Affinity DataIC50: 0.0800nMpH: 7.4 T: 2°CAssay Description:The enzyme was assayed in DELFIA format using purified FLAG-TOR in kinase buffer containing ATP and His6-S6K in the presence of inhibitor compounds. ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.100nMAssay Description:Inhibition of N-terminal GST tagged recombinant human EGFR L858R/T790M (669 to end residues) double mutant expressed in baculovirus infected Sf9 inse...More data for this Ligand-Target Pair
Affinity DataIC50: 0.100nMAssay Description:Inhibition of human mTOR (1360-2549 amino acids) expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.110nMAssay Description:Inhibition of Flag-tagged human mTOR by DELFIA methodMore data for this Ligand-Target Pair
Affinity DataIC50: 0.160nMAssay Description:Inhibition of Flag-tagged human mTOR by DELFIA methodMore data for this Ligand-Target Pair
Affinity DataIC50: 0.170nMAssay Description:Inhibition of Flag-tagged human mTOR by DELFIA methodMore data for this Ligand-Target Pair
Affinity DataIC50: 0.190nMAssay Description:Inhibition of Flag-tagged human mTOR by DELFIA methodMore data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:Inhibition of mTOR in HEK293 cells by DELFIA assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:Inhibition of Flag-tagged human mTOR by DELFIA methodMore data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:Inhibition of Flag-tagged human mTOR by DELFIA methodMore data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMpH: 7.4 T: 2°CAssay Description:The enzyme was assayed in DELFIA format using purified FLAG-TOR in kinase buffer containing ATP and His6-S6K in the presence of inhibitor compounds. ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:Inhibition of N-terminal GST tagged recombinant human EGFR L858R/T790M (669 to end residues) double mutant expressed in baculovirus infected Sf9 inse...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Inhibition of human PI3Kalpha expressed in SF9 insect cells after 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:Inhibition of human mTOR (1360-2549 amino acids) expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:Inhibition of N-terminal GST tagged recombinant human EGFR L858R/T790M (669 to end residues) double mutant expressed in baculovirus infected Sf9 inse...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:Inhibition of Flag-tagged human mTOR by DELFIA methodMore data for this Ligand-Target Pair
Affinity DataIC50: 0.220nMAssay Description:Inhibition of Flag-tagged human mTOR by DELFIA methodMore data for this Ligand-Target Pair
Affinity DataIC50: 0.220nMAssay Description:Inhibition of Flag-tagged human mTOR by DELFIA methodMore data for this Ligand-Target Pair
Affinity DataIC50: 0.230nMAssay Description:Inhibition of Flag-tagged human mTOR by DELFIA methodMore data for this Ligand-Target Pair
Affinity DataIC50: 0.230nMAssay Description:Inhibition of Flag-tagged human mTOR by DELFIA methodMore data for this Ligand-Target Pair
Affinity DataIC50: 0.280nMAssay Description:Inhibition of Flag-tagged human mTOR by DELFIA methodMore data for this Ligand-Target Pair
Affinity DataIC50: 0.300nMAssay Description:Inhibition of N-terminal GST tagged recombinant human EGFR L858R/T790M (669 to end residues) double mutant expressed in baculovirus infected Sf9 inse...More data for this Ligand-Target Pair
Affinity DataIC50: 0.300nMAssay Description:Inhibition of N-terminal GST tagged recombinant human EGFR L858R/T790M (669 to end residues) double mutant expressed in baculovirus infected Sf9 inse...More data for this Ligand-Target Pair
Affinity DataIC50: 0.300nMAssay Description:Inhibition of human mTOR (1360-2549 amino acids) expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.300nMAssay Description:Inhibition of human mTOR (1360-2549 amino acids) expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.300nMAssay Description:Inhibition of human mTOR (1360-2549 amino acids) expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 0.300nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
Affinity DataIC50: 0.300nMAssay Description:Inhibition of N-terminal GST tagged recombinant human EGFR L858R/T790M (669 to end residues) double mutant expressed in baculovirus infected Sf9 inse...More data for this Ligand-Target Pair
Affinity DataIC50: 0.300nMpH: 7.4 T: 2°CAssay Description:The enzyme was assayed in DELFIA format using purified FLAG-TOR in kinase buffer containing ATP and His6-S6K in the presence of inhibitor compounds. ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.300nMAssay Description:Inhibition of human mTOR (1360-2549 amino acids) expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.310nMAssay Description:Inhibition of mTOR by DELFIAMore data for this Ligand-Target Pair
Affinity DataIC50: 0.320nMpH: 7.4 T: 2°CAssay Description:The enzyme was assayed in DELFIA format using purified FLAG-TOR in kinase buffer containing ATP and His6-S6K in the presence of inhibitor compounds. ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.320nMAssay Description:Inhibition of Flag-tagged human mTOR by DELFIA methodMore data for this Ligand-Target Pair
Affinity DataIC50: 0.320nMAssay Description:Inhibition of mTOR by DELFIAMore data for this Ligand-Target Pair
Affinity DataIC50: 0.340nMpH: 7.4 T: 2°CAssay Description:The enzyme was assayed in DELFIA format using purified FLAG-TOR in kinase buffer containing ATP and His6-S6K in the presence of inhibitor compounds. ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.350nMAssay Description:Inhibition of mTOR by DELFIAMore data for this Ligand-Target Pair
Affinity DataIC50: 0.380nMpH: 7.4 T: 2°CAssay Description:The enzyme was assayed in DELFIA format using purified FLAG-TOR in kinase buffer containing ATP and His6-S6K in the presence of inhibitor compounds. ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.380nMAssay Description:Inhibition of Flag-tagged human mTOR by DELFIA methodMore data for this Ligand-Target Pair
Affinity DataIC50: 0.390nMAssay Description:Inhibition of mTOR by DELFIAMore data for this Ligand-Target Pair
Affinity DataIC50: 0.400nMAssay Description:Inhibition of N-terminal GST tagged recombinant human EGFR L858R/T790M (669 to end residues) double mutant expressed in baculovirus infected Sf9 inse...More data for this Ligand-Target Pair
Affinity DataIC50: 0.400nMAssay Description:Inhibition of human mTOR (1360-2549 amino acids) expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.400nMAssay Description:Inhibition of human mTOR (1360-2549 amino acids) expressed in HEK293 cellsMore data for this Ligand-Target Pair