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Found 39 with Last Name = 'dupuy' and Initial = 'a'
TargetTryptase beta-2(Homo sapiens (Human))
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50167517(CHEMBL191546 | [4-(3-Aminomethyl-phenyl)-piperidin...)
Affinity DataKi:  32nMAssay Description:In vitro inhibitory activity against tryptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase beta-2(Homo sapiens (Human))
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50167534(CHEMBL370284 | [4-(3-Aminomethyl-phenyl)-piperidin...)
Affinity DataKi:  41nMAssay Description:In vitro inhibitory activity against tryptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase beta-2(Homo sapiens (Human))
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50167531(CHEMBL365527 | [4-(3-Aminomethyl-phenyl)-piperidin...)
Affinity DataKi:  41nMAssay Description:In vitro inhibitory activity against tryptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase beta-2(Homo sapiens (Human))
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50167524(CHEMBL192963 | [4-(3-Aminomethyl-phenyl)-piperidin...)
Affinity DataKi:  49nMAssay Description:In vitro inhibitory activity against tryptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase beta-2(Homo sapiens (Human))
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50167525(CHEMBL193514 | [4-(3-Aminomethyl-phenyl)-piperidin...)
Affinity DataKi:  57nMAssay Description:In vitro inhibitory activity against tryptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase beta-2(Homo sapiens (Human))
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50167530(CHEMBL189101 | [4-(3-Aminomethyl-phenyl)-piperidin...)
Affinity DataKi:  61nMAssay Description:In vitro inhibitory activity against tryptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase beta-2(Homo sapiens (Human))
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50167514(CHEMBL370463 | [4-(3-Aminomethyl-phenyl)-piperidin...)
Affinity DataKi:  68nMAssay Description:Binding affinity of compound towards Factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase beta-2(Homo sapiens (Human))
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50167520(CHEMBL365148 | [4-(3-Aminomethyl-phenyl)-piperidin...)
Affinity DataKi:  101nMAssay Description:In vitro inhibitory activity against tryptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase beta-2(Homo sapiens (Human))
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50167526(CHEMBL365189 | [4-(3-Aminomethyl-phenyl)-piperidin...)
Affinity DataKi:  116nMAssay Description:In vitro inhibitory activity against tryptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase beta-2(Homo sapiens (Human))
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50167522(CHEMBL372028 | [4-(3-Aminomethyl-phenyl)-piperidin...)
Affinity DataKi:  124nMAssay Description:In vitro inhibitory activity against tryptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase beta-2(Homo sapiens (Human))
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50167521(CHEMBL364661 | [4-(3-Aminomethyl-phenyl)-piperidin...)
Affinity DataKi:  125nMAssay Description:In vitro inhibitory activity against tryptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase beta-2(Homo sapiens (Human))
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50167511(CHEMBL189531 | [4-(3-Aminomethyl-phenyl)-piperidin...)
Affinity DataKi:  128nMAssay Description:In vitro inhibitory activity against tryptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase beta-2(Homo sapiens (Human))
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM16127(2,2 -methanediylbis(1H-benzimidazole-6-carboximida...)
Affinity DataKi:  140nMAssay Description:In vitro inhibitory activity against tryptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase beta-2(Homo sapiens (Human))
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50167523(CHEMBL190103 | [4-(3-Aminomethyl-phenyl)-piperidin...)
Affinity DataKi:  141nMAssay Description:In vitro inhibitory activity against tryptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase beta-2(Homo sapiens (Human))
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50167535(CHEMBL191007 | [4-(3-Aminomethyl-phenyl)-piperidin...)
Affinity DataKi:  155nMAssay Description:In vitro inhibitory activity against tryptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase beta-2(Homo sapiens (Human))
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50167533(CHEMBL435694 | [4-(3-Aminomethyl-phenyl)-piperidin...)
Affinity DataKi:  162nMAssay Description:In vitro inhibitory activity against tryptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase beta-2(Homo sapiens (Human))
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50167510(CHEMBL361040 | [4-(3-Aminomethyl-phenyl)-piperidin...)
Affinity DataKi:  185nMAssay Description:In vitro inhibitory activity against tryptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase beta-2(Homo sapiens (Human))
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50167529(CHEMBL372912 | [4-(3-Aminomethyl-phenyl)-piperidin...)
Affinity DataKi:  197nMAssay Description:In vitro inhibitory activity against tryptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase beta-2(Homo sapiens (Human))
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50167515(1-{3-[4-(3-Aminomethyl-phenyl)-piperidine-1-carbon...)
Affinity DataKi:  240nMAssay Description:In vitro inhibitory activity against tryptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase beta-2(Homo sapiens (Human))
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50167513(CHEMBL192214 | [4-(3-Aminomethyl-phenyl)-piperidin...)
Affinity DataKi:  246nMAssay Description:In vitro inhibitory activity against tryptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase beta-2(Homo sapiens (Human))
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50167528(CHEMBL436537 | [4-(3-Aminomethyl-phenyl)-piperidin...)
Affinity DataKi:  290nMAssay Description:In vitro inhibitory activity against tryptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase beta-2(Homo sapiens (Human))
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50167519(CHEMBL190135 | [4-(3-Aminomethyl-phenyl)-piperidin...)
Affinity DataKi:  310nMAssay Description:In vitro inhibitory activity against tryptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase beta-2(Homo sapiens (Human))
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50167527(CHEMBL189983 | [4-(3-Aminomethyl-phenyl)-piperidin...)
Affinity DataKi:  368nMAssay Description:In vitro inhibitory activity against tryptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase beta-2(Homo sapiens (Human))
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50167518(CHEMBL189372 | [4-(3-Aminomethyl-phenyl)-piperidin...)
Affinity DataKi:  373nMAssay Description:In vitro inhibitory activity against tryptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase beta-2(Homo sapiens (Human))
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50167516(CHEMBL191731 | [4-(3-Aminomethyl-phenyl)-piperidin...)
Affinity DataKi:  497nMAssay Description:In vitro inhibitory activity against tryptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase beta-2(Homo sapiens (Human))
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50167512(CHEMBL188104 | [4-(3-Aminomethyl-phenyl)-piperidin...)
Affinity DataKi: >2.00E+4nMAssay Description:In vitro inhibitory activity against tryptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase beta-2(Homo sapiens (Human))
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50167532(CHEMBL191072 | [4-(3-Aminomethyl-phenyl)-piperidin...)
Affinity DataKi: >2.00E+4nMAssay Description:In vitro inhibitory activity against tryptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Sanofi-Aventis Research And Development

