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Found 370 with Last Name = 'cao' and Initial = 'c'
TargetCytochrome P450 1B1(Homo sapiens (Human))
Hunan Agricultural University

Curated by ChEMBL
LigandPNGBDBM50551090(CHEMBL4748722)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of recombinant human CYP1B1 expressed in baculovirus infected insect cells using 7-ethoxyresorufin as substrate preincubated for 5 mins fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 1B1(Homo sapiens (Human))
Hunan Agricultural University

Curated by ChEMBL
LigandPNGBDBM50081717(CHEMBL3422338)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of recombinant human CYP1B1 expressed in baculovirus infected insect cells using 7-ethoxyresorufin as substrate preincubated for 5 mins fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))TBA
LigandPNGBDBM50252395(CHEMBL4087616)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of human HDAC6More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))TBA
LigandPNGBDBM50421842(CHEMBL5268638)
Affinity DataIC50:  0.730nMAssay Description:Inhibition of HDAC6 (unknown origin) using Fluor de lys as substrate by fluorescence based analysisMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))TBA
LigandPNGBDBM50380387(CHEMBL2018451)
Affinity DataIC50:  1nMAssay Description:Inhibition of human HDAC6More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))TBA
LigandPNGBDBM50608068(CHEMBL5275164)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate measured after 20 mins by by Ellmans methodMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetCytochrome P450 1B1(Homo sapiens (Human))
Hunan Agricultural University

Curated by ChEMBL
LigandPNGBDBM50081709(CHEMBL3422257)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of recombinant human CYP1B1 expressed in baculovirus infected insect cells using 7-ethoxyresorufin as substrate preincubated for 5 mins fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase CSK(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50503098(CHEMBL4582324)
Affinity DataIC50:  2nMAssay Description:Inhibition of CSK (unknown origin) using fluorescent labeled peptide as substrate in presence of ATP at Km concentration by caliper methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 1B1(Homo sapiens (Human))
Hunan Agricultural University

Curated by ChEMBL
LigandPNGBDBM50551091(CHEMBL4792004)
Affinity DataIC50:  2.10nMAssay Description:Inhibition of recombinant human CYP1B1 expressed in baculovirus infected insect cells using 7-ethoxyresorufin as substrate preincubated for 5 mins fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
West China Hospital Of Sichuan University

Curated by ChEMBL
LigandPNGBDBM50553813(CHEMBL4783227)
Affinity DataIC50:  2.30nMAssay Description:Inhibition of recombinant human C-terminal His-tagged PARP1 expressed in Sf9 insect cells preincubated for 20 mins in presence of activated DNA follo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
West China Hospital Of Sichuan University

Curated by ChEMBL
LigandPNGBDBM50553814(CHEMBL4795449)
Affinity DataIC50:  2.60nMAssay Description:Inhibition of recombinant human C-terminal His-tagged PARP1 expressed in Sf9 insect cells preincubated for 20 mins in presence of activated DNA follo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase CSK(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50503095(CHEMBL4577049)
Affinity DataIC50: <3nMAssay Description:Inhibition of His-tagged/GST-tagged CSK (unknown origin) incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase CSK(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50503102(CHEMBL4445994)
Affinity DataIC50: <3nMAssay Description:Inhibition of His-tagged/GST-tagged CSK (unknown origin) incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase CSK(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50503099(CHEMBL4545269)
Affinity DataIC50: <3nMAssay Description:Inhibition of His-tagged/GST-tagged CSK (unknown origin) incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase CSK(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50503098(CHEMBL4582324)
Affinity DataIC50: <3nMAssay Description:Inhibition of His-tagged/GST-tagged CSK (unknown origin) incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3(Homo sapiens (Human))TBA
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  3.10nMAssay Description:Inhibition of HDAC3 (unknown origin) using fluorogenic peptide RHKKAc-AMC as substrate by fluorescence-based assayMore data for this Ligand-Target Pair
In DepthDetails PubMedDrugBank

TargetHistone deacetylase 3(Homo sapiens (Human))TBA
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  3.10nMAssay Description:Inhibition of HDAC3 (unknown origin) using Fluor de lys as substrate by fluorescence based analysisMore data for this Ligand-Target Pair
In DepthDetails PubMedDrugBank

TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
West China Hospital Of Sichuan University

