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Found 40 with Last Name = 'dehouck' and Initial = 'mp'
TargetMonoglyceride lipase(Rattus norvegicus (Rat))
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50160284(CHEMBL3785379)
Affinity DataIC50:  0.25nMAssay Description:Inhibition of rat MAGLMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonoglyceride lipase(Homo sapiens (Human))
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50160282(CHEMBL3785760)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of recombinant C-terminal His6-tagged human MAGL expressed in Escherichia coli using 2-arachidonoyl-[3H]-glycerol as substrate incubated f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonoglyceride lipase(Homo sapiens (Human))
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50160284(CHEMBL3785379)
Affinity DataIC50:  4.60nMAssay Description:Inhibition of recombinant C-terminal His6-tagged human MAGL expressed in Escherichia coli using 2-arachidonoyl-[3H]-glycerol as substrate incubated f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonoglyceride lipase(Homo sapiens (Human))
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50160284(CHEMBL3785379)
Affinity DataIC50:  4.60nMAssay Description:Inhibition of recombinant C-terminal His6-tagged human MAGL expressed in Escherichia coli using 2-arachidonoyl-[3H]-glycerol as substrate incubated f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonoglyceride lipase(Rattus norvegicus (Rat))
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50160284(CHEMBL3785379)
Affinity DataIC50:  10nMAssay Description:Inhibition of MAGL in rat brain membranes preincubated for 20 mins followed by fluorophosphonate-rhodamine addition measured after 30 mins by competi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonoglyceride lipase(Homo sapiens (Human))
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50160280(CHEMBL3787340)
Affinity DataIC50:  13nMAssay Description:Inhibition of recombinant C-terminal His6-tagged human MAGL expressed in Escherichia coli using 2-arachidonoyl-[3H]-glycerol as substrate incubated f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonoglyceride lipase(Homo sapiens (Human))
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50160277(CHEMBL3785536)
Affinity DataIC50:  23nMAssay Description:Inhibition of recombinant C-terminal His6-tagged human MAGL expressed in Escherichia coli using 2-arachidonoyl-[3H]-glycerol as substrate incubated f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonoglyceride lipase(Homo sapiens (Human))
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50160283(CHEMBL3787346)
Affinity DataIC50:  31nMAssay Description:Inhibition of recombinant C-terminal His6-tagged human MAGL expressed in Escherichia coli using 2-arachidonoyl-[3H]-glycerol as substrate incubated f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonoglyceride lipase(Homo sapiens (Human))
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50160279(CHEMBL3787224)
Affinity DataIC50:  61nMAssay Description:Inhibition of recombinant C-terminal His6-tagged human MAGL expressed in Escherichia coli using 2-arachidonoyl-[3H]-glycerol as substrate incubated f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonoglyceride lipase(Homo sapiens (Human))
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50160281(CHEMBL3787592)
Affinity DataIC50:  98nMAssay Description:Inhibition of human MAGL expressed in African green monkey COS cells using 2-arachidonoyl-[3H]-glycerol as substrate incubated for 20 mins by scintil...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonoglyceride lipase(Homo sapiens (Human))
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50160284(CHEMBL3785379)
Affinity DataIC50:  195nMAssay Description:Inhibition of recombinant C-terminal His6-tagged human MAGL expressed in Escherichia coli using 2-arachidonoyl-[3H]-glycerol as substrate preincubate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonoglyceride lipase(Homo sapiens (Human))
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50160284(CHEMBL3785379)
Affinity DataIC50:  196nMAssay Description:Inhibition of recombinant C-terminal His6-tagged human MAGL expressed in Escherichia coli using 2-arachidonoyl-[3H]-glycerol as substrate preincubate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonoglyceride lipase(Homo sapiens (Human))
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50160278(CHEMBL3786142)
Affinity DataIC50:  251nMAssay Description:Inhibition of recombinant C-terminal His6-tagged human MAGL expressed in Escherichia coli using 2-arachidonoyl-[3H]-glycerol as substrate incubated f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonoglyceride lipase(Homo sapiens (Human))
University Of Siena

Curated by ChEMBL
LigandPNGBDBM60622(BDBM50300355 | US11753371, Compound JZL-184 | US91...)
Affinity DataIC50:  285nMAssay Description:Inhibition of recombinant C-terminal His6-tagged human MAGL expressed in Escherichia coli using 2-arachidonoyl-[3H]-glycerol as substrate incubated f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonoglyceride lipase(Homo sapiens (Human))
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50160287(CHEMBL3787453)
Affinity DataIC50:  376nMAssay Description:Inhibition of recombinant C-terminal His6-tagged human MAGL expressed in Escherichia coli using 2-arachidonoyl-[3H]-glycerol as substrate incubated f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50160279(CHEMBL3787224)
Affinity DataIC50:  725nMAssay Description:Inhibition of FAAH in rat brain membranes using using N-arachidonoyl-[14C]-ethanolamine as substrate assessed as reduction in [14C]ethanolamine produ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonoglyceride lipase(Homo sapiens (Human))
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50160283(CHEMBL3787346)
Affinity DataIC50:  729nMAssay Description:Inhibition of recombinant C-terminal His6-tagged human MAGL expressed in Escherichia coli using 2-arachidonoyl-[3H]-glycerol as substrate preincubate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50160280(CHEMBL3787340)
Affinity DataIC50:  2.59E+3nMAssay Description:Inhibition of FAAH in rat brain membranes using using N-arachidonoyl-[14C]-ethanolamine as substrate assessed as reduction in [14C]ethanolamine produ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50160277(CHEMBL3785536)
Affinity DataIC50:  3.68E+3nMAssay Description:Inhibition of FAAH in rat brain membranes using using N-arachidonoyl-[14C]-ethanolamine as substrate assessed as reduction in [14C]ethanolamine produ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50160284(CHEMBL3785379)
Affinity DataIC50:  4.05E+3nMAssay Description:Inhibition of recombinant C-terminal His-tagged human FAAH expressed in sf21 cells using N-arachidonoyl-[14C]-ethanolamine as substrate assessed as r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50160284(CHEMBL3785379)
Affinity DataIC50:  4.05E+3nMAssay Description:Inhibition of recombinant C-terminal His-tagged human FAAH expressed in sf21 cells using N-arachidonoyl-[14C]-ethanolamine as substrate assessed as r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonoglyceride lipase(Homo sapiens (Human))
University Of Siena

Curated by ChEMBL
LigandPNGBDBM60622(BDBM50300355 | US11753371, Compound JZL-184 | US91...)
Affinity DataIC50:  4.44E+3nMAssay Description:Inhibition of recombinant C-terminal His6-tagged human MAGL expressed in Escherichia coli using 2-arachidonoyl-[3H]-glycerol as substrate preincubate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50160283(CHEMBL3787346)
Affinity DataIC50:  7.74E+3nMAssay Description:Inhibition of recombinant C-terminal His-tagged human FAAH expressed in sf21 cells using N-arachidonoyl-[14C]-ethanolamine as substrate assessed as r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50160282(CHEMBL3785760)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant C-terminal His-tagged human FAAH expressed in sf21 cells using N-arachidonoyl-[14C]-ethanolamine as substrate assessed as r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50160284(CHEMBL3785379)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]-CP-55940 from human recombinant CB1 receptor expressed in HEK293 cells after 90 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50160284(CHEMBL3785379)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]-CP-55940 from human recombinant CB2 receptor expressed in HEK293 cells after 90 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonoglyceride lipase(Homo sapiens (Human))
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50160285(CHEMBL3786786)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant C-terminal His6-tagged human MAGL expressed in Escherichia coli using 2-arachidonoyl-[3H]-glycerol as substrate incubated f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonoglyceride lipase(Homo sapiens (Human))
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50160290(CHEMBL3786806)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant C-terminal His6-tagged human MAGL expressed in Escherichia coli using 2-arachidonoyl-[3H]-glycerol as substrate incubated f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonoglyceride lipase(Homo sapiens (Human))
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50160289(CHEMBL3785148)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant C-terminal His6-tagged human MAGL expressed in Escherichia coli using 2-arachidonoyl-[3H]-glycerol as substrate incubated f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonoglyceride lipase(Homo sapiens (Human))
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50160288(CHEMBL3787437)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant C-terminal His6-tagged human MAGL expressed in Escherichia coli using 2-arachidonoyl-[3H]-glycerol as substrate incubated f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonoglyceride lipase(Homo sapiens (Human))
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50160286(CHEMBL3787456)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of recombinant C-terminal His6-tagged human MAGL expressed in Escherichia coli using 2-arachidonoyl-[3H]-glycerol as substrate incubated f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Mus musculus (mouse))
University Of Siena

Curated by ChEMBL
LigandPNGBDBM60622(BDBM50300355 | US11753371, Compound JZL-184 | US91...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of FAAH in mouse brain membrane using [13C]oleamide as substrate by LC-MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50160278(CHEMBL3786142)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of FAAH in rat brain membranes using using N-arachidonoyl-[14C]-ethanolamine as substrate assessed as reduction in [14C]ethanolamine produ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50160281(CHEMBL3787592)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of FAAH in rat brain membranes using using N-arachidonoyl-[14C]-ethanolamine as substrate assessed as reduction in [14C]ethanolamine produ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Institut De Recherche Biom£Dicale Des Arm£Es

Curated by ChEMBL
LigandPNGBDBM50020522(1-(((4-carbamoylpyridinium-1-yl)methoxy)methyl)-2-...)
Affinity DataIC50:  5.50E+4nMAssay Description:Inhibition of recombinant His-TEV-tagged human AChE expressed in CHO-K1 cells using acetylthiocholine iodide as substrate measured for 6 mins by Ellm...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Institut De Recherche Biom£Dicale Des Arm£Es

Curated by ChEMBL
LigandPNGBDBM50586078(CHEMBL5084128)
Affinity DataIC50:  1.40E+5nMAssay Description:Inhibition of recombinant His-TEV-tagged human AChE expressed in CHO-K1 cells using acetylthiocholine iodide as substrate measured for 6 mins by Ellm...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Institut De Recherche Biom£Dicale Des Arm£Es

Curated by ChEMBL
LigandPNGBDBM50239371(Atnaa | CHEBI:8354 | Duodote | Pralidoxime)
Affinity DataIC50:  5.60E+5nMAssay Description:Inhibition of recombinant His-TEV-tagged human AChE expressed in CHO-K1 cells using acetylthiocholine iodide as substrate measured for 6 mins by Ellm...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Institut De Recherche Biom£Dicale Des Arm£Es

Curated by ChEMBL
LigandPNGBDBM50586080(CHEMBL5088176)
Affinity DataIC50:  5.80E+5nMAssay Description:Inhibition of recombinant His-TEV-tagged human AChE expressed in CHO-K1 cells using acetylthiocholine iodide as substrate measured for 6 mins by Ellm...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Institut De Recherche Biom£Dicale Des Arm£Es

Curated by ChEMBL
LigandPNGBDBM50333779(1,3-Bis(4-(Hydroxyimino-methyl)-pyridinium)-2-oxap...)
Affinity DataIC50:  6.40E+5nMAssay Description:Inhibition of recombinant His-TEV-tagged human AChE expressed in CHO-K1 cells using acetylthiocholine iodide as substrate measured for 6 mins by Ellm...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Institut De Recherche Biom£Dicale Des Arm£Es

Curated by ChEMBL
LigandPNGBDBM50586079(CHEMBL5069796)
Affinity DataIC50:  1.60E+6nMAssay Description:Inhibition of recombinant His-TEV-tagged human AChE expressed in CHO-K1 cells using acetylthiocholine iodide as substrate measured for 6 mins by Ellm...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed