)
Affinity DataKi:  512nMAssay Description:Inhibition of human factor 10a by amydolitic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Consiglio Nazionale Delle Ricerche

Curated by ChEMBL
LigandPNGBDBM50292895(CHEMBL489694 | N-(3-((2',3'-difluorobiphenyl-4-yl)...)
Affinity DataKi:  548nMAssay Description:Inhibition of human factor 10a by amydolitic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Consiglio Nazionale Delle Ricerche

Curated by ChEMBL
LigandPNGBDBM50442069(CHEMBL2441037)
Affinity DataKi:  606nMAssay Description:Inhibition of human factor 10a using Z-D-Arg-Gly-Arg-p-NA as substrate by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Consiglio Nazionale Delle Ricerche

Curated by ChEMBL
LigandPNGBDBM50292900(CHEMBL508488 | N-(3-((3',4',5'-trifluorobiphenyl-4...)
Affinity DataKi:  666nMAssay Description:Inhibition of human factor 10a by amydolitic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Consiglio Nazionale Delle Ricerche

Curated by ChEMBL
LigandPNGBDBM50292893(CHEMBL524125 | N-(3-((2'-fluorobiphenyl-4-yl)metho...)
Affinity DataKi:  767nMAssay Description:Inhibition of human factor 10a by amydolitic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Consiglio Nazionale Delle Ricerche

Curated by ChEMBL
LigandPNGBDBM50442078(CHEMBL2441030)
Affinity DataKi:  774nMAssay Description:Inhibition of human factor 10a using Z-D-Arg-Gly-Arg-p-NA as substrate by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Consiglio Nazionale Delle Ricerche

Curated by ChEMBL
LigandPNGBDBM50292887(CHEMBL491672 | N-{[3-(1,1'-biphenyl-4-yl)methoxy]p...)
Affinity DataKi:  1.00E+3nMAssay Description:Inhibition of human factor 10a by amydolitic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Consiglio Nazionale Delle Ricerche

Curated by ChEMBL
LigandPNGBDBM50442072(CHEMBL2441058)
Affinity DataKi:  1.10E+3nMAssay Description:Inhibition of human factor 10a using Z-D-Arg-Gly-Arg-p-NA as substrate by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Bos taurus (Bovine))
Consiglio Nazionale Delle Ricerche

Curated by ChEMBL
LigandPNGBDBM50442081(CHEMBL2441039)
Affinity DataKi:  1.15E+3nMAssay Description:Inhibition of bovine thrombin using D-Phe-Pip-Arg-p-NA as substrate by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Consiglio Nazionale Delle Ricerche

Curated by ChEMBL
LigandPNGBDBM50292896(CHEMBL508759 | N-(3-((2',5'-difluorobiphenyl-4-yl)...)
Affinity DataKi:  1.27E+3nMAssay Description:Inhibition of human factor 10a by amydolitic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Bos taurus (Bovine))
Consiglio Nazionale Delle Ricerche

Curated by ChEMBL
LigandPNGBDBM50442080(CHEMBL2441040)
Affinity DataKi:  1.30E+3nMAssay Description:Inhibition of bovine thrombin using D-Phe-Pip-Arg-p-NA as substrate by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Universit£

Curated by ChEMBL
LigandPNGBDBM50532731(CHEMBL4571763)
Affinity DataKi:  1.37E+3nMAssay Description:Mixed-type inhibition of electric eel AChE using S-acetylthiocholine as substrate preincubated for 20 mins followed by substrate addition measured fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Universit£

Curated by ChEMBL
LigandPNGBDBM50532731(CHEMBL4571763)
Affinity DataKi:  1.37E+3nMAssay Description:Mixed-type inhibition of electric eel AChE using S-acetylthiocholine as substrate preincubated for 20 mins followed by substrate addition measured fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Consiglio Nazionale Delle Ricerche

Curated by ChEMBL
LigandPNGBDBM50292897(CHEMBL455203 | N-(3-((2',6'-difluorobiphenyl-4-yl)...)
Affinity DataKi:  1.45E+3nMAssay Description:Inhibition of human factor 10a by amydolitic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Consiglio Nazionale Delle Ricerche

Curated by ChEMBL
LigandPNGBDBM50292886(CHEMBL491283 | N-(3-(biphenyl-4-ylmethoxy)phenyl)-...)
Affinity DataKi:  2.00E+3nMAssay Description:Inhibition of human factor 10a by amydolitic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50585934(CHEMBL5082824)
Affinity DataKi:  2.00E+3nMAssay Description:Mixed type inhibition of human AChE by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Bos taurus (Bovine))
Consiglio Nazionale Delle Ricerche

Curated by ChEMBL
LigandPNGBDBM50442092(CHEMBL2441051)
Affinity DataKi:  2.03E+3nMAssay Description:Inhibition of bovine thrombin using D-Phe-Pip-Arg-p-NA as substrate by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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