Affinity DataKi: 0.0240nMAssay Description:Binding affinity for E. coli Dihydrofolate reductaseMore data for this Ligand-Target Pair
Affinity DataKi: 0.0350nMAssay Description:Binding affinity for E. coli Dihydrofolate reductaseMore data for this Ligand-Target Pair
Affinity DataKi: 0.0500nMAssay Description:Binding affinity for E. coli Dihydrofolate reductaseMore data for this Ligand-Target Pair
Affinity DataKi: 0.0660nMAssay Description:Binding affinity for E. coli Dihydrofolate reductaseMore data for this Ligand-Target Pair
Affinity DataKi: 0.370nMAssay Description:Binding affinity for E. coli Dihydrofolate reductaseMore data for this Ligand-Target Pair
Affinity DataKi: 0.398nMAssay Description:Displacement of [3H]WAY-100635 from human cloned 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.398nMAssay Description:Displacement of [3H]5-HT from human cloned 5HT1D receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.470nMAssay Description:Displacement of [3H]diprenorphine from human cloned mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.470nMAssay Description:Binding affinity for E. coli Dihydrofolate reductaseMore data for this Ligand-Target Pair
TargetKinesin-like protein KIF11(Homo sapiens (Human))
The Beatson Institute For Cancer Research
Curated by ChEMBL
The Beatson Institute For Cancer Research
Curated by ChEMBL
Affinity DataKi: 0.5nMAssay Description:Inhibition of MT-stimulated human N-terminal His6-tagged Eg5 (1 to 368 amino acid residues) motor domain ATPase activity expressed in Escherichia col...More data for this Ligand-Target Pair
Affinity DataKi: 0.501nMAssay Description:Binding affinity for human 5-hydroxytryptamine 2C receptor expressed in HEK 293 cells using [3H]mesulergineMore data for this Ligand-Target Pair
Affinity DataKi: 0.501nMAssay Description:Displacement of [3H]WAY-100635 from human cloned 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.570nM ΔG°: -52.8kJ/mole IC50: 0.530nMpH: 7.8 T: 2°CAssay Description:The receptor binding method (DeHaven and DeHaven-Hudkins, 1998) was a modification of the method of Raynor et al. (1994). More data for this Ligand-Target Pair
Affinity DataKi: 0.620nMAssay Description:Displacement of [3H]diprenorphine from human cloned mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.620nMAssay Description:Displacement of [3H]diprenorphine from human cloned mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.631nMAssay Description:Binding affinity for human 5-hydroxytryptamine 2C receptor expressed in HEK 293 cells using [3H]mesulergineMore data for this Ligand-Target Pair
Affinity DataKi: 0.760nMAssay Description:Binding affinity for E. coli Dihydrofolate reductaseMore data for this Ligand-Target Pair
Affinity DataKi: 0.794nMAssay Description:Binding affinity for human 5-hydroxytryptamine 2C receptor expressed in HEK 293 cells using [3H]mesulergineMore data for this Ligand-Target Pair
Affinity DataKi: 0.794nMAssay Description:Displacement of [3H]WAY-100635 from human cloned 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.794nMAssay Description:Displacement of [3H]5-HT from human cloned 5HT1B receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.794nMAssay Description:Displacement of [3H]5-HT from human cloned 5HT1D receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.860nMAssay Description:Binding affinity for E. coli Dihydrofolate reductaseMore data for this Ligand-Target Pair
Affinity DataKi: 0.900nMAssay Description:Antagonist activity against human cloned mu opioid receptor expressed in CHO cells assessed as inhibition of loperamide-stimulated [35S]GTP-gamma-S b...More data for this Ligand-Target Pair
Affinity DataKi: 0.980nMAssay Description:Displacement of [3H]diprenorphine from human cloned mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Binding affinity for human 5-hydroxytryptamine 2C receptor expressed in HEK 293 cells using [3H]mesulergineMore data for this Ligand-Target Pair
Affinity DataKi: >1nMAssay Description:Agonist activity at rat 5HT1A receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Binding affinity for human 5-hydroxytryptamine 2C receptor expressed in HEK 293 cells using [3H]mesulergineMore data for this Ligand-Target Pair
Affinity DataKi: >1nMAssay Description:Agonist activity at rat 5HT1A receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Displacement of [3H]diprenorphine from human cloned mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Binding affinity for human 5-hydroxytryptamine 2C receptor expressed in HEK 293 cells using [3H]mesulergineMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Displacement of [3H]diprenorphine from human cloned mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.10nM ΔG°: -51.1kJ/mole IC50: 11nMpH: 7.8 T: 2°CAssay Description:The receptor binding method (DeHaven and DeHaven-Hudkins, 1998) was a modification of the method of Raynor et al. (1994). More data for this Ligand-Target Pair
Affinity DataKi: 1.10nMAssay Description:Displacement of [3H]diprenorphine from human cloned mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetKinesin-like protein KIF11(Homo sapiens (Human))
The Beatson Institute For Cancer Research
Curated by ChEMBL
The Beatson Institute For Cancer Research
Curated by ChEMBL
Affinity DataKi: 1.20nMAssay Description:Inhibition of human N-terminal His6-tagged Eg5 (1 to 368 amino acid residues) motor domain basal ATPase activity expressed in Escherichia coli BL21 (...More data for this Ligand-Target Pair
Affinity DataKi: 1.20nMAssay Description:Displacement of [3H]diprenorphine from human cloned mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.26nMAssay Description:Binding affinity for human 5-hydroxytryptamine 2C receptor expressed in HEK 293 cells using [3H]mesulergineMore data for this Ligand-Target Pair
Affinity DataKi: 1.26nMAssay Description:Binding affinity for human 5-hydroxytryptamine 2C receptor expressed in HEK 293 cells using [3H]mesulergineMore data for this Ligand-Target Pair
Affinity DataKi: 1.30nMAssay Description:Displacement of [3H]diprenorphine from human cloned mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.30nMAssay Description:Binding affinity for E. coli Dihydrofolate reductaseMore data for this Ligand-Target Pair
Affinity DataKi: 1.40nMAssay Description:Displacement of [3H]diprenorphine from human cloned mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.5nMAssay Description:Displacement of [3H]diprenorphine from human cloned mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.58nMAssay Description:Binding affinity for human 5-hydroxytryptamine 2C receptor expressed in HEK 293 cells using [3H]mesulergineMore data for this Ligand-Target Pair
Affinity DataKi: 1.60nMAssay Description:Displacement of [3H]WAY-100635 from human cloned 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.60nMAssay Description:Displacement of [3H]WAY-100635 from human cloned 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.60nMAssay Description:Displacement of [3H]5-HT from human cloned 5HT1D receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.70nMAssay Description:Displacement of [3H]CP55940 from human cloned CB2 receptor by scintillation spectrometryMore data for this Ligand-Target Pair
Affinity DataKi: 1.80nMAssay Description:Displacement of [3H]diprenorphine from human cloned mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.80nMAssay Description:Displacement of [3H]diprenorphine from human cloned mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.80nMAssay Description:Displacement of [3H]diprenorphine from human cloned mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.80nMAssay Description:Displacement of [3H]diprenorphine from human cloned mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair