Affinity DataKi: 39nMAssay Description:Inhibition of recombinant human MIF tautomerase activity expressed in Escherichia coli assessed as decrease in formation of borate complex of enol pr...More data for this Ligand-Target Pair
Affinity DataKi: 40nMAssay Description:Inhibition of human SphK1 expressed in baculovirus infected in Sf9 cells using D-erythro-sphingosine as substrate and [gamma-32P]ATP by scintillation...More data for this Ligand-Target Pair
Affinity DataKi: 48nMAssay Description:Inhibition of recombinant human MIF tautomerase activity expressed in Escherichia coli assessed as decrease in formation of borate complex of enol pr...More data for this Ligand-Target Pair
Affinity DataKi: 70nMAssay Description:Inhibition of human SphK1 expressed in baculovirus infected in Sf9 cells using D-erythro-sphingosine as substrate and [gamma-32P]ATP by scintillation...More data for this Ligand-Target Pair
Affinity DataKi: 74nMAssay Description:Inhibition of recombinant human MIF tautomerase activity expressed in Escherichia coli assessed as decrease in formation of borate complex of enol pr...More data for this Ligand-Target Pair
Affinity DataKi: 75nMAssay Description:Inhibition of recombinant human MIF tautomerase activity expressed in Escherichia coli assessed as decrease in formation of borate complex of enol pr...More data for this Ligand-Target Pair
Affinity DataKi: 90nMAssay Description:Inhibition of recombinant human MIF tautomerase activity expressed in Escherichia coli assessed as decrease in formation of borate complex of enol pr...More data for this Ligand-Target Pair
Affinity DataKi: 100nMAssay Description:Inhibition of human SphK1 expressed in baculovirus infected in Sf9 cells using D-erythro-sphingosine as substrate and [gamma-32P]ATP by scintillation...More data for this Ligand-Target Pair
Affinity DataKi: 144nMAssay Description:Inhibition of recombinant human MIF tautomerase activity expressed in Escherichia coli assessed as decrease in formation of borate complex of enol pr...More data for this Ligand-Target Pair
Affinity DataKi: 160nMAssay Description:Inhibition of recombinant human MIF tautomerase activity expressed in Escherichia coli assessed as decrease in formation of borate complex of enol pr...More data for this Ligand-Target Pair
Affinity DataKi: 200nMAssay Description:Inhibition of human SphK1 expressed in baculovirus infected in Sf9 cells using D-erythro-sphingosine as substrate and [gamma-32P]ATP by scintillation...More data for this Ligand-Target Pair
Affinity DataKi: 200nMAssay Description:Inhibition of recombinant human MIF tautomerase activity expressed in Escherichia coli assessed as decrease in formation of borate complex of enol pr...More data for this Ligand-Target Pair
Affinity DataKi: 230nMAssay Description:Inhibition of recombinant human MIF tautomerase activity expressed in Escherichia coli assessed as decrease in formation of borate complex of enol pr...More data for this Ligand-Target Pair
Affinity DataKi: 260nMAssay Description:Inhibition of recombinant human MIF tautomerase activity expressed in Escherichia coli assessed as decrease in formation of borate complex of enol pr...More data for this Ligand-Target Pair
Affinity DataKi: 260nMAssay Description:Inhibition of human SphK1 expressed in baculovirus infected in Sf9 cells using D-erythro-sphingosine as substrate and [gamma-32P]ATP by scintillation...More data for this Ligand-Target Pair
Affinity DataKi: 320nMAssay Description:Inhibition of human SphK1 expressed in baculovirus infected in Sf9 cells using D-erythro-sphingosine as substrate and [gamma-32P]ATP by scintillation...More data for this Ligand-Target Pair
Affinity DataKi: 360nMAssay Description:Inhibition of recombinant human MIF tautomerase activity expressed in Escherichia coli assessed as decrease in formation of borate complex of enol pr...More data for this Ligand-Target Pair
Affinity DataKi: 363nMAssay Description:Inhibition of recombinant human MIF tautomerase activity expressed in Escherichia coli assessed as decrease in formation of borate complex of enol pr...More data for this Ligand-Target Pair
Affinity DataKi: 400nMAssay Description:Inhibition of human SphK1 expressed in baculovirus infected in Sf9 cells using D-erythro-sphingosine as substrate and [gamma-32P]ATP by scintillation...More data for this Ligand-Target Pair
Affinity DataKi: 440nMAssay Description:Inhibition of human SphK1 expressed in baculovirus infected in Sf9 cells using D-erythro-sphingosine as substrate and [gamma-32P]ATP by scintillation...More data for this Ligand-Target Pair
Affinity DataKi: 530nMAssay Description:Inhibition of recombinant human MIF tautomerase activity expressed in Escherichia coli assessed as decrease in formation of borate complex of enol pr...More data for this Ligand-Target Pair
Affinity DataKi: 980nMAssay Description:Inhibition of human SphK1 expressed in baculovirus infected in Sf9 cells using D-erythro-sphingosine as substrate and [gamma-32P]ATP by scintillation...More data for this Ligand-Target Pair
Affinity DataKi: 1.20E+3nMAssay Description:Inhibition of human SphK2 expressed in baculovirus infected in Sf9 cells using D-erythro-sphingosine as substrate and [gamma-32P]ATP by scintillation...More data for this Ligand-Target Pair
Affinity DataKi: 1.60E+3nMAssay Description:Inhibition of human SphK1 expressed in baculovirus infected in Sf9 cells using D-erythro-sphingosine as substrate and [gamma-32P]ATP by scintillation...More data for this Ligand-Target Pair
Affinity DataKi: 2.50E+3nMAssay Description:Inhibition of human SphK1 expressed in baculovirus infected in Sf9 cells using D-erythro-sphingosine as substrate and [gamma-32P]ATP by scintillation...More data for this Ligand-Target Pair
Affinity DataKi: 3.00E+3nMAssay Description:Inhibition of human SphK1 expressed in baculovirus infected in Sf9 cells using D-erythro-sphingosine as substrate and [gamma-32P]ATP by scintillation...More data for this Ligand-Target Pair
Affinity DataKi: 3.40E+3nMAssay Description:Inhibition of human SphK2 expressed in baculovirus infected in Sf9 cells using D-erythro-sphingosine as substrate and [gamma-32P]ATP by scintillation...More data for this Ligand-Target Pair
Affinity DataKi: 4.60E+3nMAssay Description:Inhibition of human SphK1 expressed in baculovirus infected in Sf9 cells using D-erythro-sphingosine as substrate and [gamma-32P]ATP by scintillation...More data for this Ligand-Target Pair
Affinity DataKi: 6.00E+3nMAssay Description:Inhibition of human SphK2 expressed in baculovirus infected in Sf9 cells using D-erythro-sphingosine as substrate and [gamma-32P]ATP by scintillation...More data for this Ligand-Target Pair
Affinity DataKi: 6.00E+3nMAssay Description:Inhibition of human SphK2 expressed in baculovirus infected in Sf9 cells using D-erythro-sphingosine as substrate and [gamma-32P]ATP by scintillation...More data for this Ligand-Target Pair
Affinity DataKi: 8.10E+3nMAssay Description:Inhibition of human SphK2 expressed in baculovirus infected in Sf9 cells using D-erythro-sphingosine as substrate and [gamma-32P]ATP by scintillation...More data for this Ligand-Target Pair
Affinity DataKi: 9.90E+3nMAssay Description:Inhibition of human SphK2 expressed in baculovirus infected in Sf9 cells using D-erythro-sphingosine as substrate and [gamma-32P]ATP by scintillation...More data for this Ligand-Target Pair
Affinity DataKi: 1.02E+4nMAssay Description:Inhibition of human SphK2 expressed in baculovirus infected in Sf9 cells using D-erythro-sphingosine as substrate and [gamma-32P]ATP by scintillation...More data for this Ligand-Target Pair
Affinity DataKi: 1.03E+4nMAssay Description:Inhibition of human SphK2 expressed in baculovirus infected in Sf9 cells using D-erythro-sphingosine as substrate and [gamma-32P]ATP by scintillation...More data for this Ligand-Target Pair
Affinity DataKi: 1.09E+4nMAssay Description:Inhibition of human SphK2 expressed in baculovirus infected in Sf9 cells using D-erythro-sphingosine as substrate and [gamma-32P]ATP by scintillation...More data for this Ligand-Target Pair
Affinity DataKi: 1.10E+4nMAssay Description:Inhibition of human SphK2 expressed in baculovirus infected in Sf9 cells using D-erythro-sphingosine as substrate and [gamma-32P]ATP by scintillation...More data for this Ligand-Target Pair
Affinity DataKi: 1.17E+4nMAssay Description:Inhibition of human SphK2 expressed in baculovirus infected in Sf9 cells using D-erythro-sphingosine as substrate and [gamma-32P]ATP by scintillation...More data for this Ligand-Target Pair
Affinity DataKi: 1.41E+4nMAssay Description:Inhibition of human SphK2 expressed in baculovirus infected in Sf9 cells using D-erythro-sphingosine as substrate and [gamma-32P]ATP by scintillation...More data for this Ligand-Target Pair
Affinity DataKi: 3.01E+4nMAssay Description:Inhibition of recombinant human MIF tautomerase activity expressed in Escherichia coli assessed as decrease in formation of borate complex of enol pr...More data for this Ligand-Target Pair
Affinity DataKi: 4.30E+4nMAssay Description:Inhibition of human SphK2 expressed in baculovirus infected in Sf9 cells using D-erythro-sphingosine as substrate and [gamma-32P]ATP by scintillation...More data for this Ligand-Target Pair
Affinity DataIC50: 2.96E+3nMAssay Description:Inhibition of wild type full length human JAK2 (1 to 1132 residues) autophosphorylation expressed in HEK293T cells incubated in buffer with compound ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.11E+4nMAssay Description:Inhibition of full length human C-terminal FLAG-tagged JAK2 V617F mutant (1 to 1132 residues) autophosphorylation expressed in HEK293T cells incubate...More data for this Ligand-Target Pair
Affinity DataIC50: 4.65E+4nMAssay Description:Inhibition of wild type full length human JAK2 (1 to 1132 residues) autophosphorylation expressed in HEK293T cells incubated in buffer with compound ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of full length human C-terminal FLAG-tagged JAK2 V617F mutant (1 to 1132 residues) autophosphorylation expressed in HEK293T cells incubate...More data for this Ligand-Target Pair
Affinity DataKd: 160nMAssay Description:Inhibition of recombinant human MIF tautomerase activity assessed as decrease in formation of borate complex of enol product using 4-HPP as substrate...More data for this Ligand-Target Pair
Affinity DataKd: 350nMAssay Description:Inhibition of recombinant human MIF tautomerase activity assessed as decrease in formation of borate complex of enol product using 4-HPP as substrate...More data for this Ligand-Target Pair
Affinity DataKd: 150nMAssay Description:Inhibition of recombinant human MIF tautomerase activity assessed as decrease in formation of borate complex of enol product using 4-HPP as substrate...More data for this Ligand-Target Pair
Affinity DataKd: 260nMAssay Description:Inhibition of recombinant human MIF tautomerase activity assessed as decrease in formation of borate complex of enol product using 4-HPP as substrate...More data for this Ligand-Target Pair
Affinity DataKd: 63nMAssay Description:Inhibition of recombinant human MIF tautomerase activity assessed as decrease in formation of borate complex of enol product using 4-HPP as substrate...More data for this Ligand-Target Pair
Affinity DataKd: 213nMAssay Description:Inhibition of recombinant human MIF tautomerase activity assessed as decrease in formation of borate complex of enol product using 4-HPP as substrate...More data for this Ligand-Target Pair