Compile Data Set for Download or QSAR
maximum 50k data
Found 2323 with Last Name = 'sacchi' and Initial = 'a'
TargetAdenosine receptor A3(Homo sapiens (Human))
Universit?? Di Napoli Federico Ii

LigandPNGBDBM198126((2S,3S,4R,5R)-5-[2-chloro-6-[(3-iodophenyl)methyla...)
Affinity DataKi:  0.220nM ΔG°:  -55.1kJ/molepH: 7.4 T: 2°CAssay Description:Aliquots of cell membranes (90 ug) were incubated at 25 °C for 180 min in 500 uL of binding buffer (50 mM Tris-HCl, 5 mM MgCl2, 1 mM EDTA, 2 un...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
Universit?? Di Napoli Federico Ii

LigandPNGBDBM21173(1,3-dipropyl-8-cyclopentylxanthine | 8-cyclopentyl...)
Affinity DataKi:  0.5nM ΔG°:  -53.1kJ/molepH: 7.4 T: 2°CAssay Description:Aliquots of cell membranes (30 ug proteins) were incubated at 25 °C for 180 min in 500 uL of binding buffer (50 mM Tris-HCl, 2 mM MgCl2, 2 units/...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50048364(CHEMBL3309997)
Affinity DataKi:  1nMAssay Description:Inhibition of Hsp90 (unknown origin) by FP displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Irccs Ospedale San Raffaele

Curated by ChEMBL
LigandPNGBDBM50235980(2-((2S,5R,8S,11S)-5-benzyl-11-(3-guanidinopropyl)-...)
Affinity DataKi:  1nMAssay Description:Binding affinity to human integrin alphaVbeta3 receptor using acetyl-CisoDGRCGVRSSSRTPSDKY-bio probe and streptavidin-peroxidase conjugate incubated ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50048357(CHEMBL3309990)
Affinity DataKi:  5nMAssay Description:Inhibition of Hsp90 (unknown origin) by FP displacement assayMore data for this Ligand-Target Pair
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM158154(US10081622, Compound 11 | US10370379, Entrectinib ...)
Affinity DataKi:  6.20nMAssay Description:Inhibition of recombinant ALK (unknown origin)More data for this Ligand-Target Pair
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Irccs Ospedale San Raffaele

Curated by ChEMBL
LigandPNGBDBM50340641(CHEMBL4161189)
Affinity DataKi:  6.30nMAssay Description:Binding affinity to human integrin alphaVbeta3 receptor using acetyl-CisoDGRCGVRSSSRTPSDKY-bio probe and streptavidin-peroxidase conjugate incubated ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50048374(CHEMBL3310151)
Affinity DataKi:  9nMAssay Description:Inhibition of Hsp90 (unknown origin) by FP displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50048365(CHEMBL3309998)
Affinity DataKi:  12nMAssay Description:Inhibition of Hsp90 (unknown origin) by FP displacement assayMore data for this Ligand-Target Pair
TargetAdenosine receptor A1(Homo sapiens (Human))
Universit?? Di Napoli Federico Ii

LigandPNGBDBM86761(CAS_35920-39-9 | NECA | NSC_448222)
Affinity DataKi:  14nM ΔG°:  -44.8kJ/molepH: 7.4 T: 2°CAssay Description:Aliquots of cell membranes (30 ug proteins) were incubated at 25 °C for 180 min in 500 uL of binding buffer (50 mM Tris-HCl, 2 mM MgCl2, 2 units/...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Universit?? Di Napoli Federico Ii

LigandPNGBDBM86761(CAS_35920-39-9 | NECA | NSC_448222)
Affinity DataKi:  16nM ΔG°:  -44.5kJ/molepH: 7.4 T: 2°CAssay Description:Aliquots of cell membranes (30 ug) were incubated at 25 °C for 90 min in 500 uL of binding buffer (50 mM Tris-HCl, 2 mm MgCl2, 2 units/mL ADA, ...More data for this Ligand-Target Pair
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Irccs Ospedale San Raffaele

Curated by ChEMBL
LigandPNGBDBM50340638(CHEMBL4168458)
Affinity DataKi:  20nMAssay Description:Binding affinity to human integrin alphaVbeta3 receptor using acetyl-CisoDGRCGVRSSSRTPSDKY-bio probe and streptavidin-peroxidase conjugate incubated ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Irccs Ospedale San Raffaele

Curated by ChEMBL
LigandPNGBDBM50340643(CHEMBL4165038)
Affinity DataKi:  22nMAssay Description:Binding affinity to human integrin alphaVbeta3 receptor using acetyl-CisoDGRCGVRSSSRTPSDKY-bio probe and streptavidin-peroxidase conjugate incubated ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Irccs Ospedale San Raffaele

Curated by ChEMBL
LigandPNGBDBM50340640(CHEMBL4160559)
Affinity DataKi:  27nMAssay Description:Binding affinity to human integrin alphaVbeta3 receptor using acetyl-CisoDGRCGVRSSSRTPSDKY-bio probe and streptavidin-peroxidase conjugate incubated ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50048367(CHEMBL3310000)
Affinity DataKi:  30nMAssay Description:Inhibition of Hsp90 (unknown origin) by FP displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50048372(CHEMBL3309269)
Affinity DataKi:  34nMAssay Description:Inhibition of Hsp90 (unknown origin) by FP displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50048354(CHEMBL3309985)
Affinity DataKi:  35nMAssay Description:Inhibition of Hsp90 (unknown origin) by FP displacement assayMore data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50048369(CHEMBL3310002)
Affinity DataKi:  45nMAssay Description:Inhibition of Hsp90 (unknown origin) by FP displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50048371(CHEMBL3310004)
Affinity DataKi:  56nMAssay Description:Inhibition of Hsp90 (unknown origin) by FP displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50048370(CHEMBL3310003)
Affinity DataKi:  64nMAssay Description:Inhibition of Hsp90 (unknown origin) by FP displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Universit?? Di Napoli Federico Ii

LigandPNGBDBM86761(CAS_35920-39-9 | NECA | NSC_448222)
Affinity DataKi:  73nM ΔG°:  -40.7kJ/molepH: 7.4 T: 2°CAssay Description:Aliquots of cell membranes (90 ug) were incubated at 25 °C for 180 min in 500 uL of binding buffer (50 mM Tris-HCl, 5 mM MgCl2, 1 mM EDTA, 2 un...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50048358(CHEMBL3309991)
Affinity DataKi:  79nMAssay Description:Inhibition of Hsp90 (unknown origin) by FP displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50048362(CHEMBL3309995)
Affinity DataKi:  81nMAssay Description:Inhibition of Hsp90 (unknown origin) by FP displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50048368(CHEMBL3310001)
Affinity DataKi:  84nMAssay Description:Inhibition of Hsp90 (unknown origin) by FP displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50048366(CHEMBL3309999)
Affinity DataKi:  87nMAssay Description:Inhibition of Hsp90 (unknown origin) by FP displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50048356(CHEMBL3309989)
Affinity DataKi:  88nMAssay Description:Inhibition of Hsp90 (unknown origin) by FP displacement assayMore data for this Ligand-Target Pair
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Irccs Ospedale San Raffaele

Curated by ChEMBL
LigandPNGBDBM50340639(CHEMBL4171425)
Affinity DataKi:  103nMAssay Description:Binding affinity to human integrin alphaVbeta3 receptor using acetyl-CisoDGRCGVRSSSRTPSDKY-bio probe and streptavidin-peroxidase conjugate incubated ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50048360(CHEMBL3309993)
Affinity DataKi:  126nMAssay Description:Inhibition of Hsp90 (unknown origin) by FP displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 5(Homo sapiens (Human))
Harvard Medical School

LigandPNGBDBM50155426(1,3,5,8-Tetrahydroxy-xanthen-9-one | 1,3,5,8-tetra...)
Affinity DataKi:  140nMAssay Description:Cdk5, 33P-ATP and cofactors were added in the presence of tau protein. The reaction mixture was incubated to allow Cdk5 to transfer 33P from ATP to ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50048354(CHEMBL3309985)
Affinity DataKi:  170nMAssay Description:Inhibition of Hsp90 (unknown origin) by NMR FAXS screening methodMore data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50048375(CHEMBL3310152)
Affinity DataKi:  179nMAssay Description:Inhibition of Hsp90 (unknown origin) by FP displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 5(Homo sapiens (Human))
Harvard Medical School

LigandPNGBDBM50155426(1,3,5,8-Tetrahydroxy-xanthen-9-one | 1,3,5,8-tetra...)
Affinity DataKi:  200nM IC50:  200nMAssay Description:Cdk5, 33P-ATP and cofactors were added in the presence of tau protein. The reaction mixture was incubated to allow Cdk5 to transfer 33P from ATP to ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50048379(CHEMBL3310156)
Affinity DataKi:  257nMAssay Description:Inhibition of Hsp90 (unknown origin) by FP displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50048361(CHEMBL3309994)
Affinity DataKi:  332nMAssay Description:Inhibition of Hsp90 (unknown origin) by FP displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Universit?? Di Napoli Federico Ii

LigandPNGBDBM21173(1,3-dipropyl-8-cyclopentylxanthine | 8-cyclopentyl...)
Affinity DataKi:  337nM ΔG°:  -36.9kJ/molepH: 7.4 T: 2°CAssay Description:Aliquots of cell membranes (30 ug) were incubated at 25 °C for 90 min in 500 uL of binding buffer (50 mM Tris-HCl, 2 mm MgCl2, 2 units/mL ADA, ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Universit?? Di Napoli Federico Ii

LigandPNGBDBM198126((2S,3S,4R,5R)-5-[2-chloro-6-[(3-iodophenyl)methyla...)
Affinity DataKi:  401nM ΔG°:  -36.5kJ/molepH: 7.4 T: 2°CAssay Description:Aliquots of cell membranes (30 ug) were incubated at 25 °C for 90 min in 500 uL of binding buffer (50 mM Tris-HCl, 2 mm MgCl2, 2 units/mL ADA, ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50048378(CHEMBL3310155)
Affinity DataKi:  656nMAssay Description:Inhibition of Hsp90 (unknown origin) by FP displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 5(Homo sapiens (Human))
Harvard Medical School

LigandPNGBDBM59194(4-aminothiazole, 2.0)
Affinity DataKi:  660nM IC50:  2.00E+3nMAssay Description:Cdk5, 33P-ATP and cofactors were added in the presence of tau protein. The reaction mixture was incubated to allow Cdk5 to transfer 33P from ATP to ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 5(Homo sapiens (Human))
Harvard Medical School

LigandPNGBDBM59194(4-aminothiazole, 2.0)
Affinity DataKi:  690nMAssay Description:Cdk5, 33P-ATP and cofactors were added in the presence of tau protein. The reaction mixture was incubated to allow Cdk5 to transfer 33P from ATP to ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50048355(CHEMBL3309988)
Affinity DataKi:  690nMAssay Description:Inhibition of Hsp90 (unknown origin) by FP displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
Universit?? Di Napoli Federico Ii

LigandPNGBDBM198126((2S,3S,4R,5R)-5-[2-chloro-6-[(3-iodophenyl)methyla...)
Affinity DataKi:  890nM ΔG°:  -34.5kJ/molepH: 7.4 T: 2°CAssay Description:Aliquots of cell membranes (30 ug proteins) were incubated at 25 °C for 180 min in 500 uL of binding buffer (50 mM Tris-HCl, 2 mM MgCl2, 2 units/...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
Universit?? Di Napoli Federico Ii

LigandPNGBDBM198129(4-amino-6-alkyloxy-2-benzylthiopyrimidines (6))
Affinity DataKi:  1.20E+3nM ΔG°:  -33.8kJ/molepH: 7.4 T: 2°CAssay Description:Aliquots of cell membranes (30 ug proteins) were incubated at 25 °C for 180 min in 500 uL of binding buffer (50 mM Tris-HCl, 2 mM MgCl2, 2 units/...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
Universit?? Di Napoli Federico Ii

LigandPNGBDBM198127(4-amino-6-alkyloxy-2-benzylthiopyrimidines (4))
Affinity DataKi:  1.24E+3nM ΔG°:  -33.7kJ/molepH: 7.4 T: 2°CAssay Description:Aliquots of cell membranes (30 ug proteins) were incubated at 25 °C for 180 min in 500 uL of binding buffer (50 mM Tris-HCl, 2 mM MgCl2, 2 units/...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
Universit?? Di Napoli Federico Ii

LigandPNGBDBM198128(4-amino-6-alkyloxy-2-benzylthiopyrimidines (5))
Affinity DataKi:  1.95E+3nM ΔG°:  -32.6kJ/molepH: 7.4 T: 2°CAssay Description:Aliquots of cell membranes (30 ug proteins) were incubated at 25 °C for 180 min in 500 uL of binding buffer (50 mM Tris-HCl, 2 mM MgCl2, 2 units/...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50048390(CHEMBL3309983)
Affinity DataKi:  2.10E+3nMAssay Description:Inhibition of Hsp90 (unknown origin) by NMR FAXS screening methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50048391(CHEMBL3309984)
Affinity DataKi:  2.40E+3nMAssay Description:Inhibition of Hsp90 (unknown origin) by NMR FAXS screening methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50048387(CHEMBL3309981)
Affinity DataKi:  2.60E+3nMAssay Description:Inhibition of Hsp90 (unknown origin) by NMR FAXS screening methodMore data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50048388(CHEMBL3309982)
Affinity DataKi:  3.10E+3nMAssay Description:Inhibition of Hsp90 (unknown origin) by NMR FAXS screening methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50048385(CHEMBL3309980)
Affinity DataKi:  3.50E+3nMAssay Description:Inhibition of Hsp90 (unknown origin) by NMR FAXS screening methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50048376(CHEMBL3310153)
Affinity DataKi: >5.00E+3nMAssay Description:Inhibition of Hsp90 (unknown origin) by FP displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 2323 total ) | Next | Last >>
Jump to: