Affinity DataKi: 2.40nMAssay Description:Binding affinity to human NK2 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 2.40nMAssay Description:Binding affinity to human NK3 receptorMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataKi: 44nMAssay Description:Displacement of radiolabeled MK-499 from human ERG channelMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataKi: 50nMAssay Description:Inhibition of MK499 binding to human ERGMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataKi: 80nMAssay Description:Inhibition of MK499 binding to human ERGMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataKi: 290nMAssay Description:Inhibition of MK499 binding to human ERGMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataKi: 300nMAssay Description:Displacement of radiolabeled MK-499 from human ERG channelMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataKi: 369nMAssay Description:Displacement of radiolabeled MK-499 from human ERG channelMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataKi: 377nMAssay Description:Displacement of radiolabeled MK-499 from human ERG channelMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataKi: 385nMAssay Description:Displacement of radiolabeled MK-499 from human ERG channelMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataKi: 440nMAssay Description:Inhibition of MK499 binding to human ERGMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataKi: 462nMAssay Description:Displacement of radiolabeled MK-499 from human ERG channelMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataKi: 543nMAssay Description:Displacement of radiolabeled MK-499 from human ERG channelMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataKi: 720nMAssay Description:Inhibition of MK499 binding to human ERGMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataKi: 1.40E+3nMAssay Description:Displacement of radiolabeled MK-499 from human ERG channelMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataKi: 1.64E+3nMAssay Description:Displacement of radiolabeled MK-499 from human ERG channelMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataKi: 1.70E+3nMAssay Description:Displacement of radiolabeled MK-499 from human ERG channelMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataKi: 2.19E+3nMAssay Description:Displacement of radiolabeled MK-499 from human ERG channelMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataKi: 2.21E+3nMAssay Description:Displacement of radiolabeled MK-499 from human ERG channelMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataKi: 2.62E+3nMAssay Description:Displacement of radiolabeled MK-499 from human ERG channelMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataKi: 2.87E+3nMAssay Description:Inhibition of MK499 binding to human ERGMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0600nMAssay Description:Displacement of [125I]substance P from human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0600nMAssay Description:Displacement of [125I]substance P human recombinant NK1 receptor expressed in CHO cells in absence of human serum albuminMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0600nMAssay Description:Displacement of [125I]substance P from human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0900nMAssay Description:Displacement of [125I]substance P human recombinant NK1 receptor expressed in CHO cells in absence of human serum albuminMore data for this Ligand-Target Pair
Affinity DataIC50: 0.100nMAssay Description:Displacement of [125I]substance P human recombinant NK1 receptor expressed in CHO cells in absence of human serum albuminMore data for this Ligand-Target Pair
Affinity DataIC50: 0.110nMAssay Description:Displacement of [125I]substance P human recombinant NK1 receptor expressed in CHO cells in absence of human serum albuminMore data for this Ligand-Target Pair
Affinity DataIC50: 0.130nMAssay Description:Displacement of [125I]substance P human recombinant NK1 receptor expressed in CHO cells in absence of human serum albuminMore data for this Ligand-Target Pair
Affinity DataIC50: 0.140nMAssay Description:Inhibition of mouse SSTR3 transfected in CHO cells assessed as inhibition of SRIF-induced reduction of cAMP accumulation after 45 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.150nMAssay Description:Displacement of [125I]substance P human recombinant NK1 receptor expressed in CHO cells in absence of human serum albuminMore data for this Ligand-Target Pair
TargetSomatostatin receptor type 3(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 0.150nMAssay Description:Antagonist activity at human SSTR3 expressed in CHO cells assessed as cAMP level by fluorescence analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 0.160nMAssay Description:Antagonist activity at mouse SSTR3 expressed in CHO cells assessed as cAMP level by fluorescence analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 0.255nMAssay Description:Displacement of [125I]substance P human recombinant NK1 receptor expressed in CHO cells in absence of human serum albuminMore data for this Ligand-Target Pair
Affinity DataIC50: 0.300nMAssay Description:Inhibition of [3H]CP-55940 binding to human recombinant CB1 receptor in CHO cellsMore data for this Ligand-Target Pair
TargetSomatostatin receptor type 3(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 0.300nMAssay Description:Antagonist activity against human recombinant SSTR3 expressed in CHO cells assessed as reduction in forskolin-induced cAMP accumulation in presence o...More data for this Ligand-Target Pair
Affinity DataIC50: 0.350nMAssay Description:Antagonist activity at mouse SSTR3 expressed in CHO cells assessed as cAMP level by fluorescence analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 0.360nMAssay Description:Displacement of [125I]SS-28 from mouse SSTR3 transfected in CHO cells after 60 to 90 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.360nMAssay Description:Antagonist activity at mouse SSTR3 expressed in CHO cells assessed as cAMP level by fluorescence analysisMore data for this Ligand-Target Pair
TargetSomatostatin receptor type 3(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 0.400nMAssay Description:Antagonist activity against human recombinant SSTR3 expressed in CHO cells assessed as reduction in forskolin-induced cAMP accumulation in presence o...More data for this Ligand-Target Pair
TargetSomatostatin receptor type 3(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 0.400nMAssay Description:Antagonist activity against human recombinant SSTR3 expressed in CHO cells assessed as reduction in forskolin-induced cAMP accumulation in presence o...More data for this Ligand-Target Pair
Affinity DataIC50: 0.410nMAssay Description:Displacement of [125I]SS-14 from mouse SSTR3 expressed in CHO cells by TopCount analyzerMore data for this Ligand-Target Pair
Affinity DataIC50: 0.410nMAssay Description:Displacement of [125I]SS-14 from mouse SSTR3 expressed in CHO cells by TopCount analyzerMore data for this Ligand-Target Pair
Affinity DataIC50: 0.460nMAssay Description:Inhibition of mouse SSTR3 transfected in CHO cells assessed as inhibition of SRIF-induced reduction of cAMP accumulation after 45 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.460nMAssay Description:Displacement of [125I]SS-28 from mouse SSTR3 transfected in CHO cells after 60 to 90 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.480nMAssay Description:Inhibition of mouse SSTR3 transfected in CHO cells assessed as inhibition of SRIF-induced reduction of cAMP accumulation after 45 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.5nMAssay Description:Inhibition of [3H]CP-55940 binding to human recombinant CB1 receptor in CHO cellsMore data for this Ligand-Target Pair
TargetSomatostatin receptor type 3(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 0.5nMAssay Description:Antagonist activity against human recombinant SSTR3 expressed in CHO cells assessed as reduction in forskolin-induced cAMP accumulation in presence o...More data for this Ligand-Target Pair
Affinity DataIC50: 0.5nMAssay Description:Displacement of [125I]SS-28 from mouse SSTR3 transfected in CHO cells after 60 to 90 minsMore data for this Ligand-Target Pair
TargetSomatostatin receptor type 3(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 0.520nMAssay Description:Antagonist activity at human SSTR3 expressed in CHO cells assessed as cAMP level by fluorescence analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 0.525nMAssay Description:Displacement of [125I]substance P human recombinant NK1 receptor expressed in CHO cells in absence of human serum albuminMore data for this Ligand-Target Pair