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Found 305 with Last Name = 'gelin' and Initial = 'm'
TargetAminopeptidase N(Sus scrofa (Pig))
Universit£

Curated by ChEMBL
LigandPNGBDBM50353018(CHEMBL1821980 | CHEMBL1852660)
Affinity DataKi:  0.0600nMAssay Description:Inhibition of pig APN using L-leucine-p-nitroanilide as substrate measured every 10 mins for 2 hrs by spectriphotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAminopeptidase N(Mus musculus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50353018(CHEMBL1821980 | CHEMBL1852660)
Affinity DataKi:  0.200nMAssay Description:Inhibition of mouse APN using L-leucine-p-nitroanilide as substrate measured every 10 mins for 2 hrs by spectriphotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAminopeptidase N(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50353018(CHEMBL1821980 | CHEMBL1852660)
Affinity DataKi:  0.350nMAssay Description:Inhibition of human APN using L-leucine-p-nitroanilide as substrate measured every 10 mins for 2 hrs by spectriphotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAminopeptidase N(Sus scrofa (Pig))
Universit£

Curated by ChEMBL
LigandPNGBDBM50353016(CHEMBL1821978)
Affinity DataKi:  7nMAssay Description:Inhibition of pig APN using L-leucine-p-nitroanilide as substrate measured every 10 mins for 2 hrs by spectriphotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAminopeptidase N(Mus musculus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50353016(CHEMBL1821978)
Affinity DataKi:  10nMAssay Description:Inhibition of mouse APN using L-leucine-p-nitroanilide as substrate measured every 10 mins for 2 hrs by spectriphotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAminopeptidase N(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50353016(CHEMBL1821978)
Affinity DataKi:  11nMAssay Description:Inhibition of human APN using L-leucine-p-nitroanilide as substrate measured every 10 mins for 2 hrs by spectriphotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAminopeptidase N(Sus scrofa (Pig))
Universit£

Curated by ChEMBL
LigandPNGBDBM50336495(7-Amino-5,7,8,9-tetrahydro-benzocyclohepten-6-one,...)
Affinity DataKi:  1.00E+3nMAssay Description:Inhibition of pig APN using L-leucine-p-nitroanilide as substrate measured every 10 mins for 2 hrs by spectriphotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAminopeptidase N(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50336495(7-Amino-5,7,8,9-tetrahydro-benzocyclohepten-6-one,...)
Affinity DataKi:  2.00E+3nMAssay Description:Inhibition of human APN using L-leucine-p-nitroanilide as substrate measured every 10 mins for 2 hrs by spectriphotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAminopeptidase N(Mus musculus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50336495(7-Amino-5,7,8,9-tetrahydro-benzocyclohepten-6-one,...)
Affinity DataKi:  2.00E+3nMAssay Description:Inhibition of mouse APN using L-leucine-p-nitroanilide as substrate measured every 10 mins for 2 hrs by spectriphotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD kinase(Staphylococcus aureus)
Institut Curie

US Patent
LigandPNGBDBM141970(US8927520, 19)
Affinity DataKi:  5.00E+3nMAssay Description:For inhibitor assays, IC50 was determined, in the presence of 1 mM NAD and 4 mM ATP (for LmNADK1) or 2 mM ATP (for SaNADK). Dixon plots were used to ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNAD kinase 1(Listeria monocytogenes)
Institut Curie

US Patent
LigandPNGBDBM141970(US8927520, 19)
Affinity DataKi:  1.00E+4nMAssay Description:For inhibitor assays, IC50 was determined, in the presence of 1 mM NAD and 4 mM ATP (for LmNADK1) or 2 mM ATP (for SaNADK). Dixon plots were used to ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNAD kinase(Staphylococcus aureus)
Institut Curie

US Patent
LigandPNGBDBM141971(US8927520, 22)
Affinity DataKi:  1.50E+4nMAssay Description:For inhibitor assays, IC50 was determined, in the presence of 1 mM NAD and 4 mM ATP (for LmNADK1) or 2 mM ATP (for SaNADK). Dixon plots were used to ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNAD kinase 1(Listeria monocytogenes)
Institut Curie

US Patent
LigandPNGBDBM141971(US8927520, 22)
Affinity DataKi:  2.00E+4nMAssay Description:For inhibitor assays, IC50 was determined, in the presence of 1 mM NAD and 4 mM ATP (for LmNADK1) or 2 mM ATP (for SaNADK). Dixon plots were used to ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNAD kinase(Homo sapiens (Human))
France Cnrs

Curated by ChEMBL
LigandPNGBDBM50208878(CHEMBL3883415)
Affinity DataKi:  2.00E+4nMAssay Description:Inhibition of human NADK expressed in Escherichia coli BL21(DE3) assessed as reduction in NADP production using NAD as substrate by glucose-6-phospha...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD kinase 1(Listeria monocytogenes)
Institut Curie

US Patent
LigandPNGBDBM141969(US8927520, 17)
Affinity DataKi:  3.00E+4nMAssay Description:For inhibitor assays, IC50 was determined, in the presence of 1 mM NAD and 4 mM ATP (for LmNADK1) or 2 mM ATP (for SaNADK). Dixon plots were used to ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNAD kinase(Staphylococcus aureus)
Institut Curie

US Patent
LigandPNGBDBM141969(US8927520, 17)
Affinity DataKi:  5.00E+4nMAssay Description:For inhibitor assays, IC50 was determined, in the presence of 1 mM NAD and 4 mM ATP (for LmNADK1) or 2 mM ATP (for SaNADK). Dixon plots were used to ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNAD kinase(Homo sapiens (Human))
France Cnrs

Curated by ChEMBL
LigandPNGBDBM50208780(CHEMBL3884180)
Affinity DataKi:  5.50E+4nMAssay Description:Inhibition of human NADK expressed in Escherichia coli BL21(DE3) assessed as reduction in NADP production using NAD as substrate by glucose-6-phospha...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD kinase(Homo sapiens (Human))
France Cnrs

Curated by ChEMBL
LigandPNGBDBM50208778(CHEMBL3885397)
Affinity DataKi:  6.50E+4nMAssay Description:Inhibition of human NADK expressed in Escherichia coli BL21(DE3) assessed as reduction in NADP production using NAD as substrate by glucose-6-phospha...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD kinase(Homo sapiens (Human))
France Cnrs

Curated by ChEMBL
LigandPNGBDBM50208802(CHEMBL3885465)
Affinity DataKi:  8.00E+4nMAssay Description:Inhibition of human NADK expressed in Escherichia coli BL21(DE3) assessed as reduction in NADP production using NAD as substrate by glucose-6-phospha...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD kinase(Homo sapiens (Human))
France Cnrs

Curated by ChEMBL
LigandPNGBDBM50208739(CHEMBL3885207)
Affinity DataKi:  8.00E+4nMAssay Description:Inhibition of human NADK expressed in Escherichia coli BL21(DE3) assessed as reduction in NADP production using NAD as substrate by glucose-6-phospha...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD kinase(Homo sapiens (Human))
France Cnrs

Curated by ChEMBL
LigandPNGBDBM50208736(CHEMBL3883373)
Affinity DataKi:  1.30E+5nMAssay Description:Inhibition of human NADK expressed in Escherichia coli BL21(DE3) assessed as reduction in NADP production using NAD as substrate by glucose-6-phospha...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD kinase(Homo sapiens (Human))
France Cnrs

Curated by ChEMBL
LigandPNGBDBM50208741(CHEMBL3883614)
Affinity DataKi:  1.30E+5nMAssay Description:Inhibition of human NADK expressed in Escherichia coli BL21(DE3) assessed as reduction in NADP production using NAD as substrate by glucose-6-phospha...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD kinase(Homo sapiens (Human))
France Cnrs

Curated by ChEMBL
LigandPNGBDBM50208904(CHEMBL3884876)
Affinity DataKi:  1.40E+5nMAssay Description:Inhibition of human NADK expressed in Escherichia coli BL21(DE3) assessed as reduction in NADP production using NAD as substrate by glucose-6-phospha...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD kinase(Homo sapiens (Human))
France Cnrs

Curated by ChEMBL
LigandPNGBDBM50208740(CHEMBL3885345)
Affinity DataKi:  1.40E+5nMAssay Description:Inhibition of human NADK expressed in Escherichia coli BL21(DE3) assessed as reduction in NADP production using NAD as substrate by glucose-6-phospha...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD kinase(Homo sapiens (Human))
France Cnrs

Curated by ChEMBL
LigandPNGBDBM50208805(CHEMBL3883397)
Affinity DataKi:  1.40E+5nMAssay Description:Inhibition of human NADK expressed in Escherichia coli BL21(DE3) assessed as reduction in NADP production using NAD as substrate by glucose-6-phospha...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD kinase(Homo sapiens (Human))
France Cnrs

Curated by ChEMBL
LigandPNGBDBM50208745(CHEMBL3884239)
Affinity DataKi:  1.40E+5nMAssay Description:Inhibition of human NADK expressed in Escherichia coli BL21(DE3) assessed as reduction in NADP production using NAD as substrate by glucose-6-phospha...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD kinase(Homo sapiens (Human))
France Cnrs

Curated by ChEMBL
LigandPNGBDBM50208743(CHEMBL3884081)
Affinity DataKi:  1.50E+5nMAssay Description:Inhibition of human NADK expressed in Escherichia coli BL21(DE3) assessed as reduction in NADP production using NAD as substrate by glucose-6-phospha...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD kinase(Homo sapiens (Human))
France Cnrs

Curated by ChEMBL
LigandPNGBDBM50208737(CHEMBL3884746)
Affinity DataKi:  1.60E+5nMAssay Description:Inhibition of human NADK expressed in Escherichia coli BL21(DE3) assessed as reduction in NADP production using NAD as substrate by glucose-6-phospha...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD kinase(Homo sapiens (Human))
France Cnrs

Curated by ChEMBL
LigandPNGBDBM50208779(CHEMBL3884775)
Affinity DataKi:  1.60E+5nMAssay Description:Inhibition of human NADK expressed in Escherichia coli BL21(DE3) assessed as reduction in NADP production using NAD as substrate by glucose-6-phospha...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD kinase(Homo sapiens (Human))
France Cnrs

Curated by ChEMBL
LigandPNGBDBM50208795(CHEMBL3885356)
Affinity DataKi:  1.80E+5nMAssay Description:Inhibition of human NADK expressed in Escherichia coli BL21(DE3) assessed as reduction in NADP production using NAD as substrate by glucose-6-phospha...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD kinase(Homo sapiens (Human))
France Cnrs

Curated by ChEMBL
LigandPNGBDBM50208735(CHEMBL3884857)
Affinity DataKi:  2.00E+5nMAssay Description:Inhibition of human NADK expressed in Escherichia coli BL21(DE3) assessed as reduction in NADP production using NAD as substrate by glucose-6-phospha...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD kinase(Homo sapiens (Human))
France Cnrs

Curated by ChEMBL
LigandPNGBDBM50208774(CHEMBL3885310)
Affinity DataKi:  2.10E+5nMAssay Description:Inhibition of human NADK expressed in Escherichia coli BL21(DE3) assessed as reduction in NADP production using NAD as substrate by glucose-6-phospha...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD kinase(Homo sapiens (Human))
France Cnrs

Curated by ChEMBL
LigandPNGBDBM50208874(CHEMBL3883624)
Affinity DataKi:  2.20E+5nMAssay Description:Inhibition of human NADK expressed in Escherichia coli BL21(DE3) assessed as reduction in NADP production using NAD as substrate by glucose-6-phospha...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD kinase(Homo sapiens (Human))
France Cnrs

Curated by ChEMBL
LigandPNGBDBM50208781(CHEMBL3883763)
Affinity DataKi:  2.30E+5nMAssay Description:Inhibition of human NADK expressed in Escherichia coli BL21(DE3) assessed as reduction in NADP production using NAD as substrate by glucose-6-phospha...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD kinase(Homo sapiens (Human))
France Cnrs

Curated by ChEMBL
LigandPNGBDBM50208773(CHEMBL3884901)
Affinity DataKi:  2.50E+5nMAssay Description:Inhibition of human NADK expressed in Escherichia coli BL21(DE3) assessed as reduction in NADP production using NAD as substrate by glucose-6-phospha...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD kinase(Homo sapiens (Human))
France Cnrs

Curated by ChEMBL
LigandPNGBDBM50208775(CHEMBL3884119)
Affinity DataKi:  3.00E+5nMAssay Description:Inhibition of human NADK expressed in Escherichia coli BL21(DE3) assessed as reduction in NADP production using NAD as substrate by glucose-6-phospha...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD kinase(Homo sapiens (Human))
France Cnrs

Curated by ChEMBL
LigandPNGBDBM50208742(CHEMBL3884982)
Affinity DataKi:  3.30E+5nMAssay Description:Inhibition of human NADK expressed in Escherichia coli BL21(DE3) assessed as reduction in NADP production using NAD as substrate by glucose-6-phospha...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD kinase(Homo sapiens (Human))
France Cnrs

