Compile Data Set for Download or QSAR
maximum 50k data
Found 82 with Last Name = 'gullo' and Initial = 'vp'
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50120316(CHEMBL2367887 | Triterpene Glycoside analogue)
Affinity DataKi:  5.10E+3nMAssay Description:Inhibitory activity of the compound against human CCR5 chemokine receptor (CCR5) expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50120315(CHEMBL2367888 | Triterpene Glycoside analogue)
Affinity DataKi:  3.00E+4nMAssay Description:Inhibitory activity of the compound against human CCR5 chemokine receptor (CCR5) expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50292438(1,-(4-amino-5-oxotridecane-1,13-diyl)diguanidine |...)
Affinity DataIC50:  6nMAssay Description:Displacement of QNB from muscarinic M2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50292438(1,-(4-amino-5-oxotridecane-1,13-diyl)diguanidine |...)
Affinity DataIC50:  7nMAssay Description:Displacement of QNB from muscarinic M1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50292438(1,-(4-amino-5-oxotridecane-1,13-diyl)diguanidine |...)
Affinity DataIC50:  10nMAssay Description:Displacement of QNB from muscarinic M4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50306888(4,6-dimethoxy-3-methyl-1H-pyrazolo[3,4-b]quinoline...)
Affinity DataIC50:  20nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50306874(8-Hydroxy-6H-benzo[f][1,3]dioxolo[4',5':4,5]benzo[...)
Affinity DataIC50:  35nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetT-cell surface glycoprotein CD4(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50123450(CHEMBL3143464 | Chloropeptin I analogue)
Affinity DataIC50:  130nMAssay Description:Inhibitory concentration against CD4-gp120 binding in the absence of fetal bovine serum (FBS); Range is 0.13-0.5 uMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetT-cell surface glycoprotein CD4(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50123449(CHEMBL437996 | Chloropeptin II | ISOCOMPLESTATIN)
Affinity DataIC50:  130nMAssay Description:Inhibitory concentration against CD4-gp120 binding in the absence of fetal bovine serum (FBS); Range is 0.13-0.5 uMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetT-cell surface glycoprotein CD4(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50366855(CHEMBL525803 | Chloropeptin)
Affinity DataIC50:  130nMAssay Description:Inhibitory concentration against CD4-gp120 binding in the absence of fetal bovine serum (FBS); Range is 0.13-0.5 uMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50197834(2,9-dihydroxy-1-methoxydibenzo[cd,f]indol-4(5H)-on...)
Affinity DataIC50:  140nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50197834(2,9-dihydroxy-1-methoxydibenzo[cd,f]indol-4(5H)-on...)
Affinity DataIC50:  140nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50197834(2,9-dihydroxy-1-methoxydibenzo[cd,f]indol-4(5H)-on...)
Affinity DataIC50:  200nMAssay Description:Inhibition of CDC2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50306888(4,6-dimethoxy-3-methyl-1H-pyrazolo[3,4-b]quinoline...)
Affinity DataIC50:  200nMAssay Description:Inhibition of CDC2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50306874(8-Hydroxy-6H-benzo[f][1,3]dioxolo[4',5':4,5]benzo[...)
Affinity DataIC50:  214nMAssay Description:Inhibition of CDC2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50197834(2,9-dihydroxy-1-methoxydibenzo[cd,f]indol-4(5H)-on...)
Affinity DataIC50:  214nMAssay Description:Inhibition of CDC2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50135740(2,3,4,5,6,7,14,15-octahydroxy-13-(5-hydroxy-4-oxo-...)
Affinity DataIC50:  300nMAssay Description:Inhibitory activity of the compound evaluated in the HCV NS3 protease activity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50135739(13-[3,5-dihydroxy-4-(3-phenylpropanoyl)phenoxy]-2,...)
Affinity DataIC50:  800nMAssay Description:Inhibitory activity of the compound evaluated in the HCV NS3 protease assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50292439(CHEMBL479224 | N-(1,13-diguanidino-5-oxotridecan-4...)
Affinity DataIC50:  910nMAssay Description:Displacement of QNB from muscarinic M4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50292439(CHEMBL479224 | N-(1,13-diguanidino-5-oxotridecan-4...)
Affinity DataIC50:  960nMAssay Description:Displacement of QNB from muscarinic M2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50306869(8-Methoxy-6H-benzo[f][1,3]dioxolo[4',5':4,5]benzo[...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50292439(CHEMBL479224 | N-(1,13-diguanidino-5-oxotridecan-4...)
Affinity DataIC50:  1.41E+3nMAssay Description:Displacement of QNB from muscarinic M1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50306874(8-Hydroxy-6H-benzo[f][1,3]dioxolo[4',5':4,5]benzo[...)
Affinity DataIC50:  1.42E+3nMAssay Description:Inhibition of CDK4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50197834(2,9-dihydroxy-1-methoxydibenzo[cd,f]indol-4(5H)-on...)
Affinity DataIC50:  1.42E+3nMAssay Description:Inhibition of CDK4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50197834(2,9-dihydroxy-1-methoxydibenzo[cd,f]indol-4(5H)-on...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of CDK4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50197834(2,9-dihydroxy-1-methoxydibenzo[cd,f]indol-4(5H)-on...)
Affinity DataIC50:  2.14E+3nMAssay Description:Inhibition of Aurora 2 kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50306874(8-Hydroxy-6H-benzo[f][1,3]dioxolo[4',5':4,5]benzo[...)
Affinity DataIC50:  2.14E+3nMAssay Description:Inhibition of AUR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50306877(10-Hydroxy-6H-benzo[f][1,3]dioxolo[4',5':4,5]benzo...)
Affinity DataIC50:  2.15E+3nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Human rhinovirus B)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50135740(2,3,4,5,6,7,14,15-octahydroxy-13-(5-hydroxy-4-oxo-...)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibitory activity of the compound evaluated in the HCV protease binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50306872(9-Hydroxy-8-methoxy-6H-benzo[f][1,3]dioxolo[4',5':...)
Affinity DataIC50:  2.90E+3nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50306888(4,6-dimethoxy-3-methyl-1H-pyrazolo[3,4-b]quinoline...)
Affinity DataIC50:  3.50E+3nMAssay Description:Inhibition of AUR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50197834(2,9-dihydroxy-1-methoxydibenzo[cd,f]indol-4(5H)-on...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of AUR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50475483(CHEMBL2303627)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibitory concentration against human Vascular endothelial growth factor receptor 2More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50153762(3-(4-Methoxy-phenyl)-acrylic acid 2-{(1S,2S)-2-[(S...)
Affinity DataIC50:  5.50E+3nMAssay Description:Inhibition of MIP-1beta ligand of chemokine receptor 5 induced calcium signal in U-87-CCR5 cells by calcium mobilization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50306866(3,4,8-trihydroxy-10-nitrophenanthrene-1-carboxylic...)
Affinity DataIC50:  5.70E+3nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50153762(3-(4-Methoxy-phenyl)-acrylic acid 2-{(1S,2S)-2-[(S...)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibition of MIP-1beta ligand of chemokine receptor 5 induced calcium signal in U-87-CCR5 cells by calcium mobilization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50153764((Z)-1-((1S,2S)-2-((S)-hydroxy((R)-6-oxo-3,6-dihydr...)
Affinity DataIC50:  7.20E+3nMAssay Description:Inhibition of MIP-1beta ligand of chemokine receptor 5 induced calcium signal in U-87-CCR5 cells by calcium mobilization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50153762(3-(4-Methoxy-phenyl)-acrylic acid 2-{(1S,2S)-2-[(S...)
Affinity DataIC50:  8.70E+3nMAssay Description:Inhibition of 50% of RANTES co-receptor of chemokine receptor 5 induced calcium signal in U-87-CCR5 cells by calcium mobilization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50153762(3-(4-Methoxy-phenyl)-acrylic acid 2-{(1S,2S)-2-[(S...)
Affinity DataIC50:  8.80E+3nMAssay Description:Inhibition of MIP-1alpha ligand of chemokine receptor 5 induced calcium signal in U-87-CCR5 cells by calcium mobilization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50306888(4,6-dimethoxy-3-methyl-1H-pyrazolo[3,4-b]quinoline...)
Affinity DataIC50:  9.00E+3nMAssay Description:Inhibition of CDK4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50153764((Z)-1-((1S,2S)-2-((S)-hydroxy((R)-6-oxo-3,6-dihydr...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of MIP-1alpha ligand of chemokine receptor 5 induced calcium signal in U-87-CCR5 cells by calcium mobilization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50153764((Z)-1-((1S,2S)-2-((S)-hydroxy((R)-6-oxo-3,6-dihydr...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of RANTES co-receptor of chemokine receptor 5 induced calcium signal in U-87-CCR5 cells by calcium mobilization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50306911(8-((2S,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-hydroxymeth...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50153762(3-(4-Methoxy-phenyl)-acrylic acid 2-{(1S,2S)-2-[(S...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of MIP-1alpha ligand of chemokine receptor 5 induced calcium signal in U-87-CCR5 cells by calcium mobilization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50306884(6-chloro-1,2-dihydroxy-7-methoxydibenzo[cd,f]indol...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50153762(3-(4-Methoxy-phenyl)-acrylic acid 2-{(1S,2S)-2-[(S...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of RANTES co-receptor of chemokine receptor 5 induced calcium signal in U-87-CCR5 cells by calcium mobilization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50306888(4,6-dimethoxy-3-methyl-1H-pyrazolo[3,4-b]quinoline...)
Affinity DataIC50:  1.14E+4nMAssay Description:Inhibition of AKTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50306863(3,4-dihydroxy-10-nitrophenanthrene-1-carboxylic ac...)
Affinity DataIC50:  1.34E+4nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50306868(6H-Benzo[f][1,3]dioxolo[4',5':4,5]benzo[1,2,3-cd]i...)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50306861(CHEMBL601026 | aristolochic acid III)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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