Affinity DataKi: 0.270nMAssay Description:Inhibit the binding of [N-mnethyl-3H]-scopolamine [3H]-NMS) to Muscarinic acetylcholine receptor of human IRM-30 neuroblastoma cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Inhibit the binding of [N-mnethyl-3H]-scopolamine [3H]-NMS) to Muscarinic acetylcholine receptor of human IRM-30 neuroblastoma cellsMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
Institute of Research
Curated by ChEMBL
Institute of Research
Curated by ChEMBL
Affinity DataKi: 1.5nMAssay Description:Antimuscurinic potency and subset specificity of the compound was characterised by its inhibition of the [3H]-NMS Binding to Muscarinic acetylcholine...More data for this Ligand-Target Pair
Affinity DataKi: 1.60nMAssay Description:Inhibition of carbachol-induced release of alpha-amylase from pancreatic acinar cells from that of rat ileum contained the M2 receptor subtypesMore data for this Ligand-Target Pair
Affinity DataKi: 1.70nMAssay Description:Inhibition of carbachol-induced release of alpha-amylase from pancreatic acinar cells from that of rat ileum contained the M2 receptor subtypesMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Institute of Research
Curated by ChEMBL
Institute of Research
Curated by ChEMBL
Affinity DataKi: 1.70nMAssay Description:Antimuscurinic potency and subset specificity of the compound was characterised by its inhibition of the [3H]-NMS Binding to Muscarinic acetylcholine...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Institute of Research
Curated by ChEMBL
Institute of Research
Curated by ChEMBL
Affinity DataKi: 1.90nMAssay Description:Antimuscurinic potency and subset specificity of the compound was characterised by its inhibition of the [3H]-NMS Binding to Muscarinic acetylcholine...More data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Binding affinity was determined from the inhibition of contraction of guinea pig ileum which has Muscarinic acetylcholine receptor M2 subtype.More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Institute of Research
Curated by ChEMBL
Institute of Research
Curated by ChEMBL
Affinity DataKi: 2.10nMAssay Description:Antimuscurinic potency and subset specificity of the compound was characterised by inhibition of the [3H]-NMS Binding to Muscarinic acetylcholine rec...More data for this Ligand-Target Pair
Affinity DataKi: 2.40nMAssay Description:Inhibition of [3H]NMS binding to cerebral cortex membranes which contain predominantly the Muscarinic acetylcholine receptor M1 subtypesMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Institute of Research
Curated by ChEMBL
Institute of Research
Curated by ChEMBL
Affinity DataKi: 2.90nMAssay Description:Antimuscurinic potency and subset specificity of the compound was characterised by its inhibition of the [3H]-NMS Binding to Muscarinic acetylcholine...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Institute of Research
Curated by ChEMBL
Institute of Research
Curated by ChEMBL
Affinity DataKi: 4nMAssay Description:Antimuscurinic potency and subset specificity of the compound was characterised by its inhibition of the [3H]-NMS Binding to Muscarinic acetylcholine...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Institute of Research
Curated by ChEMBL
Institute of Research
Curated by ChEMBL
Affinity DataKi: 4nMAssay Description:Antimuscurinic potency and subset specificity of the compound was characterised by its inhibition of the [3H]-NMS Binding to Muscarinic acetylcholine...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
Institute of Research
Curated by ChEMBL
Institute of Research
Curated by ChEMBL
Affinity DataKi: 4.60nMAssay Description:Antimuscurinic potency and subset specificity of the compound was characterised by its inhibition of the [3H]-NMS Binding to Muscarinic acetylcholine...More data for this Ligand-Target Pair
Affinity DataKi: 5.60nMAssay Description:Inhibition of carbachol-induced release of alpha-amylase from pancreatic acinar cells from that of rat ileum contained the M2 receptor subtypesMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
Institute of Research
Curated by ChEMBL
Institute of Research
Curated by ChEMBL
Affinity DataKi: 7.40nMAssay Description:Antimuscurinic potency and subset specificity of the compound was characterised by its inhibition of the [3H]-NMS Binding to Muscarinic acetylcholine...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Institute of Research
Curated by ChEMBL
Institute of Research
Curated by ChEMBL
Affinity DataKi: 7.70nMAssay Description:Antimuscurinic potency and subset specificity of the compound was characterised by inhibition of the [3H]-NMS Binding to Muscarinic acetylcholine rec...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Institute of Research
Curated by ChEMBL
Institute of Research
Curated by ChEMBL
Affinity DataKi: 9.30nMAssay Description:Antimuscurinic potency and subset specificity of the compound was characterised by inhibition of the [3H]-NMS Binding to Muscarinic acetylcholine rec...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Institute of Research
Curated by ChEMBL
Institute of Research
Curated by ChEMBL
Affinity DataKi: 9.90nMAssay Description:Antimuscurinic potency and subset specificity of the compound was characterised by its inhibition of the [3H]-NMS Muscarinic acetylcholine receptor M...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
Institute of Research
Curated by ChEMBL
Institute of Research
Curated by ChEMBL
Affinity DataKi: 19nMAssay Description:Antimuscurinic potency and subset specificity of the compound was characterised by its inhibition of the [3H]-NMS Binding to Muscarinic acetylcholine...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Institute of Research
Curated by ChEMBL
Institute of Research
Curated by ChEMBL
Affinity DataKi: 20nMAssay Description:Antimuscurinic potency and subset specificity of the compound was characterised by its inhibition of the [3H]-NMS Binding to Muscarinic acetylcholine...More data for this Ligand-Target Pair
Affinity DataKi: 23nMAssay Description:Inhibit the binding of [N-mnethyl-3H]-scopolamine [3H]-NMS) to Muscarinic acetylcholine receptor of human IRM-30 neuroblastoma cellsMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Institute of Research
Curated by ChEMBL
Institute of Research
Curated by ChEMBL
Affinity DataKi: 23nMAssay Description:Antimuscurinic potency and subset specificity of the compound was characterised by its inhibition of the [3H]-NMS Binding to Muscarinic acetylcholine...More data for this Ligand-Target Pair
Affinity DataKi: 26nMAssay Description:Inhibition of [3H]NMS binding to cerebral cortex membranes which contain predominantly the Muscarinic acetylcholine receptor M1 subtypesMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Institute of Research
Curated by ChEMBL
Institute of Research
Curated by ChEMBL
Affinity DataKi: 27nMAssay Description:Antimuscurinic potency and subset specificity of the compound was characterised by its inhibition of the [3H]-NMS Binding to Muscarinic acetylcholine...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Institute of Research
Curated by ChEMBL
Institute of Research
Curated by ChEMBL
Affinity DataKi: 31nMAssay Description:Antimuscurinic potency and subset specificity of the compound was characterised by its inhibition of the [3H]-NMS Binding to Muscarinic acetylcholine...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Institute of Research
Curated by ChEMBL
Institute of Research
Curated by ChEMBL
Affinity DataKi: 41nMAssay Description:Antimuscurinic potency and subset specificity of the compound was characterised by its inhibition of the [3H]-NMS Binding to Muscarinic acetylcholine...More data for this Ligand-Target Pair
Affinity DataKi: 42nMAssay Description:Binding affinity was determined from the inhibition of contraction of guinea pig ileum which has Muscarinic acetylcholine receptor M2 subtype.More data for this Ligand-Target Pair
Affinity DataKi: 51nMAssay Description:Inhibition of [3H]NMS binding to cerebral cortex membranes which contain predominantly the Muscarinic acetylcholine receptor M1 subtypesMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
Institute of Research
Curated by ChEMBL
Institute of Research
Curated by ChEMBL
Affinity DataKi: 66nMAssay Description:Antimuscurinic potency and subset specificity of the compound was characterised by its inhibition of the [3H]-NMS Binding to Muscarinic acetylcholine...More data for this Ligand-Target Pair
Affinity DataKi: 100nMAssay Description:Inhibition of [3H]NMS binding to cerebral cortex membranes which contain predominantly the Muscarinic acetylcholine receptor M1 subtypesMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Institute of Research
Curated by ChEMBL
Institute of Research
Curated by ChEMBL
Affinity DataKi: 111nMAssay Description:Antimuscurinic potency and subset specificity of the compound was characterised by its inhibition of the [3H]-NMS Binding to Muscarinic acetylcholine...More data for this Ligand-Target Pair
Affinity DataKi: 120nMAssay Description:Inhibition of carbachol-induced release of alpha-amylase from pancreatic acinar cells from that of rat ileum contained the muscarinic acetylcholine r...More data for this Ligand-Target Pair
Affinity DataKi: 150nMAssay Description:Inhibition of [3H]NMS binding to cerebral cortex membranes which contain predominantly the Muscarinic acetylcholine receptor M1 subtypesMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Institute of Research
Curated by ChEMBL
Institute of Research
Curated by ChEMBL
Affinity DataKi: 160nMAssay Description:Antimuscurinic potency and subset specificity of the compound was characterised by its inhibition of the [3H]-NMS Binding to Muscarinic acetylcholine...More data for this Ligand-Target Pair
Affinity DataKi: 170nMAssay Description:Inhibition of [3H]NMS binding to cerebral cortex membranes which contain predominantly the muscarinic acetylcholine receptor M1More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
Institute of Research
Curated by ChEMBL
Institute of Research
Curated by ChEMBL
Affinity DataKi: 173nMAssay Description:Antimuscurinic potency and subset specificity of the compound was characterised by its inhibition of the [3H]-NMS Binding to Muscarinic acetylcholine...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Institute of Research
Curated by ChEMBL
Institute of Research
Curated by ChEMBL
Affinity DataKi: 178nMAssay Description:Antimuscurinic potency and subset specificity of the compound was characterised by its inhibition of the [3H]-NMS Binding to Muscarinic acetylcholine...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
Institute of Research
Curated by ChEMBL
Institute of Research
Curated by ChEMBL
Affinity DataKi: 209nMAssay Description:Antimuscurinic potency and subset specificity of the compound was characterised by its inhibition of the [3H]-NMS Binding to Muscarinic acetylcholine...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Institute of Research
Curated by ChEMBL
Institute of Research
Curated by ChEMBL
Affinity DataKi: 246nMAssay Description:Antimuscurinic potency and subset specificity of the compound was characterised by its inhibition of the [3H]-NMS Binding to Muscarinic acetylcholine...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Institute of Research
Curated by ChEMBL
Institute of Research
Curated by ChEMBL
Affinity DataKi: 248nMAssay Description:Antimuscurinic potency and subset specificity of the compound was characterised by its inhibition of the [3H]-NMS Binding to Muscarinic acetylcholine...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Institute of Research
Curated by ChEMBL
Institute of Research
Curated by ChEMBL
Affinity DataKi: 258nMAssay Description:Antimuscurinic potency and subset specificity of the compound was characterised by its inhibition of the [3H]-NMS Binding to Muscarinic acetylcholine...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Institute of Research
Curated by ChEMBL
Institute of Research
Curated by ChEMBL
Affinity DataKi: 298nMAssay Description:Antimuscurinic potency and subset specificity of the compound was characterised by its inhibition of the [3H]-NMS Binding to Muscarinic acetylcholine...More data for this Ligand-Target Pair
Affinity DataKi: 800nMAssay Description:Inhibition of anticholinesterase activity by their ability to inactivate human serum butyrylcholinesteraseMore data for this Ligand-Target Pair
Affinity DataKi: 1.30E+3nMAssay Description:Inhibition of anticholinesterase activity by their ability to inactivate human serum butyrylcholinesteraseMore data for this Ligand-Target Pair
Affinity DataKi: 1.40E+3nMAssay Description:Anticholinesterase activity by their ability to inactivate human serum butyrylcholinesteraseMore data for this Ligand-Target Pair
Affinity DataKi: 2.10E+3nMAssay Description:Inhibition of [3H]NMS binding to cerebral cortex membranes which contain predominantly the Muscarinic acetylcholine receptor M1 subtypesMore data for this Ligand-Target Pair
Affinity DataKi: 2.40E+3nMAssay Description:Inhibition of carbachol-induced release of alpha-amylase from pancreatic acinar cells from that of rat ileum contained the M2 receptor subtypesMore data for this Ligand-Target Pair
Affinity DataKi: 3.14E+3nMAssay Description:Inhibitory activity against Butyrylcholinesterase (BChE)More data for this Ligand-Target Pair
Affinity DataKi: 3.40E+3nMAssay Description:Inhibition of [3H]NMS binding to cerebral cortex membranes which contain predominantly the Muscarinic acetylcholine receptor M1 subtypesMore data for this Ligand-Target Pair