Affinity DataKi: 0.220nMAssay Description:Antagonist activity at human adenosine A2A receptorMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Bristol-Myers Squibb
Curated by ChEMBL
Bristol-Myers Squibb
Curated by ChEMBL
Affinity DataKi: 0.900nMAssay Description:Inhibition of recombinant human 11beta-HSD1 expressed in HEK293 cell microsomes using [3H]cortisone as substrate after 4 hrs by homogeneous immuno-ra...More data for this Ligand-Target Pair
TargetWD repeat-containing protein 5(Homo sapiens (Human))
Zhejiang Sci-Tech University
Curated by ChEMBL
Zhejiang Sci-Tech University
Curated by ChEMBL
Affinity DataKi: <1nMAssay Description:Displacement of 5-FAM labelled tracer from WDR5 (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetWD repeat-containing protein 5(Homo sapiens (Human))
Zhejiang Sci-Tech University
Curated by ChEMBL
Zhejiang Sci-Tech University
Curated by ChEMBL
Affinity DataKi: <1nMAssay Description:Displacement of 5-FAM labelled tracer from WDR5 (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetWD repeat-containing protein 5(Homo sapiens (Human))
Zhejiang Sci-Tech University
Curated by ChEMBL
Zhejiang Sci-Tech University
Curated by ChEMBL
Affinity DataKi: <1nMAssay Description:Displacement of 5-FAM labelled tracer from WDR5 (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.40nMAssay Description:Agonist activity at dopamine D3 receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Agonist activity at dopamine D2 receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 2.30nMAssay Description:Antagonist activity at adenosine A2A receptor (unknown origin)More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Zhejiang Sci-Tech University
Curated by ChEMBL
Zhejiang Sci-Tech University
Curated by ChEMBL
Affinity DataKi: 2.40nMAssay Description:Inhibition of PTP1B (unknown origin)More data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Georgia Institute Of Technology
Curated by ChEMBL
Georgia Institute Of Technology
Curated by ChEMBL
Affinity DataKi: 2.5nMAssay Description:Displacement of [3H]WIN-35428 from DAT in Sprague-Dawley rat striatumMore data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Agonist activity at dopamine D1 receptor (unknown origin)More data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Georgia Institute Of Technology
Curated by ChEMBL
Georgia Institute Of Technology
Curated by ChEMBL
Affinity DataKi: 3.40nMAssay Description:Displacement of [3H]WIN-35428 from DAT in Sprague-Dawley rat striatumMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Georgia Institute Of Technology
Curated by ChEMBL
Georgia Institute Of Technology
Curated by ChEMBL
Affinity DataKi: 3.40nMAssay Description:Displacement of [3H]WIN-35428 from DAT in Sprague-Dawley rat striatumMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Bristol-Myers Squibb
Curated by ChEMBL
Bristol-Myers Squibb
Curated by ChEMBL
Affinity DataKi: 3.80nMAssay Description:Inhibition of 11beta-HSD1 in human microsomes using [3H]cortisone as substrate preincubated for 10 mins followed by substrate addition measured after...More data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Georgia Institute Of Technology
Curated by ChEMBL
Georgia Institute Of Technology
Curated by ChEMBL
Affinity DataKi: 3.90nMAssay Description:Displacement of [3H]WIN-35428 from DAT in Sprague-Dawley rat striatumMore data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:Antagonist activity at human adenosine A2A receptorMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Georgia Institute Of Technology
Curated by ChEMBL
Georgia Institute Of Technology
Curated by ChEMBL
Affinity DataKi: 4.10nMAssay Description:Displacement of [3H]WIN-35428 from DAT in Sprague-Dawley rat striatumMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Georgia Institute Of Technology
Curated by ChEMBL
Georgia Institute Of Technology
Curated by ChEMBL
Affinity DataKi: 4.80nMAssay Description:Displacement of [3H]WIN-35428 from DAT in Sprague-Dawley rat striatumMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Georgia Institute Of Technology
Curated by ChEMBL
Georgia Institute Of Technology
Curated by ChEMBL
Affinity DataKi: 5.5nMAssay Description:Displacement of [3H]WIN-35428 from DAT in Sprague-Dawley rat striatumMore data for this Ligand-Target Pair
Affinity DataKi: 6.30nMAssay Description:Antagonist activity at rat adenosine A1 receptorMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Bristol-Myers Squibb
Curated by ChEMBL
Bristol-Myers Squibb
Curated by ChEMBL
Affinity DataKi: 8nMAssay Description:Inhibition of human 11beta-HSD-1More data for this Ligand-Target Pair
Affinity DataKi: 8nMAssay Description:Binding affinity PSMA (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 9.5nMAssay Description:Antagonist activity at rat adenosine A2A receptorMore data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Antagonist activity at rat adenosine A2A receptorMore data for this Ligand-Target Pair
Affinity DataKi: 11nMAssay Description:Antagonist activity at human adenosine A2A receptorMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Georgia Institute Of Technology
Curated by ChEMBL
Georgia Institute Of Technology
Curated by ChEMBL
Affinity DataKi: 11nMAssay Description:Displacement of [3H]WIN-35428 from DAT in Sprague-Dawley rat striatumMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Georgia Institute Of Technology
Curated by ChEMBL
Georgia Institute Of Technology
Curated by ChEMBL
Affinity DataKi: 14nMAssay Description:Displacement of [3H]WIN-35428 from DAT in Sprague-Dawley rat striatumMore data for this Ligand-Target Pair
TargetBeta-galactoside alpha-2,6-sialyltransferase 1(Homo sapiens (Human))
Peking University
Curated by ChEMBL
Peking University
Curated by ChEMBL
Affinity DataKi: 16nMAssay Description:Inhibition of recombinant human N-terminal His-tagged ST6Gal-1 (44 to 406 residues) using CMP-Neu5Ac as substrate after 20 mins by UV/RP-HPLC methodMore data for this Ligand-Target Pair
TargetBeta-galactoside alpha-2,6-sialyltransferase 1(Homo sapiens (Human))
Peking University
Curated by ChEMBL
Peking University
Curated by ChEMBL
Affinity DataKi: 16nMAssay Description:Inhibition of recombinant human N-terminal His-tagged ST6Gal-1 (44 to 406 residues) using CMP-Neu5Ac as substrate after 20 mins by UV/RP-HPLC methodMore data for this Ligand-Target Pair
TargetBeta-galactoside alpha-2,6-sialyltransferase 1(Homo sapiens (Human))
Peking University
Curated by ChEMBL
Peking University
Curated by ChEMBL
Affinity DataKi: 19nMAssay Description:Inhibition of recombinant human N-terminal His-tagged ST6Gal-1 (44 to 406 residues) using CMP-Neu5Ac as substrate after 20 mins by UV/RP-HPLC methodMore data for this Ligand-Target Pair
TargetBeta-galactoside alpha-2,6-sialyltransferase 1(Homo sapiens (Human))
Peking University
Curated by ChEMBL
Peking University
Curated by ChEMBL
Affinity DataKi: 19nMAssay Description:Competitive inhibition of human recombinant ST6Gal-1 using CMP-Neu5Ac and p-nitrophenyl LacNAc as donar and acceptor by Lineweaver-Burk double recipr...More data for this Ligand-Target Pair
TargetBeta-galactoside alpha-2,6-sialyltransferase 1(Homo sapiens (Human))
Peking University
Curated by ChEMBL
Peking University
Curated by ChEMBL
Affinity DataKi: 20nMAssay Description:Inhibition of recombinant human N-terminal His-tagged ST6Gal-1 (44 to 406 residues) using CMP-Neu5Ac as substrate after 20 mins by UV/RP-HPLC methodMore data for this Ligand-Target Pair
TargetBeta-galactoside alpha-2,6-sialyltransferase 1(Homo sapiens (Human))
Peking University
Curated by ChEMBL
Peking University
Curated by ChEMBL
Affinity DataKi: 20nMAssay Description:Inhibition of recombinant human N-terminal His-tagged ST6Gal-1 (44 to 406 residues) using CMP-Neu5Ac as substrate after 20 mins by UV/RP-HPLC methodMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
Zhejiang Sci-Tech University
Curated by ChEMBL
Zhejiang Sci-Tech University
Curated by ChEMBL
Affinity DataKi: 24nMAssay Description:Inhibition of TCPTP (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 27nMAssay Description:Agonist activity at dopamine D2 receptor (unknown origin)More data for this Ligand-Target Pair
TargetBromodomain-containing protein 4(Homo sapiens (Human))
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataKi: 27nMAssay Description:Inhibition of BRD4 BD1 (unknown origin) using FAM-labeled JQ-1 as fluorescent substrate assessed as inhibition constant incubated for 30 mins by comp...More data for this Ligand-Target Pair
TargetBeta-galactoside alpha-2,6-sialyltransferase 1(Homo sapiens (Human))
Peking University
Curated by ChEMBL
Peking University
Curated by ChEMBL
Affinity DataKi: 28nMAssay Description:Inhibition of recombinant human N-terminal His-tagged ST6Gal-1 (44 to 406 residues) using CMP-Neu5Ac as substrate after 20 mins by UV/RP-HPLC methodMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Georgia Institute Of Technology
Curated by ChEMBL
Georgia Institute Of Technology
Curated by ChEMBL
Affinity DataKi: 28nMAssay Description:Displacement of [3H]WIN-35428 from DAT in Sprague-Dawley rat striatumMore data for this Ligand-Target Pair
TargetBeta-galactoside alpha-2,6-sialyltransferase 1(Homo sapiens (Human))
Peking University
Curated by ChEMBL
Peking University
Curated by ChEMBL
Affinity DataKi: 28nMAssay Description:Competitive inhibition of human recombinant ST6Gal-1 using CMP-Neu5Ac and p-nitrophenyl LacNAc as donar and acceptor by Lineweaver-Burk double recipr...More data for this Ligand-Target Pair
TargetBeta-galactoside alpha-2,6-sialyltransferase 1(Homo sapiens (Human))
Peking University
Curated by ChEMBL
Peking University
Curated by ChEMBL
Affinity DataKi: 28nMAssay Description:Inhibition of recombinant human N-terminal His-tagged ST6Gal-1 (44 to 406 residues) using CMP-Neu5Ac as substrate after 20 mins by UV/RP-HPLC methodMore data for this Ligand-Target Pair
Affinity DataKi: 28nMAssay Description:Displacement of [3H]nisoxetine from NET in Sprague-Dawley rat cortical tissueMore data for this Ligand-Target Pair
TargetBeta-galactoside alpha-2,6-sialyltransferase 1(Homo sapiens (Human))
Peking University
Curated by ChEMBL
Peking University
Curated by ChEMBL
Affinity DataKi: 28nMAssay Description:Competitive inhibition of human recombinant ST6Gal-1 using CMP-Neu5Ac and p-nitrophenyl LacNAc as donar and acceptor by Lineweaver-Burk double recipr...More data for this Ligand-Target Pair
Affinity DataKi: 28nMAssay Description:Displacement of [3H]nisoxetine from NET in Sprague-Dawley rat cortical tissueMore data for this Ligand-Target Pair
TargetBeta-galactoside alpha-2,6-sialyltransferase 1(Homo sapiens (Human))
Peking University
Curated by ChEMBL
Peking University
Curated by ChEMBL
Affinity DataKi: 29nMAssay Description:Inhibition of recombinant human N-terminal His-tagged ST6Gal-1 (44 to 406 residues) using CMP-Neu5Ac as substrate after 20 mins by UV/RP-HPLC methodMore data for this Ligand-Target Pair
TargetBeta-galactoside alpha-2,6-sialyltransferase 1(Homo sapiens (Human))
Peking University
Curated by ChEMBL
Peking University
Curated by ChEMBL
Affinity DataKi: 29nMAssay Description:Inhibition of recombinant human N-terminal His-tagged ST6Gal-1 (44 to 406 residues) using CMP-Neu5Ac as substrate after 20 mins by UV/RP-HPLC methodMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Georgia Institute Of Technology
Curated by ChEMBL
Georgia Institute Of Technology
Curated by ChEMBL
Affinity DataKi: 35nMAssay Description:Displacement of [3H]WIN-35428 from DAT in Sprague-Dawley rat striatumMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Georgia Institute Of Technology
Curated by ChEMBL
Georgia Institute Of Technology
Curated by ChEMBL
Affinity DataKi: 36nMAssay Description:Displacement of [3H]WIN-35428 from DAT in Sprague-Dawley rat striatumMore data for this Ligand-Target Pair
Affinity DataKi: 54nMAssay Description:Antagonist activity at human adenosine A2A receptorMore data for this Ligand-Target Pair
TargetBeta-galactoside alpha-2,6-sialyltransferase 1(Homo sapiens (Human))
Peking University
Curated by ChEMBL
Peking University
Curated by ChEMBL
Affinity DataKi: 60nMAssay Description:Inhibition of recombinant human N-terminal His-tagged ST6Gal-1 (44 to 406 residues) using CMP-Neu5Ac as substrate after 20 mins by UV/RP-HPLC methodMore data for this Ligand-Target Pair
TargetBeta-galactoside alpha-2,6-sialyltransferase 1(Homo sapiens (Human))
Peking University
Curated by ChEMBL
Peking University
Curated by ChEMBL
Affinity DataKi: 60nMAssay Description:Inhibition of recombinant human N-terminal His-tagged ST6Gal-1 (44 to 406 residues) using CMP-Neu5Ac as substrate after 20 mins by UV/RP-HPLC methodMore data for this Ligand-Target Pair