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Found 171 with Last Name = 'pals' and Initial = 'dt'
TargetRenin(Homo sapiens (Human))
Upjohn

Curated by ChEMBL
LigandPNGBDBM50022835(Ac-Ftr-Pro-Phe-His-Sta-Ile-NH2 | CHEMBL419531)
Affinity DataIC50:  0.100nMAssay Description:In vitro inhibitory activity against human plasma reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Upjohn

Curated by ChEMBL
LigandPNGBDBM50368278(CHEMBL1790497)
Affinity DataIC50:  0.110nMAssay Description:In vitro inhibitory activity against human plasma reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Rattus norvegicus)
Upjohn

Curated by ChEMBL
LigandPNGBDBM50014102(Boc-Pro-Phe-N(Me) His-Leu[CHOHCH2]Val-Ile-THAM Ami...)
Affinity DataIC50:  0.260nMAssay Description:Tested invitro for inhibitory activity against plasma renin in rat modelsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Rattus norvegicus)
Upjohn

Curated by ChEMBL
LigandPNGBDBM50014100(2-(1-{[1-{2-Hydroxy-1-isobutyl-5-methyl-4-[2-methy...)
Affinity DataIC50:  0.260nMAssay Description:Tested invitro for inhibitory activity against plasma renin in rat modelsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Upjohn

Curated by ChEMBL
LigandPNGBDBM50011341(2-Amino-5-[2-(1-{[1-[1-cyclohexylmethyl-2-hydroxy-...)
Affinity DataIC50:  0.280nMAssay Description:Inhibition of human plasma renin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Upjohn

Curated by ChEMBL
LigandPNGBDBM50011339(2-Amino-5-[2-(1-{[1-(1-cyclohexylmethyl-2-hydroxy-...)
Affinity DataIC50:  0.290nMAssay Description:Inhibition of human plasma renin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Upjohn

Curated by ChEMBL
LigandPNGBDBM50011347(5-[2-{[2-(3-Amino-3-methyl-butyrylamino)-3-phenyl-...)
Affinity DataIC50:  0.290nMAssay Description:Inhibition of human plasma renin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Upjohn

Curated by ChEMBL
LigandPNGBDBM50406474(CHEMBL2028945)
Affinity DataIC50:  0.310nMAssay Description:Inhibition of human plasma renin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Upjohn

Curated by ChEMBL
LigandPNGBDBM50022861(Ac-Ftr-Pro-Phe-His-Leu(psi)[CH(OH)CH2]Val-NH2 | CH...)
Affinity DataIC50:  0.310nMAssay Description:In vitro inhibitory activity against human plasma reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Upjohn

Curated by ChEMBL
LigandPNGBDBM50011342(2-Amino-5-[2-(1-{[1-(1-cyclohexylmethyl-2-hydroxy-...)
Affinity DataIC50:  0.320nMAssay Description:Inhibition of human plasma renin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Rattus norvegicus)
Upjohn

Curated by ChEMBL
LigandPNGBDBM50014105(2-(1-{[1-{2-Hydroxy-1-isobutyl-5-methyl-4-[2-methy...)
Affinity DataIC50:  0.330nMAssay Description:Tested invitro for inhibitory activity against plasma renin in rat modelsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Rattus norvegicus)
Upjohn

Curated by ChEMBL
LigandPNGBDBM50014106(CHEMBL429882 | N-[[[2-Hydroxy-1,1-bis(hydroxymethy...)
Affinity DataIC50:  0.330nMAssay Description:Tested invitro for inhibitory activity against plasma renin in rat modelsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Upjohn

Curated by ChEMBL
LigandPNGBDBM50368112(CHEMBL1790062)
Affinity DataIC50:  0.340nMpH: 6.0Assay Description:Inhibition of human plasma renin at pH 6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Upjohn

Curated by ChEMBL
LigandPNGBDBM50022846(Ac-Ftr-Pro-Phe-His-Sta-Val-Ftr-NH2 | CHEMBL275711)
Affinity DataIC50:  0.380nMAssay Description:In vitro inhibitory activity against human plasma reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Upjohn

Curated by ChEMBL
LigandPNGBDBM50011337(5-[2-{[2-(3-Amino-3-methyl-butyrylamino)-3-phenyl-...)
Affinity DataIC50:  0.410nMAssay Description:Inhibition of human plasma renin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Upjohn

Curated by ChEMBL
LigandPNGBDBM50011348(5-[2-{[2-(3-Amino-3-methyl-butyrylamino)-3-phenyl-...)
Affinity DataIC50:  0.430nMAssay Description:Inhibition of human plasma renin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Upjohn

Curated by ChEMBL
LigandPNGBDBM50011345(CHEMBL3143483 | Phosphoric acid mono-{4-[2-(1-{[1-...)
Affinity DataIC50:  0.450nMAssay Description:Inhibition of human plasma renin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Rattus norvegicus)
Upjohn

Curated by ChEMBL
LigandPNGBDBM50014099(CHEMBL414795 | N-[(D-Glucosylamino)carbonyl]-Pro-P...)
Affinity DataIC50:  0.490nMAssay Description:Tested invitro for inhibitory activity against plasma renin in rat modelsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Upjohn

Curated by ChEMBL
LigandPNGBDBM50025927(CHEMBL3143966 | {1-[1-[1-(2,2-Difluoro-2-{2-methyl...)
Affinity DataIC50:  0.520nMAssay Description:Plasma renin inhibitory activity was evaluated in lyophilized human plasma with 0.1%EDTAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Upjohn

Curated by ChEMBL
LigandPNGBDBM50024146(CHEMBL3142169 | {1-[1-[1-(2,2-Difluoro-2-{2-methyl...)
Affinity DataIC50:  0.520nMAssay Description:Inhibition of human plasma reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Upjohn

Curated by ChEMBL
LigandPNGBDBM50022845(Ac-Ftr-Pro-Phe-His-Sta-Val-NH2 | CHEMBL318388)
Affinity DataIC50:  0.530nMAssay Description:In vitro inhibitory activity against human plasma reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Upjohn

Curated by ChEMBL
LigandPNGBDBM50024149(CHEMBL3142178 | {1-[1-(1-Cyclohexylmethyl-3,3-difl...)
Affinity DataIC50:  0.570nMAssay Description:Inhibition of human plasma reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Rattus norvegicus)
Upjohn

Curated by ChEMBL
LigandPNGBDBM50014104(CHEMBL410067 | N-[[[2-Hydroxy-1,1-bis(hydroxymethy...)
Affinity DataIC50:  0.580nMAssay Description:Tested invitro for inhibitory activity against plasma renin in rat modelsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Upjohn

Curated by ChEMBL
LigandPNGBDBM50024156(2-(1-{[1-(2-Hydroxy-1-isobutyl-5-methyl-4-{2-methy...)
Affinity DataIC50:  0.650nMAssay Description:Inhibition of human plasma reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Upjohn

Curated by ChEMBL
LigandPNGBDBM50024151((1-{[1-(2-Hydroxy-1-isobutyl-5-methyl-4-{2-methyl-...)
Affinity DataIC50:  0.650nMAssay Description:Inhibition of human plasma reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Upjohn

Curated by ChEMBL
LigandPNGBDBM50011343(CHEMBL3143477 | Sodium; 2-{[7-(1-{[1-(2-hydroxy-1-...)
Affinity DataIC50:  0.660nMAssay Description:Inhibition of human plasma renin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Upjohn

Curated by ChEMBL
LigandPNGBDBM50368109(CHEMBL1790066)
Affinity DataIC50:  0.700nMpH: 6.0Assay Description:Inhibition of human plasma renin at pH 6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Upjohn

Curated by ChEMBL
LigandPNGBDBM50022836(CGP-2928 | CHEMBL216847 | Z-Arg-Arg-Pro-Phe-His-St...)
Affinity DataIC50:  1nMAssay Description:In vitro inhibitory activity against human plasma reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Rattus norvegicus)
Upjohn

Curated by ChEMBL
LigandPNGBDBM50014101(CHEMBL265833 | N-[4,5-Dihydro-4,4-bis(hydroxymethy...)
Affinity DataIC50:  1.10nMAssay Description:Tested invitro for inhibitory activity against plasma renin in rat modelsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Rattus norvegicus)
Upjohn

Curated by ChEMBL
LigandPNGBDBM50014103(CHEMBL263257 | N-[(D-Glucosylamino)carbonyl]-Pro-P...)
Affinity DataIC50:  1.10nMAssay Description:Tested invitro for inhibitory activity against plasma renin in rat modelsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Upjohn

Curated by ChEMBL
LigandPNGBDBM50011346(CHEMBL3143482 | Sodium; 2-{[7-(1-{[1-(2-hydroxy-1-...)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of human plasma renin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Upjohn

Curated by ChEMBL
LigandPNGBDBM50368104(CHEMBL1790067)
Affinity DataIC50:  1.20nMpH: 6.0Assay Description:Inhibition of human plasma renin at pH 6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Upjohn

Curated by ChEMBL
LigandPNGBDBM50024144(CHEMBL3142193 | {1-[1-(1-Benzyl-3,3-difluoro-3-{2-...)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of human plasma reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Upjohn

Curated by ChEMBL
LigandPNGBDBM50024145(CHEMBL3350345 | {1-[1-(1-Cyclohexylmethyl-3,3-difl...)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of human plasma reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Upjohn

Curated by ChEMBL
LigandPNGBDBM50022844(Ac-Trp-Pro-Phe-His-Sta-Ile-NH2 | CHEMBL317280)
Affinity DataIC50:  1.60nMAssay Description:In vitro inhibitory activity against human plasma reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Upjohn

Curated by ChEMBL
LigandPNGBDBM50011350(CHEMBL3143484 | Phosphoric acid mono-{2-[2-(1-{[1-...)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of human plasma renin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Upjohn

Curated by ChEMBL
LigandPNGBDBM50024214(Boc-alpha-MePro-Phe-His-Leu si[CHOHCH2]Val-Ile-Amp...)
Affinity DataIC50:  1.60nMAssay Description:In vitro inhibition against human plasma renin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Upjohn

Curated by ChEMBL
LigandPNGBDBM50025928(CHEMBL57121 | {1-[1-[1-(1-Hydroxy-2-{2-methyl-1-[(...)
Affinity DataIC50:  1.70nMAssay Description:Plasma renin inhibitory activity was evaluated in lyophilized human plasma with 0.1%EDTAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Upjohn

Curated by ChEMBL
LigandPNGBDBM50023078(1N-[2-methyl-1-(2-pyridylmethylcarbamoyl)butyl]-4-...)
Affinity DataIC50:  1.70nMAssay Description:Inhibitory activity against human plasma renin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Upjohn

Curated by ChEMBL
LigandPNGBDBM50024147(CHEMBL3142170 | {1-[1-[1-(1-Hydroxy-2-{2-methyl-1-...)
Affinity DataIC50:  1.70nMAssay Description:Inhibition of human plasma reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Upjohn

Curated by ChEMBL
LigandPNGBDBM50406476(CHEMBL2028948)
Affinity DataIC50:  1.80nMAssay Description:Inhibition of human plasma renin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Upjohn

Curated by ChEMBL
LigandPNGBDBM50368105(CHEMBL1790064)
Affinity DataIC50:  1.90nMpH: 6.0Assay Description:Inhibition of human plasma renin at pH 6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Upjohn

Curated by ChEMBL
LigandPNGBDBM50406473(CHEMBL2028947)
Affinity DataIC50:  1.90nMAssay Description:Inhibition of human plasma renin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Upjohn

Curated by ChEMBL
LigandPNGBDBM50367481(CHEMBL1237141 | CHEMBL3143428)
Affinity DataIC50:  2nMAssay Description:In vitro inhibition against hog renin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Upjohn

Curated by ChEMBL
LigandPNGBDBM50368107(CHEMBL1790070)
Affinity DataIC50:  2nMpH: 6.0Assay Description:Inhibition of human plasma renin at pH 6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Upjohn

Curated by ChEMBL
LigandPNGBDBM50406365(CHEMBL2021411)
Affinity DataIC50:  2.20nMpH: 6.0Assay Description:Inhibition of human plasma renin at pH 6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Upjohn

Curated by ChEMBL
LigandPNGBDBM50024143(CHEMBL3142184 | {1-[1-[1-(2,2-Difluoro-2-{2-methyl...)
Affinity DataIC50:  2.5nMAssay Description:Inhibition of human plasma reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Upjohn

Curated by ChEMBL
LigandPNGBDBM50406475(CHEMBL2028946)
Affinity DataIC50:  2.5nMAssay Description:Inhibition of human plasma renin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Upjohn

Curated by ChEMBL
LigandPNGBDBM50024212(2-{1-[1-[1-(1-Hydroxy-2-{2-methyl-1-[(pyridin-2-yl...)
Affinity DataIC50:  3.5nMAssay Description:In vitro inhibition against human plasma renin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Upjohn

Curated by ChEMBL
LigandPNGBDBM50368110(CHEMBL1790076)
Affinity DataIC50:  3.5nMpH: 6.0Assay Description:Inhibition of human plasma renin at pH 6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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