Curated by ChEMBL
LigandPNGBDBM27566(4-({3-[(4-cyclopropanecarbonylpiperazin-1-yl)carbo...)
Affinity DataIC50:  3.40nMAssay Description:Inhibition of recombinant human C-terminal His-tagged PARP1 expressed in Sf9 insect cells preincubated for 20 mins in presence of activated DNA follo...More data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))TBA
LigandPNGBDBM50468316(CHEMBL4280893)
Affinity DataIC50:  3.70nMAssay Description:Inhibition of human HDAC6More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTyrosine-protein kinase CSK(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50503102(CHEMBL4445994)
Affinity DataIC50:  4nMAssay Description:Inhibition of CSK (unknown origin) using fluorescent labeled peptide as substrate in presence of ATP at Km concentration by caliper methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase CSK(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50503095(CHEMBL4577049)
Affinity DataIC50:  4nMAssay Description:Inhibition of CSK (unknown origin) using fluorescent labeled peptide as substrate in presence of ATP at Km concentration by caliper methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase CSK(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50503100(CHEMBL4443654)
Affinity DataIC50:  4nMAssay Description:Inhibition of CSK (unknown origin) using fluorescent labeled peptide as substrate in presence of ATP at Km concentration by caliper methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase CSK(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50503099(CHEMBL4545269)
Affinity DataIC50:  4nMAssay Description:Inhibition of CSK (unknown origin) using fluorescent labeled peptide as substrate in presence of ATP at Km concentration by caliper methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase CSK(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50503106(CHEMBL4537527)
Affinity DataIC50:  4nMAssay Description:Inhibition of His-tagged/GST-tagged CSK (unknown origin) incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 1B1(Homo sapiens (Human))
Hunan Agricultural University

Curated by ChEMBL
LigandPNGBDBM50014323(2-PHENYL-4H-BENZO[H]CHROMEN-4-ONE | 2-Phenyl-benzo...)
Affinity DataIC50:  4.10nMAssay Description:Inhibition of recombinant human CYP1B1 expressed in baculovirus infected insect cells using 7-ethoxyresorufin as substrate preincubated for 5 mins fo...More data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))TBA
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  4.20nMAssay Description:Inhibition of HDAC1 (unknown origin) using fluorogenic peptide RHKKAc-AMC as substrate by fluorescence-based assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))TBA
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  4.20nMAssay Description:Inhibition of HDAC1 (unknown origin) using Fluor de lys as substrate by fluorescence based analysisMore data for this Ligand-Target Pair
TargetAndrogen receptor(Homo sapiens (Human))
Sichuan University And Collaborative Innovation Center For Biotherapy

Curated by ChEMBL
LigandPNGBDBM50367916(METHYLTRIENOLONE | Metribolone | R-1881)
Affinity DataIC50:  4.60nMAssay Description:Competitive displacement of [3H]R1881 from human AR-LBD expressed in LNCaP cells incubated for 24 hrs by scintillation counting method based radiolig...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase CSK(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50503100(CHEMBL4443654)
Affinity DataIC50:  5nMAssay Description:Inhibition of His-tagged/GST-tagged CSK (unknown origin) incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))TBA
LigandPNGBDBM50005711(CHEBI:46024 | GNF-Pf-1011 | TRICHOSTATIN | Trichos...)
Affinity DataIC50:  5.60nMAssay Description:Inhibition of HDAC6 (unknown origin) using Fluor de lys as substrate by fluorescence based analysisMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase CSK(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50503106(CHEMBL4537527)
Affinity DataIC50:  6nMAssay Description:Inhibition of CSK (unknown origin) using fluorescent labeled peptide as substrate in presence of ATP at Km concentration by caliper methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Hunan Agricultural University

Curated by ChEMBL
LigandPNGBDBM50014323(2-PHENYL-4H-BENZO[H]CHROMEN-4-ONE | 2-Phenyl-benzo...)
Affinity DataIC50:  6.60nMAssay Description:Inhibition of recombinant human CYP1A2 expressed in baculovirus infected insect cells using 7-ethoxyresorufin as substrate preincubated for 5 mins fo...More data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))TBA
LigandPNGBDBM50421841(CHEMBL5270958)
Affinity DataIC50:  6.60nMAssay Description:Inhibition of HDAC6 (unknown origin) using Fluor de lys as substrate by fluorescence based analysisMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCytochrome P450 1B1(Homo sapiens (Human))
Hunan Agricultural University

Curated by ChEMBL
LigandPNGBDBM50551094(CHEMBL4757820)
Affinity DataIC50:  7nMAssay Description:Potentiation of amphotericin-induced cytotoxicity against human DU-145 cells over expressing CYP1B1 assessed as reversal of CYP1B1 mediated drug resi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))TBA
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  7.10nMAssay Description:Inhibition of HDAC6 (unknown origin) using fluorogenic peptide RHKKAc-AMC as substrate by fluorescence-based assayMore data for this Ligand-Target Pair
In DepthDetails PubMedDrugBank

TargetHistone deacetylase 6(Homo sapiens (Human))TBA
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  7.10nMAssay Description:Inhibition of HDAC6 (unknown origin) using Fluor de lys as substrate by fluorescence based analysisMore data for this Ligand-Target Pair
In DepthDetails PubMedDrugBank

TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Sichuan University And Collaborative Innovation Center Of Biotherapy

Curated by ChEMBL
LigandPNGBDBM50537765(CHEMBL4642944)
Affinity DataIC50:  7.40nMAssay Description:Inhibition of tracer K10 binding to NanoLuc-CDK2/Cyclin A (unknown origin) expressed in human HEK293 cells after 1 hr in presence of ATP by NanoBRET ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase CSK(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50503107(CHEMBL4437906)
Affinity DataIC50:  8nMAssay Description:Inhibition of His-tagged/GST-tagged CSK (unknown origin) incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50005711(CHEBI:46024 | GNF-Pf-1011 | TRICHOSTATIN | Trichos...)
Affinity DataIC50:  8.40nMAssay Description:Inhibition of HDAC1 (unknown origin) using Fluor de lys as substrate by fluorescence based analysisMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))TBA
LigandPNGBDBM50421817(CHEMBL5273674)
Affinity DataIC50:  8.60nMAssay Description:Inhibition of HDAC6 (unknown origin) using Fluor de lys as substrate by fluorescence based analysisMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))TBA
LigandPNGBDBM50421818(CHEMBL5289315)
Affinity DataIC50:  9.80nMAssay Description:Inhibition of HDAC6 (unknown origin) using Fluor de lys as substrate by fluorescence based analysisMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))TBA
LigandPNGBDBM50421819(CHEMBL5286689)
Affinity DataIC50:  10nMAssay Description:Inhibition of HDAC6 (unknown origin) using Fluor de lys as substrate by fluorescence based analysisMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))TBA
LigandPNGBDBM50421821(CHEMBL5266137)
Affinity DataIC50:  11nMAssay Description:Inhibition of HDAC6 (unknown origin) using Fluor de lys as substrate by fluorescence based analysisMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone deacetylase 2(Homo sapiens (Human))TBA
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  12nMAssay Description:Inhibition of HDAC2 (unknown origin) using fluorogenic peptide RHKKAc-AMC as substrate by fluorescence-based assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 2(Homo sapiens (Human))TBA
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  12nMAssay Description:Inhibition of HDAC2 (unknown origin) using Fluor de lys as substrate by fluorescence based analysisMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM10880(AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)
Affinity DataIC50:  12nMAssay Description:Inhibition of recombinant human CA2 using 4-nitrophenylacetate as substrate by esterase assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))TBA
LigandPNGBDBM50421820(CHEMBL5285323)
Affinity DataIC50:  12nMAssay Description:Inhibition of HDAC6 (unknown origin) using Fluor de lys as substrate by fluorescence based analysisMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetTyrosine-protein kinase CSK(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50503101(CHEMBL4469360)
Affinity DataIC50:  13nMAssay Description:Inhibition of CSK (unknown origin) using fluorescent labeled peptide as substrate in presence of ATP at Km concentration by caliper methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))TBA
LigandPNGBDBM50421822(CHEMBL5282117)
Affinity DataIC50:  14nMAssay Description:Inhibition of HDAC6 (unknown origin) using Fluor de lys as substrate by fluorescence based analysisMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAndrogen receptor(Homo sapiens (Human))
Sichuan University And Collaborative Innovation Center For Biotherapy

Curated by ChEMBL
LigandPNGBDBM8903((1S,2R,10S,11S,14S,15S)-14-acetyl-2,15-dimethyltet...)
Affinity DataIC50:  14nMAssay Description:Competitive displacement of [3H]R1881 from human AR-LBD expressed in LNCaP cells incubated for 24 hrs by scintillation counting method based radiolig...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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