Affinity DataKi: 7.00E+3nMAssay Description:Inhibition of Matrix metalloprotease-1 (MMP1)More data for this Ligand-Target Pair
Affinity DataIC50: 0.0160nMAssay Description:Inhibition of Matrix metalloproteinase-13More data for this Ligand-Target Pair
Target72 kDa type IV collagenase(Homo sapiens (Human))
Institut De Recherches Servier
Curated by ChEMBL
Institut De Recherches Servier
Curated by ChEMBL
Affinity DataIC50: 0.0600nMAssay Description:Inhibitory activity against matrix metalloprotease-2 (MMP2)More data for this Ligand-Target Pair
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Universite Catholique De Louvain
Curated by ChEMBL
Universite Catholique De Louvain
Curated by ChEMBL
Affinity DataIC50: 0.100nMAssay Description:Inhibition of human integrin alphav beta3 receptor by biotinylated vitronectin competitive binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.100nMAssay Description:Displacement of vitronectin from Human integrin alphaV-beta3More data for this Ligand-Target Pair
Target72 kDa type IV collagenase(Homo sapiens (Human))
Institut De Recherches Servier
Curated by ChEMBL
Institut De Recherches Servier
Curated by ChEMBL
Affinity DataIC50: 0.100nMAssay Description:Inhibition of Matrix metalloproteinase-2More data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:Inhibition of matrix metalloprotease-9More data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:Inhibition of matrix metalloprotease-9More data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:Inhibition of Matrix metalloproteinase-9More data for this Ligand-Target Pair
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Universite Catholique De Louvain
Curated by ChEMBL
Universite Catholique De Louvain
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Displacement of vitronectin from Human integrin alphaV-beta3More data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:Displacement of fibrinogen from Human integrin alphaIIb-beta3More data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:Inhibitory activity against matrix metalloprotease-9 (MMP9)More data for this Ligand-Target Pair
Affinity DataIC50: 0.300nMAssay Description:Displacement of fibrinogen from Human integrin alphaIIb-beta3More data for this Ligand-Target Pair
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Universite Catholique De Louvain
Curated by ChEMBL
Universite Catholique De Louvain
Curated by ChEMBL
Affinity DataIC50: 0.300nMAssay Description:Displacement of vitronectin from human integrin alphaV-beta5More data for this Ligand-Target Pair
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Universite Catholique De Louvain
Curated by ChEMBL
Universite Catholique De Louvain
Curated by ChEMBL
Affinity DataIC50: 0.300nMAssay Description:Displacement of vitronectin from human integrin alphaV-beta5More data for this Ligand-Target Pair
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Universite Catholique De Louvain
Curated by ChEMBL
Universite Catholique De Louvain
Curated by ChEMBL
Affinity DataIC50: 0.300nMAssay Description:Inhibition of human integrin alphav beta3 receptor by biotinylated vitronectin competitive binding assayMore data for this Ligand-Target Pair
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Universite Catholique De Louvain
Curated by ChEMBL
Universite Catholique De Louvain
Curated by ChEMBL
Affinity DataIC50: 0.300nMAssay Description:Inhibition of human integrin alphav beta3 receptor by biotinylated vitronectin competitive binding assayMore data for this Ligand-Target Pair
Target72 kDa type IV collagenase(Homo sapiens (Human))
Institut De Recherches Servier
Curated by ChEMBL
Institut De Recherches Servier
Curated by ChEMBL
Affinity DataIC50: 0.400nMAssay Description:Inhibition of Matrix metalloproteinase-2More data for this Ligand-Target Pair
Target72 kDa type IV collagenase(Homo sapiens (Human))
Institut De Recherches Servier
Curated by ChEMBL
Institut De Recherches Servier
Curated by ChEMBL
Affinity DataIC50: 0.5nMAssay Description:Inhibitory activity against matrix metalloprotease-2 (MMP2)More data for this Ligand-Target Pair
Target72 kDa type IV collagenase(Homo sapiens (Human))
Institut De Recherches Servier
Curated by ChEMBL
Institut De Recherches Servier
Curated by ChEMBL
Affinity DataIC50: 0.5nMAssay Description:Inhibition of Matrix metalloproteinase-2More data for this Ligand-Target Pair
Affinity DataIC50: 0.5nMAssay Description:Displacement of vitronectin from human integrin alphaV-beta5More data for this Ligand-Target Pair
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Universite Catholique De Louvain
Curated by ChEMBL
Universite Catholique De Louvain
Curated by ChEMBL
Affinity DataIC50: 0.5nMAssay Description:Inhibition of human integrin alphav beta3 receptor by biotinylated vitronectin competitive binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.5nMAssay Description:Inhibitory concentration required against matrix metalloprotease-9 (MMP-9 gelatinase B)More data for this Ligand-Target Pair
Affinity DataIC50: 0.5nMAssay Description:Inhibitory activity against matrix metalloprotease-9 (MMP9)More data for this Ligand-Target Pair
Target72 kDa type IV collagenase(Homo sapiens (Human))
Institut De Recherches Servier
Curated by ChEMBL
Institut De Recherches Servier
Curated by ChEMBL
Affinity DataIC50: 0.5nMAssay Description:Inhibition of Matrix metalloproteinase-2More data for this Ligand-Target Pair
Affinity DataIC50: 0.600nMAssay Description:Inhibition of Matrix metalloproteinase-13More data for this Ligand-Target Pair
Affinity DataIC50: 0.600nMAssay Description:Inhibition of Matrix metalloproteinase-9More data for this Ligand-Target Pair
Affinity DataIC50: 0.600nMAssay Description:Inhibition of Matrix metalloproteinase-9More data for this Ligand-Target Pair
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Universite Catholique De Louvain
Curated by ChEMBL
Universite Catholique De Louvain
Curated by ChEMBL
Affinity DataIC50: 0.600nMAssay Description:Inhibition of human integrin alphav beta3 receptor by biotinylated vitronectin competitive binding assayMore data for this Ligand-Target Pair
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Universite Catholique De Louvain
Curated by ChEMBL
Universite Catholique De Louvain
Curated by ChEMBL
Affinity DataIC50: 0.600nMAssay Description:Displacement of vitronectin from human integrin alphaV-beta5More data for this Ligand-Target Pair
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Universite Catholique De Louvain
Curated by ChEMBL
Universite Catholique De Louvain
Curated by ChEMBL
Affinity DataIC50: 0.600nMAssay Description:Inhibition of human integrin alphav beta3 receptor by biotinylated vitronectin competitive binding assayMore data for this Ligand-Target Pair
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Universite Catholique De Louvain
Curated by ChEMBL
Universite Catholique De Louvain
Curated by ChEMBL
Affinity DataIC50: 0.700nMAssay Description:Inhibition of human integrin alphav beta3 receptor by biotinylated vitronectin competitive binding assayMore data for this Ligand-Target Pair
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Universite Catholique De Louvain
Curated by ChEMBL
Universite Catholique De Louvain
Curated by ChEMBL
Affinity DataIC50: 0.700nMAssay Description:Inhibition of human integrin alphav beta3 receptor by biotinylated vitronectin competitive binding assayMore data for this Ligand-Target Pair
Target72 kDa type IV collagenase(Homo sapiens (Human))
Institut De Recherches Servier
Curated by ChEMBL
Institut De Recherches Servier
Curated by ChEMBL
Affinity DataIC50: 0.700nMAssay Description:Inhibition of matrix metalloprotease-2More data for this Ligand-Target Pair
Target72 kDa type IV collagenase(Homo sapiens (Human))
Institut De Recherches Servier
Curated by ChEMBL
Institut De Recherches Servier
Curated by ChEMBL
Affinity DataIC50: 0.700nMAssay Description:Inhibition of matrix metalloprotease-2More data for this Ligand-Target Pair
Affinity DataIC50: 0.700nMAssay Description:Inhibition of matrix metalloprotease-3More data for this Ligand-Target Pair
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Universite Catholique De Louvain
Curated by ChEMBL
Universite Catholique De Louvain
Curated by ChEMBL
Affinity DataIC50: 0.800nMAssay Description:Inhibition of human integrin alphav beta3 receptor by biotinylated vitronectin competitive binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.800nMAssay Description:Displacement of fibrinogen from Human integrin alphaIIb-beta3More data for this Ligand-Target Pair
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Universite Catholique De Louvain
Curated by ChEMBL
Universite Catholique De Louvain
Curated by ChEMBL
Affinity DataIC50: 0.800nMAssay Description:Inhibition of human integrin alphav beta3 receptor by biotinylated vitronectin competitive binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.900nMAssay Description:Displacement of fibrinogen from Human integrin alphaIIb-beta3More data for this Ligand-Target Pair
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Universite Catholique De Louvain
Curated by ChEMBL
Universite Catholique De Louvain
Curated by ChEMBL
Affinity DataIC50: 0.900nMAssay Description:Inhibition of human integrin alphav beta3 receptor by biotinylated vitronectin competitive binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of Matrix metalloproteinase-9More data for this Ligand-Target Pair
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Institut De Recherches Servier
Curated by ChEMBL
Institut De Recherches Servier
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of farnesyltransferaseMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:Inhibitory activity against matrix metalloprotease-3 (MMP3)More data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:Inhibition of Matrix metalloproteinase-3More data for this Ligand-Target Pair
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Universite Catholique De Louvain
Curated by ChEMBL
Universite Catholique De Louvain
Curated by ChEMBL
Affinity DataIC50: 1.10nMAssay Description:Inhibition of human integrin alphav beta3 receptor by biotinylated vitronectin competitive binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:Inhibition of Matrix metalloproteinase-3More data for this Ligand-Target Pair
Affinity DataIC50: 1.20nMAssay Description:Inhibitory activity against matrix metalloprotease-13 (MMP13)More data for this Ligand-Target Pair
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Universite Catholique De Louvain
Curated by ChEMBL
Universite Catholique De Louvain
Curated by ChEMBL
Affinity DataIC50: 1.20nMAssay Description:Inhibition of human integrin alphav beta3 receptor by biotinylated vitronectin competitive binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20nMAssay Description:Inhibitory activity against matrix metalloprotease-3 (MMP3)More data for this Ligand-Target Pair