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Found 74 with Last Name = 'chiang' and Initial = 'pk'
TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50011851(2,2-Diphenyl-propionic acid 6-methyl-6-aza-bicyclo...)
Affinity DataKi:  0.270nMAssay Description:Inhibit the binding of [N-mnethyl-3H]-scopolamine [3H]-NMS) to Muscarinic acetylcholine receptor of human IRM-30 neuroblastoma cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50403547(ATROPEN | ATROPINE)
Affinity DataKi:  1nMAssay Description:Inhibit the binding of [N-mnethyl-3H]-scopolamine [3H]-NMS) to Muscarinic acetylcholine receptor of human IRM-30 neuroblastoma cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
Institute of Research

Curated by ChEMBL
LigandPNGBDBM50005681(2-Cyclohexyl-2-phenyl-propionic acid 3-dimethylami...)
Affinity DataKi:  1.5nMAssay Description:Antimuscurinic potency and subset specificity of the compound was characterised by its inhibition of the [3H]-NMS Binding to Muscarinic acetylcholine...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(RAT)
Institute Of Research

Curated by ChEMBL
LigandPNGBDBM50403547(ATROPEN | ATROPINE)
Affinity DataKi:  1.60nMAssay Description:Inhibition of carbachol-induced release of alpha-amylase from pancreatic acinar cells from that of rat ileum contained the M2 receptor subtypesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(RAT)
Institute Of Research

Curated by ChEMBL
LigandPNGBDBM50005685(2,2-Diphenyl-propionic acid 2-diethylamino-ethyl e...)
Affinity DataKi:  1.70nMAssay Description:Inhibition of carbachol-induced release of alpha-amylase from pancreatic acinar cells from that of rat ileum contained the M2 receptor subtypesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Institute of Research

Curated by ChEMBL
LigandPNGBDBM50005681(2-Cyclohexyl-2-phenyl-propionic acid 3-dimethylami...)
Affinity DataKi:  1.70nMAssay Description:Antimuscurinic potency and subset specificity of the compound was characterised by its inhibition of the [3H]-NMS Binding to Muscarinic acetylcholine...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Institute of Research

Curated by ChEMBL
LigandPNGBDBM50005681(2-Cyclohexyl-2-phenyl-propionic acid 3-dimethylami...)
Affinity DataKi:  1.90nMAssay Description:Antimuscurinic potency and subset specificity of the compound was characterised by its inhibition of the [3H]-NMS Binding to Muscarinic acetylcholine...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(RAT)
Institute Of Research

Curated by ChEMBL
LigandPNGBDBM50018230(2-(4-Methylcarbamoyloxy-phenyl)-2-phenyl-propionic...)
Affinity DataKi:  2nMAssay Description:Binding affinity was determined from the inhibition of contraction of guinea pig ileum which has Muscarinic acetylcholine receptor M2 subtype.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Institute of Research

Curated by ChEMBL
LigandPNGBDBM50005685(2,2-Diphenyl-propionic acid 2-diethylamino-ethyl e...)
Affinity DataKi:  2.10nMAssay Description:Antimuscurinic potency and subset specificity of the compound was characterised by inhibition of the [3H]-NMS Binding to Muscarinic acetylcholine rec...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic receptor M1(Bos taurus)
Institute Of Research

Curated by ChEMBL
LigandPNGBDBM50403547(ATROPEN | ATROPINE)
Affinity DataKi:  2.40nMAssay Description:Inhibition of [3H]NMS binding to cerebral cortex membranes which contain predominantly the Muscarinic acetylcholine receptor M1 subtypesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Institute of Research

Curated by ChEMBL
LigandPNGBDBM50005684(2-Cyclohexyl-2-phenyl-propionic acid 3-diethylamin...)
Affinity DataKi:  2.90nMAssay Description:Antimuscurinic potency and subset specificity of the compound was characterised by its inhibition of the [3H]-NMS Binding to Muscarinic acetylcholine...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Institute of Research

Curated by ChEMBL
LigandPNGBDBM50005684(2-Cyclohexyl-2-phenyl-propionic acid 3-diethylamin...)
Affinity DataKi:  4nMAssay Description:Antimuscurinic potency and subset specificity of the compound was characterised by its inhibition of the [3H]-NMS Binding to Muscarinic acetylcholine...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Institute of Research

Curated by ChEMBL
LigandPNGBDBM50005686(2-Cyclohexyl-2-phenyl-propionic acid 2-diethylamin...)
Affinity DataKi:  4nMAssay Description:Antimuscurinic potency and subset specificity of the compound was characterised by its inhibition of the [3H]-NMS Binding to Muscarinic acetylcholine...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
Institute of Research

Curated by ChEMBL
LigandPNGBDBM50005684(2-Cyclohexyl-2-phenyl-propionic acid 3-diethylamin...)
Affinity DataKi:  4.60nMAssay Description:Antimuscurinic potency and subset specificity of the compound was characterised by its inhibition of the [3H]-NMS Binding to Muscarinic acetylcholine...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(RAT)
Institute Of Research

Curated by ChEMBL
LigandPNGBDBM50018229(2-(4-Hydroxy-phenyl)-2-phenyl-propionic acid 2-die...)
Affinity DataKi:  5.60nMAssay Description:Inhibition of carbachol-induced release of alpha-amylase from pancreatic acinar cells from that of rat ileum contained the M2 receptor subtypesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
Institute of Research

Curated by ChEMBL
LigandPNGBDBM50005685(2,2-Diphenyl-propionic acid 2-diethylamino-ethyl e...)
Affinity DataKi:  7.40nMAssay Description:Antimuscurinic potency and subset specificity of the compound was characterised by its inhibition of the [3H]-NMS Binding to Muscarinic acetylcholine...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Institute of Research

Curated by ChEMBL
LigandPNGBDBM50005685(2,2-Diphenyl-propionic acid 2-diethylamino-ethyl e...)
Affinity DataKi:  7.70nMAssay Description:Antimuscurinic potency and subset specificity of the compound was characterised by inhibition of the [3H]-NMS Binding to Muscarinic acetylcholine rec...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Institute of Research

Curated by ChEMBL
LigandPNGBDBM50005685(2,2-Diphenyl-propionic acid 2-diethylamino-ethyl e...)
Affinity DataKi:  9.30nMAssay Description:Antimuscurinic potency and subset specificity of the compound was characterised by inhibition of the [3H]-NMS Binding to Muscarinic acetylcholine rec...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Institute of Research

Curated by ChEMBL
LigandPNGBDBM50005686(2-Cyclohexyl-2-phenyl-propionic acid 2-diethylamin...)
Affinity DataKi:  9.90nMAssay Description:Antimuscurinic potency and subset specificity of the compound was characterised by its inhibition of the [3H]-NMS Muscarinic acetylcholine receptor M...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
Institute of Research

Curated by ChEMBL
LigandPNGBDBM50005686(2-Cyclohexyl-2-phenyl-propionic acid 2-diethylamin...)
Affinity DataKi:  19nMAssay Description:Antimuscurinic potency and subset specificity of the compound was characterised by its inhibition of the [3H]-NMS Binding to Muscarinic acetylcholine...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Institute of Research

Curated by ChEMBL
LigandPNGBDBM50005684(2-Cyclohexyl-2-phenyl-propionic acid 3-diethylamin...)
Affinity DataKi:  20nMAssay Description:Antimuscurinic potency and subset specificity of the compound was characterised by its inhibition of the [3H]-NMS Binding to Muscarinic acetylcholine...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50005685(2,2-Diphenyl-propionic acid 2-diethylamino-ethyl e...)
Affinity DataKi:  23nMAssay Description:Inhibit the binding of [N-mnethyl-3H]-scopolamine [3H]-NMS) to Muscarinic acetylcholine receptor of human IRM-30 neuroblastoma cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Institute of Research

Curated by ChEMBL
LigandPNGBDBM50005686(2-Cyclohexyl-2-phenyl-propionic acid 2-diethylamin...)
Affinity DataKi:  23nMAssay Description:Antimuscurinic potency and subset specificity of the compound was characterised by its inhibition of the [3H]-NMS Binding to Muscarinic acetylcholine...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic receptor M1(Bos taurus)
Institute Of Research

Curated by ChEMBL
LigandPNGBDBM50018230(2-(4-Methylcarbamoyloxy-phenyl)-2-phenyl-propionic...)
Affinity DataKi:  26nMAssay Description:Inhibition of [3H]NMS binding to cerebral cortex membranes which contain predominantly the Muscarinic acetylcholine receptor M1 subtypesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Institute of Research

Curated by ChEMBL
LigandPNGBDBM50005681(2-Cyclohexyl-2-phenyl-propionic acid 3-dimethylami...)
Affinity DataKi:  27nMAssay Description:Antimuscurinic potency and subset specificity of the compound was characterised by its inhibition of the [3H]-NMS Binding to Muscarinic acetylcholine...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Institute of Research