Curated by ChEMBL
LigandPNGBDBM50357454(CHEMBL1917878)
Affinity DataIC50:  30nMAssay Description:Inhibition of HSP90beta in human SKBR3 cells assessed as down regulation of HER2 expression levels after 24 hrs by FACS analysisMore data for this Ligand-Target Pair
TargetTryptase beta-2(Homo sapiens (Human))
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50167514(CHEMBL370463 | [4-(3-Aminomethyl-phenyl)-piperidin...)
Affinity DataIC50:  68nMAssay Description:In vitro inhibitory activity against Factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Sanofi-Aventis Research And Development

Curated by ChEMBL
LigandPNGBDBM50357460(CHEMBL1917729)
Affinity DataIC50:  900nMAssay Description:Inhibition of HSP90beta in human SKBR3 cells assessed as down regulation of HER2 expression levels after 24 hrs by FACS analysisMore data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Sanofi-Aventis Research And Development

Curated by ChEMBL
LigandPNGBDBM50357459(CHEMBL1917728)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of HSP90beta in human SKBR3 cells assessed as down regulation of HER2 expression levels after 24 hrs by FACS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Sanofi-Aventis Research And Development

Curated by ChEMBL
LigandPNGBDBM50357458(CHEMBL1917727)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of HSP90beta in human SKBR3 cells assessed as down regulation of HER2 expression levels after 24 hrs by FACS analysisMore data for this Ligand-Target Pair
TargetTryptase beta-2(Homo sapiens (Human))
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50167514(CHEMBL370463 | [4-(3-Aminomethyl-phenyl)-piperidin...)
Affinity DataIC50:  3.69E+3nMAssay Description:Inhibitory concentration of the compound against alpha tryptase was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Sanofi-Aventis Research And Development

Curated by ChEMBL
LigandPNGBDBM50357461(CHEMBL1917723)
Affinity DataIC50:  7.60E+3nMAssay Description:Inhibition of human Hsp90beta after overnight incubation by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Sanofi-Aventis Research And Development

Curated by ChEMBL
LigandPNGBDBM50357456(CHEMBL1917725)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of HSP90beta in human SKBR3 cells assessed as down regulation of HER2 expression levels after 24 hrs by FACS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Sanofi-Aventis Research And Development

Curated by ChEMBL
LigandPNGBDBM50357455(CHEMBL1917724)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of HSP90beta in human SKBR3 cells assessed as down regulation of HER2 expression levels after 24 hrs by FACS analysisMore data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Sanofi-Aventis Research And Development

Curated by ChEMBL
LigandPNGBDBM50357457(CHEMBL1917726)
Affinity DataIC50:  5.00E+4nMAssay Description:Inhibition of HSP90beta in human SKBR3 cells assessed as down regulation of HER2 expression levels after 24 hrs by FACS analysisMore data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Sanofi-Aventis Research And Development

Curated by ChEMBL
LigandPNGBDBM50357454(CHEMBL1917878)
Affinity DataKd:  0.350nMAssay Description:Binding affinity to human Hsp90beta after overnight incubation by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Sanofi-Aventis Research And Development

Curated by ChEMBL
LigandPNGBDBM15359((4E,6Z,8S,9S,10E,12S,13R,14S,16R)-13-hydroxy-8,14-...)
Affinity DataKd:  7.30nMAssay Description:Binding affinity to human Hsp90beta after overnight incubation by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed