Affinity DataKi: 4.90nMAssay Description:Inhibition of recombinant human MAO-A using kynuramine as substrate incubated for 20 mins by spectrophotometry analysisMore data for this Ligand-Target Pair
Affinity DataKi: 5.40nMAssay Description:Inhibition of MAO-A (unknown origin)More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
Indian Institute Of Technology (Banaras Hindu University)
Curated by ChEMBL
Indian Institute Of Technology (Banaras Hindu University)
Curated by ChEMBL
Affinity DataKi: 23nMAssay Description:Mixed type inhibition of human AChE assessed as dissociation constant using varying level acetylthiocholine iodide as substrate by Dixon plot analysi...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
Indian Institute Of Technology (Banaras Hindu University)
Curated by ChEMBL
Indian Institute Of Technology (Banaras Hindu University)
Curated by ChEMBL
Affinity DataKi: 30nMAssay Description:Mixed type inhibition of human erythrocytes AChE using varying levels of acetylthiocholine iodide substrate by Dixon plot analysisMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
Indian Institute Of Technology (Banaras Hindu University)
Curated by ChEMBL
Indian Institute Of Technology (Banaras Hindu University)
Curated by ChEMBL
Affinity DataKi: 100nMAssay Description:Non-competitive inhibition of human erythrocyte AChE using acetylthiocholine iodide as substrate preincubated for 10 mins followed by substrate addit...More data for this Ligand-Target Pair
Affinity DataKi: 920nMAssay Description:Non noncompetitive inhibition of human COX-2 preincubated for 5 mins followed by arachidonic acid substrate addition by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 2.90E+3nMAssay Description:Competitive inhibition of rat MAO-BMore data for this Ligand-Target Pair
Affinity DataKi: 3.10E+3nMAssay Description:Competitive inhibition of human MAO-BMore data for this Ligand-Target Pair
Affinity DataKi: 1.50E+4nMAssay Description:Irreversible inhibition of human recombinant MAO-BMore data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: 3.08E+4nMAssay Description:Inhibition of MAO-B (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 3.10E+4nMAssay Description:Competitive inhibition of human MAO-AMore data for this Ligand-Target Pair
Affinity DataKi: 2.68E+5nMAssay Description:Irreversible inhibition of human recombinant MAO-AMore data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 0.220nMAssay Description:Inhibition of rat MAO-AMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of human MAO-BMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of human MAO-BMore data for this Ligand-Target Pair
Affinity DataIC50: 8.60nMpH: 8.0 T: 2°CAssay Description:Suitable agents like donepezil hydrochloride and tacrine hydrochloride hydrate were used as standards for this study. Buffer solution (50 mM Tris-HCl...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
Indian Institute Of Technology (Banaras Hindu University)
Curated by ChEMBL
Indian Institute Of Technology (Banaras Hindu University)
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of human erythrocyte AChE using ATCI as substrate preincubated for 30 mins followed by substrate addition measured after 30 mins by Ellman...More data for this Ligand-Target Pair
TargetCholinesterase(Equus caballus (Horse))
The Maharaja Sayajirao University Of Baroda
Curated by ChEMBL
The Maharaja Sayajirao University Of Baroda
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of equine serum BuChE using BTCI as substrate preincubated for 30 mins followed by substrate addition measured after 30 mins by Ellman ass...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of human recombinant MAO-AMore data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 10nMAssay Description:Inhibition of human recombinant MAO-AMore data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 10nMAssay Description:Inhibition of human recombinant MAO-AMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of human recombinant MAO-AMore data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 10nMAssay Description:Inhibition of human recombinant MAO-AMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of human recombinant MAO-AMore data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 10nMAssay Description:Inhibition of human recombinant MAO-AMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of MAO-B (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of human recombinant MAO-AMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of human recombinant MAO-AMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of human recombinant MAO-AMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of human recombinant MAO-AMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of human recombinant MAO-AMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of human recombinant MAO-AMore data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 10nMAssay Description:Inhibition of human recombinant MAO-AMore data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Reversible inhibition of human MAO-BMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
Indian Institute Of Technology (Banaras Hindu University)
Curated by ChEMBL
Indian Institute Of Technology (Banaras Hindu University)
Curated by ChEMBL
Affinity DataIC50: 23nMpH: 8.0 T: 2°CAssay Description:Suitable agents like donepezil hydrochloride and tacrine hydrochloride hydrate were used as standards for this study. Buffer solution (50 mM Tris-HCl...More data for this Ligand-Target Pair
TargetCholesterol side-chain cleavage enzyme, mitochondrial(Rattus norvegicus)
Lucknow University
Curated by ChEMBL
Lucknow University
Curated by ChEMBL
Affinity DataIC50: 28.6nMAssay Description:Antibacterial activity against Streptococcus faecalis by broth microdilution techniqueMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Inhibition of human MAO-BMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
Indian Institute Of Technology (Banaras Hindu University)
Curated by ChEMBL
Indian Institute Of Technology (Banaras Hindu University)
Curated by ChEMBL
Affinity DataIC50: 33nMAssay Description:Inhibition of human erythrocyte acetylcholinesterase using acetylthiocholine iodide as substrate pre-incubated for 10 mins followed by substrate addi...More data for this Ligand-Target Pair
Affinity DataIC50: 36nMAssay Description:Inhibition of MMP13 (unknown origin)More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
Indian Institute Of Technology (Banaras Hindu University)
Curated by ChEMBL
Indian Institute Of Technology (Banaras Hindu University)
Curated by ChEMBL
Affinity DataIC50: 42nMAssay Description:Inhibition of human erythrocytes AChE using acetylthiocholine iodide as substrate preincubated for 10 mins followed by substrate addition by Ellman's...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
Indian Institute Of Technology (Banaras Hindu University)
Curated by ChEMBL
Indian Institute Of Technology (Banaras Hindu University)
Curated by ChEMBL
Affinity DataIC50: 42nMAssay Description:Inhibition of human AChE by Ellman's methodMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
Indian Institute Of Technology (Banaras Hindu University)
Curated by ChEMBL
Indian Institute Of Technology (Banaras Hindu University)
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:Inhibition of human erythrocyte AChE using ATCI as substrate preincubated for 30 mins followed by substrate addition measured after 30 mins by Ellman...More data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Inhibition of human COX-2 preincubated for 5 mins followed by arachidonic acid substrate addition by colorimetric enzyme immunoassayMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
Indian Institute Of Technology (Banaras Hindu University)
Curated by ChEMBL
Indian Institute Of Technology (Banaras Hindu University)
Curated by ChEMBL
Affinity DataIC50: 54nMAssay Description:Inhibition of human erythrocytes AChE using acetylthiocholine iodide as substrate preincubated for 10 mins followed by substrate addition by Ellman's...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
Indian Institute Of Technology (Banaras Hindu University)
Curated by ChEMBL
Indian Institute Of Technology (Banaras Hindu University)
Curated by ChEMBL
Affinity DataIC50: 56nMpH: 8.0 T: 2°CAssay Description:Suitable agents like donepezil hydrochloride and tacrine hydrochloride hydrate were used as standards for this study. Buffer solution (50 mM Tris-HCl...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
Indian Institute Of Technology (Banaras Hindu University)
Curated by ChEMBL
Indian Institute Of Technology (Banaras Hindu University)
Curated by ChEMBL
Affinity DataIC50: 58nMAssay Description:Inhibition of human AChE by Ellman's methodMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
Indian Institute Of Technology (Banaras Hindu University)
Curated by ChEMBL
Indian Institute Of Technology (Banaras Hindu University)
Curated by ChEMBL
Affinity DataIC50: 69nMAssay Description:Inhibition of human AChE by Ellman's methodMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
Indian Institute Of Technology (Banaras Hindu University)
Curated by ChEMBL
Indian Institute Of Technology (Banaras Hindu University)
Curated by ChEMBL
Affinity DataIC50: 74nMAssay Description:Inhibition of human erythrocytes AChE using acetylthiocholine iodide as substrate preincubated for 10 mins followed by substrate addition by Ellman's...More data for this Ligand-Target Pair
TargetCholinesterase(Homo sapiens (Human))
Indian Institute Of Technology (Banaras Hindu University)
Curated by ChEMBL
Indian Institute Of Technology (Banaras Hindu University)
Curated by ChEMBL
Affinity DataIC50: 82nMAssay Description:Inhibition of human BChE by Ellman's methodMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
Indian Institute Of Technology (Banaras Hindu University)
Curated by ChEMBL
Indian Institute Of Technology (Banaras Hindu University)
Curated by ChEMBL
Affinity DataIC50: 89nMAssay Description:Inhibition of human erythrocytes AChE using acetylthiocholine iodide as substrate preincubated for 10 mins followed by substrate addition by Ellman's...More data for this Ligand-Target Pair