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Found 244 with Last Name = 'rascon' and Initial = 'j'
TargetTyrosine-protein phosphatase non-receptor type 7(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM88776(2-[4-[(Z)-[5-(4-chlorophenyl)-6-isopropoxycarbonyl...)
Affinity DataKi:  690nMAssay Description:Competitive inhibition of recombinant HePTP expressed in Escherichia coli by Michaelis-Menten kinetic analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntestinal-type alkaline phosphatase(Mus musculus)
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50447413(CHEMBL3115157)
Affinity DataKi:  3.20E+3nMAssay Description:Competitive inhibition of mouse duodenal-specific FLAG-tagged IAP expressed in African green monkey COS1 cells using p-nitrophenyl phosphate as subst...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntestinal-type alkaline phosphatase(Mus musculus)
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM76214(CHEMBL1322977 | MLS001096094 | N-(2,5-dimethylphen...)
Affinity DataIC50:  400nMAssay Description:Inhibition of mouse duodenal-specific FLAG-tagged IAP expressed in African green monkey COS1 cells after 30 mins by chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntestinal-type alkaline phosphatase(Mus musculus)
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50447450(CHEMBL3115119)
Affinity DataIC50:  530nMAssay Description:Inhibition of mouse duodenal-specific FLAG-tagged IAP expressed in African green monkey COS1 cells after 30 mins by chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntestinal-type alkaline phosphatase(Mus musculus)
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50447413(CHEMBL3115157)
Affinity DataIC50:  540nMAssay Description:Inhibition of mouse duodenal-specific FLAG-tagged IAP expressed in African green monkey COS1 cells after 30 mins by chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntestinal-type alkaline phosphatase(Mus musculus)
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50447458(CHEMBL3115158)
Affinity DataIC50:  730nMAssay Description:Inhibition of mouse duodenal-specific FLAG-tagged IAP expressed in African green monkey COS1 cells after 30 mins by chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 7(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM88776(2-[4-[(Z)-[5-(4-chlorophenyl)-6-isopropoxycarbonyl...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of recombinant HePTP expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMannose-6-phosphate isomerase(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM44461(5-[(2-methoxyphenyl)-oxomethoxy]-1-phenyl-3-pyrazo...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of human purified phosphomannose isomeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMannose-6-phosphate isomerase(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM44446(4-[2-[[(5Z)-5-(3-indolylidene)-4-(2-methoxyethyl)-...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of human purified phosphomannose isomeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 7(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50378898(CHEMBL1672292)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of recombinant HePTP expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMannose-6-phosphate isomerase(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM44443(2-[1,3-bis(oxidanylidene)isoindol-2-yl]-N-[3-cyano...)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of human purified phosphomannose isomeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntestinal-type alkaline phosphatase(Mus musculus)
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50447426(CHEMBL3115137)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of mouse duodenal-specific FLAG-tagged IAP expressed in African green monkey COS1 cells after 30 mins by chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntestinal-type alkaline phosphatase(Mus musculus)
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50447415(CHEMBL3115148)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of mouse duodenal-specific FLAG-tagged IAP expressed in African green monkey COS1 cells after 30 mins by chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 7(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50378899(CHEMBL1672293)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of recombinant HePTP expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMannose-6-phosphate isomerase(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM46732(2-(4-chlorophenyl)-5-fluoranyl-1,2-benzothiazol-3-...)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of human purified phosphomannose isomeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntestinal-type alkaline phosphatase(Mus musculus)
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM76215(CHEMBL1349252 | MLS001096095 | N-(3-cyanophenyl)-3...)
Affinity DataIC50:  1.82E+3nMAssay Description:Inhibition of mouse duodenal-specific FLAG-tagged IAP expressed in African green monkey COS1 cells after 30 mins by chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMannose-6-phosphate isomerase(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM44457((4Z)-4-[(2-methylsulfanylanilino)methylidene]-2-ph...)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of human purified phosphomannose isomeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMannose-6-phosphate isomerase(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM44445(3-(1,3-benzodioxol-5-ylmethyl)-7-(piperidin-1-ylca...)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of human purified phosphomannose isomeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMannose-6-phosphate isomerase(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM46691(2-(4-chlorophenyl)-1,2-benzothiazol-3-one | MLS-03...)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of human purified phosphomannose isomeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntestinal-type alkaline phosphatase(Mus musculus)
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50447449(CHEMBL3115120)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of mouse duodenal-specific FLAG-tagged IAP expressed in African green monkey COS1 cells after 30 mins by chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntestinal-type alkaline phosphatase(Mus musculus)
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50447425(CHEMBL3115138)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of mouse duodenal-specific FLAG-tagged IAP expressed in African green monkey COS1 cells after 30 mins by chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntestinal-type alkaline phosphatase(Mus musculus)
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50447457(CHEMBL3115159)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of mouse duodenal-specific FLAG-tagged IAP expressed in African green monkey COS1 cells after 30 mins by chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntestinal-type alkaline phosphatase(Mus musculus)
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50447448(CHEMBL3115121)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibition of mouse duodenal-specific FLAG-tagged IAP expressed in African green monkey COS1 cells after 30 mins by chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntestinal-type alkaline phosphatase(Mus musculus)
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50447447(CHEMBL3115122)
Affinity DataIC50:  2.60E+3nMAssay Description:Inhibition of mouse duodenal-specific FLAG-tagged IAP expressed in African green monkey COS1 cells after 30 mins by chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMannose-6-phosphate isomerase(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM34849(6-fluoranyl-2-(2-methylphenyl)-1,2-benzothiazol-3-...)
Affinity DataIC50:  2.90E+3nMAssay Description:Inhibition of human purified phosphomannose isomeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMannose-6-phosphate isomerase(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM44382(3-(2-Chloro-phenyl)-7-methyl-7H-pyrazolo[4,3-e][1,...)
Affinity DataIC50:  3.10E+3nMAssay Description:Inhibition of human purified phosphomannose isomeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMannose-6-phosphate isomerase(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM44453(MLS000102133 | N-[(1,2-dimethyl-5-indolyl)methyl]-...)
Affinity DataIC50:  3.40E+3nMAssay Description:Inhibition of human purified phosphomannose isomeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMannose-6-phosphate isomerase(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM44460(1-Amino-4-bromo-anthraquinone | 1-amino-4-bromo-9,...)
Affinity DataIC50:  3.60E+3nMAssay Description:Inhibition of human purified phosphomannose isomeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMannose-6-phosphate isomerase(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM46694(2-(3-methoxyphenyl)-1,2-benzothiazol-3-one | MLS-0...)
Affinity DataIC50:  3.70E+3nMAssay Description:Inhibition of human purified phosphomannose isomeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 7(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50336847(2-(4-((5-(2-chlorophenyl)-6-(ethoxycarbonyl)-7-met...)
Affinity DataIC50:  3.70E+3nMAssay Description:Inhibition of recombinant HePTP expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntestinal-type alkaline phosphatase(Mus musculus)
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50447413(CHEMBL3115157)
Affinity DataIC50:  3.80E+3nMAssay Description:Inhibition of mouse duodenal-specific FLAG-tagged IAP expressed in African green monkey COS1 cells using p-nitrophenyl phosphate as substrate after 3...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein phosphatase 3(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50378898(CHEMBL1672292)
Affinity DataIC50:  4.20E+3nMAssay Description:Inhibition of recombinant VHR expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntestinal-type alkaline phosphatase(Mus musculus)
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50447424(CHEMBL3115139)
Affinity DataIC50:  4.20E+3nMAssay Description:Inhibition of mouse duodenal-specific FLAG-tagged IAP expressed in African green monkey COS1 cells after 30 mins by chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMannose-6-phosphate isomerase(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM46692(2-(3-iodanylphenyl)-1,2-benzothiazol-3-one | 2-(3-...)
Affinity DataIC50:  4.30E+3nMAssay Description:Inhibition of human purified phosphomannose isomeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMannose-6-phosphate isomerase(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM46731(5-fluoranyl-2-(2-fluorophenyl)-1,2-benzothiazol-3-...)
Affinity DataIC50:  4.30E+3nMAssay Description:Inhibition of human purified phosphomannose isomeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 7(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50336848(2-(4-((6-(ethoxycarbonyl)-5-(3-methoxyphenyl)-7-me...)
Affinity DataIC50:  4.60E+3nMAssay Description:Inhibition of recombinant HePTP expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntestinal-type alkaline phosphatase(Mus musculus)
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50447456(CHEMBL3115160)
Affinity DataIC50:  4.70E+3nMAssay Description:Inhibition of mouse duodenal-specific FLAG-tagged IAP expressed in African green monkey COS1 cells after 30 mins by chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMannose-6-phosphate isomerase(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM44454(2-(2-furanylmethylidene)-5-(3-methoxyphenyl)-7-met...)
Affinity DataIC50:  4.80E+3nMAssay Description:Inhibition of human purified phosphomannose isomeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMannose-6-phosphate isomerase(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM44441(MLS000098295 | SMR000066971 | cid_2998095)
Affinity DataIC50:  4.90E+3nMAssay Description:Inhibition of human purified phosphomannose isomeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMannose-6-phosphate isomerase(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM44458(4-[[benzenesulfonyl(2-pyridinyl)amino]methyl]benzo...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of human purified phosphomannose isomeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMannose-6-phosphate isomerase(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM34737(2-(4-methylphenyl)-1,2-benzisothiazol-3(2H)-one | ...)
Affinity DataIC50:  5.20E+3nMAssay Description:Inhibition of human purified phosphomannose isomeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMannose-6-phosphate isomerase(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM44450((3,5-dimethylpyrazol-1-yl)methyl-[4-(trifluorometh...)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibition of human purified phosphomannose isomeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntestinal-type alkaline phosphatase(Mus musculus)
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50447422(CHEMBL3115141)
Affinity DataIC50:  6.30E+3nMAssay Description:Inhibition of mouse duodenal-specific FLAG-tagged IAP expressed in African green monkey COS1 cells after 30 mins by chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMannose-6-phosphate isomerase(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM44439(2-(3-pyrrolidin-1-ylquinoxalin-2-yl)-2-thiophen-2-...)
Affinity DataIC50:  6.40E+3nMAssay Description:Inhibition of human purified phosphomannose isomeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein phosphatase 3(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50336847(2-(4-((5-(2-chlorophenyl)-6-(ethoxycarbonyl)-7-met...)
Affinity DataIC50:  6.50E+3nMAssay Description:Inhibition of recombinant VHR expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMannose-6-phosphate isomerase(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM44440(2-[[4-methyl-5-(2-methyl-3-furanyl)-1,2,4-triazol-...)
Affinity DataIC50:  6.60E+3nMAssay Description:Inhibition of human purified phosphomannose isomeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMannose-6-phosphate isomerase(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM44438(2-methyl-3-(4-methylphenyl)[1]benzopyrano[2,3-d]py...)
Affinity DataIC50:  7.20E+3nMAssay Description:Inhibition of human purified phosphomannose isomeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphomannomutase 2(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM44446(4-[2-[[(5Z)-5-(3-indolylidene)-4-(2-methoxyethyl)-...)
Affinity DataIC50:  7.30E+3nMAssay Description:Inhibition of human purified PMM2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntestinal-type alkaline phosphatase(Mus musculus)
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50447423(CHEMBL3115140)
Affinity DataIC50:  7.40E+3nMAssay Description:Inhibition of mouse duodenal-specific FLAG-tagged IAP expressed in African green monkey COS1 cells after 30 mins by chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntestinal-type alkaline phosphatase(Mus musculus)
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50447446(CHEMBL3115123)
Affinity DataIC50:  7.70E+3nMAssay Description:Inhibition of mouse duodenal-specific FLAG-tagged IAP expressed in African green monkey COS1 cells after 30 mins by chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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