Curated by ChEMBL
LigandPNGBDBM50208734(CHEMBL3883980)
Affinity DataKi:  3.35E+5nMAssay Description:Inhibition of human NADK expressed in Escherichia coli BL21(DE3) assessed as reduction in NADP production using NAD as substrate by glucose-6-phospha...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD kinase(Homo sapiens (Human))
France Cnrs

Curated by ChEMBL
LigandPNGBDBM50208738(CHEMBL3885227)
Affinity DataKi:  3.50E+5nMAssay Description:Inhibition of human NADK expressed in Escherichia coli BL21(DE3) assessed as reduction in NADP production using NAD as substrate by glucose-6-phospha...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD kinase(Homo sapiens (Human))
France Cnrs

Curated by ChEMBL
LigandPNGBDBM50208744(CHEMBL3885137)
Affinity DataKi:  3.50E+5nMAssay Description:Inhibition of human NADK expressed in Escherichia coli BL21(DE3) assessed as reduction in NADP production using NAD as substrate by glucose-6-phospha...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD kinase(Homo sapiens (Human))
France Cnrs

Curated by ChEMBL
LigandPNGBDBM50208776(CHEMBL3883970)
Affinity DataKi:  4.25E+5nMAssay Description:Inhibition of human NADK expressed in Escherichia coli BL21(DE3) assessed as reduction in NADP production using NAD as substrate by glucose-6-phospha...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD kinase(Homo sapiens (Human))
France Cnrs

Curated by ChEMBL
LigandPNGBDBM50208777(CHEMBL3883775)
Affinity DataKi:  5.25E+5nMAssay Description:Inhibition of human NADK expressed in Escherichia coli BL21(DE3) assessed as reduction in NADP production using NAD as substrate by glucose-6-phospha...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD kinase(Homo sapiens (Human))
France Cnrs

Curated by ChEMBL
LigandPNGBDBM50208905(CHEMBL3884652)
Affinity DataKi:  7.75E+5nMAssay Description:Inhibition of human NADK expressed in Escherichia coli BL21(DE3) assessed as reduction in NADP production using NAD as substrate by glucose-6-phospha...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Cnrs

Curated by ChEMBL
LigandPNGBDBM50428286(DABRAFENIB | GSK2118436A)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of N-terminal His-tagged human B-Raf kinase domain (448 to 723 residues) expressed in Escherichia coli BL21 (DE3) by Lanthascreen assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Cnrs

Curated by ChEMBL
LigandPNGBDBM50602851(CHEMBL5189539)
Affinity DataIC50:  1.70nMAssay Description:Inhibition of N-terminal His-tagged human recombinant B-Raf V600E mutant (448 to 723 residues) expressed in Escherichia coli BL21 (DE3) by Lanthascre...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Cnrs

Curated by ChEMBL
LigandPNGBDBM50602852(CHEMBL5201169)
Affinity DataIC50:  1.70nMAssay Description:Inhibition of N-terminal His-tagged human recombinant B-Raf V600E mutant (448 to 723 residues) expressed in Escherichia coli BL21 (DE3) by Lanthascre...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Cnrs

Curated by ChEMBL
LigandPNGBDBM50602855(CHEMBL5176494)
Affinity DataIC50:  2nMAssay Description:Inhibition of N-terminal His-tagged human recombinant B-Raf V600E mutant (448 to 723 residues) expressed in Escherichia coli BL21 (DE3) by Lanthascre...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Cnrs

Curated by ChEMBL
LigandPNGBDBM50602850(CHEMBL5203353)
Affinity DataIC50:  2.10nMAssay Description:Inhibition of N-terminal His-tagged human recombinant B-Raf V600E mutant (448 to 723 residues) expressed in Escherichia coli BL21 (DE3) by Lanthascre...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Cnrs

Curated by ChEMBL
LigandPNGBDBM50602854(CHEMBL5202550)
Affinity DataIC50:  3.60nMAssay Description:Inhibition of N-terminal His-tagged human recombinant B-Raf V600E mutant (448 to 723 residues) expressed in Escherichia coli BL21 (DE3) by Lanthascre...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Cnrs

Curated by ChEMBL
LigandPNGBDBM50602856(CHEMBL5183233)
Affinity DataIC50:  4.40nMAssay Description:Inhibition of N-terminal His-tagged human recombinant B-Raf V600E mutant (448 to 723 residues) expressed in Escherichia coli BL21 (DE3) by Lanthascre...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
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