Curated by ChEMBL
LigandPNGBDBM50005682(2-Cyclohexyl-2-phenyl-propionic acid 4-dimethylami...)
Affinity DataKi:  31nMAssay Description:Antimuscurinic potency and subset specificity of the compound was characterised by its inhibition of the [3H]-NMS Binding to Muscarinic acetylcholine...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Institute of Research

Curated by ChEMBL
LigandPNGBDBM50005682(2-Cyclohexyl-2-phenyl-propionic acid 4-dimethylami...)
Affinity DataKi:  41nMAssay Description:Antimuscurinic potency and subset specificity of the compound was characterised by its inhibition of the [3H]-NMS Binding to Muscarinic acetylcholine...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(RAT)
Institute Of Research

Curated by ChEMBL
LigandPNGBDBM50018225(2-(4-Dimethylcarbamoyloxy-phenyl)-2-phenyl-propion...)
Affinity DataKi:  42nMAssay Description:Binding affinity was determined from the inhibition of contraction of guinea pig ileum which has Muscarinic acetylcholine receptor M2 subtype.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic receptor M1(Bos taurus)
Institute Of Research

Curated by ChEMBL
LigandPNGBDBM50005685(2,2-Diphenyl-propionic acid 2-diethylamino-ethyl e...)
Affinity DataKi:  51nMAssay Description:Inhibition of [3H]NMS binding to cerebral cortex membranes which contain predominantly the Muscarinic acetylcholine receptor M1 subtypesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
Institute of Research

Curated by ChEMBL
LigandPNGBDBM50005682(2-Cyclohexyl-2-phenyl-propionic acid 4-dimethylami...)
Affinity DataKi:  66nMAssay Description:Antimuscurinic potency and subset specificity of the compound was characterised by its inhibition of the [3H]-NMS Binding to Muscarinic acetylcholine...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic receptor M1(Bos taurus)
Institute Of Research

Curated by ChEMBL
LigandPNGBDBM50018229(2-(4-Hydroxy-phenyl)-2-phenyl-propionic acid 2-die...)
Affinity DataKi:  100nMAssay Description:Inhibition of [3H]NMS binding to cerebral cortex membranes which contain predominantly the Muscarinic acetylcholine receptor M1 subtypesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Institute of Research

Curated by ChEMBL
LigandPNGBDBM50005683(2-Cyclohexyl-2-phenyl-propionic acid 4-diethylamin...)
Affinity DataKi:  111nMAssay Description:Antimuscurinic potency and subset specificity of the compound was characterised by its inhibition of the [3H]-NMS Binding to Muscarinic acetylcholine...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(RAT)
Institute Of Research

Curated by ChEMBL
LigandPNGBDBM39341(11-[(4-methylpiperazin-1-yl)acetyl]-5,11-dihydro-6...)
Affinity DataKi:  120nMAssay Description:Inhibition of carbachol-induced release of alpha-amylase from pancreatic acinar cells from that of rat ileum contained the muscarinic acetylcholine r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic receptor M1(Bos taurus)
Institute Of Research

Curated by ChEMBL
LigandPNGBDBM50018225(2-(4-Dimethylcarbamoyloxy-phenyl)-2-phenyl-propion...)
Affinity DataKi:  150nMAssay Description:Inhibition of [3H]NMS binding to cerebral cortex membranes which contain predominantly the Muscarinic acetylcholine receptor M1 subtypesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Institute of Research

Curated by ChEMBL
LigandPNGBDBM50005683(2-Cyclohexyl-2-phenyl-propionic acid 4-diethylamin...)
Affinity DataKi:  160nMAssay Description:Antimuscurinic potency and subset specificity of the compound was characterised by its inhibition of the [3H]-NMS Binding to Muscarinic acetylcholine...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic receptor M1(Bos taurus)
Institute Of Research

Curated by ChEMBL
LigandPNGBDBM39341(11-[(4-methylpiperazin-1-yl)acetyl]-5,11-dihydro-6...)
Affinity DataKi:  170nMAssay Description:Inhibition of [3H]NMS binding to cerebral cortex membranes which contain predominantly the muscarinic acetylcholine receptor M1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
Institute of Research

Curated by ChEMBL
LigandPNGBDBM50005680(2-Cyclohexyl-2-phenyl-propionic acid 5-diethylamin...)
Affinity DataKi:  173nMAssay Description:Antimuscurinic potency and subset specificity of the compound was characterised by its inhibition of the [3H]-NMS Binding to Muscarinic acetylcholine...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Institute of Research

Curated by ChEMBL
LigandPNGBDBM50005680(2-Cyclohexyl-2-phenyl-propionic acid 5-diethylamin...)
Affinity DataKi:  178nMAssay Description:Antimuscurinic potency and subset specificity of the compound was characterised by its inhibition of the [3H]-NMS Binding to Muscarinic acetylcholine...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
Institute of Research

Curated by ChEMBL
LigandPNGBDBM50005683(2-Cyclohexyl-2-phenyl-propionic acid 4-diethylamin...)
Affinity DataKi:  209nMAssay Description:Antimuscurinic potency and subset specificity of the compound was characterised by its inhibition of the [3H]-NMS Binding to Muscarinic acetylcholine...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Institute of Research

Curated by ChEMBL
LigandPNGBDBM50005680(2-Cyclohexyl-2-phenyl-propionic acid 5-diethylamin...)
Affinity DataKi:  246nMAssay Description:Antimuscurinic potency and subset specificity of the compound was characterised by its inhibition of the [3H]-NMS Binding to Muscarinic acetylcholine...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Institute of Research

Curated by ChEMBL
LigandPNGBDBM50005683(2-Cyclohexyl-2-phenyl-propionic acid 4-diethylamin...)
Affinity DataKi:  248nMAssay Description:Antimuscurinic potency and subset specificity of the compound was characterised by its inhibition of the [3H]-NMS Binding to Muscarinic acetylcholine...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Institute of Research

Curated by ChEMBL
LigandPNGBDBM50005682(2-Cyclohexyl-2-phenyl-propionic acid 4-dimethylami...)
Affinity DataKi:  258nMAssay Description:Antimuscurinic potency and subset specificity of the compound was characterised by its inhibition of the [3H]-NMS Binding to Muscarinic acetylcholine...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Institute of Research

Curated by ChEMBL
LigandPNGBDBM50005680(2-Cyclohexyl-2-phenyl-propionic acid 5-diethylamin...)
Affinity DataKi:  298nMAssay Description:Antimuscurinic potency and subset specificity of the compound was characterised by its inhibition of the [3H]-NMS Binding to Muscarinic acetylcholine...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Institute Of Research

Curated by ChEMBL
LigandPNGBDBM50018226(2-(4-Dimethylcarbamoyloxy-phenyl)-2-(4-hydroxy-phe...)
Affinity DataKi:  800nMAssay Description:Inhibition of anticholinesterase activity by their ability to inactivate human serum butyrylcholinesteraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Institute Of Research

Curated by ChEMBL
LigandPNGBDBM50018225(2-(4-Dimethylcarbamoyloxy-phenyl)-2-phenyl-propion...)
Affinity DataKi:  1.30E+3nMAssay Description:Inhibition of anticholinesterase activity by their ability to inactivate human serum butyrylcholinesteraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Institute Of Research

Curated by ChEMBL
LigandPNGBDBM50018230(2-(4-Methylcarbamoyloxy-phenyl)-2-phenyl-propionic...)
Affinity DataKi:  1.40E+3nMAssay Description:Anticholinesterase activity by their ability to inactivate human serum butyrylcholinesteraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic receptor M1(Bos taurus)
Institute Of Research

Curated by ChEMBL
LigandPNGBDBM50018227(2,2-Bis-(4-hydroxy-phenyl)-propionic acid 2-diethy...)
Affinity DataKi:  2.10E+3nMAssay Description:Inhibition of [3H]NMS binding to cerebral cortex membranes which contain predominantly the Muscarinic acetylcholine receptor M1 subtypesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(RAT)
Institute Of Research

Curated by ChEMBL
LigandPNGBDBM50018226(2-(4-Dimethylcarbamoyloxy-phenyl)-2-(4-hydroxy-phe...)
Affinity DataKi:  2.40E+3nMAssay Description:Inhibition of carbachol-induced release of alpha-amylase from pancreatic acinar cells from that of rat ileum contained the M2 receptor subtypesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Equus caballus (Horse))
Institute Of Research

Curated by ChEMBL
LigandPNGBDBM50109574(3-Dimethylcarbamoyloxy-2-(2,2-diphenyl-propionylox...)
Affinity DataKi:  3.14E+3nMAssay Description:Inhibitory activity against Butyrylcholinesterase (BChE)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic receptor M1(Bos taurus)
Institute Of Research

Curated by ChEMBL
LigandPNGBDBM50018226(2-(4-Dimethylcarbamoyloxy-phenyl)-2-(4-hydroxy-phe...)
Affinity DataKi:  3.40E+3nMAssay Description:Inhibition of [3H]NMS binding to cerebral cortex membranes which contain predominantly the Muscarinic acetylcholine receptor M1 subtypesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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