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Found 7 Enz. Inhib. hit(s) with Target = 'WD repeat-containing protein 5' and Ligand = 'BDBM200723'
TargetWD repeat-containing protein 5(Homo sapiens (Human))
Zhejiang Sci-Tech University

Curated by ChEMBL
LigandPNGBDBM200723(US9233086, 10L)
Affinity DataKi: <1nMAssay Description:Displacement of 5-FAM labelled tracer from WDR5 (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetWD repeat-containing protein 5(Homo sapiens (Human))
Zhejiang Sci-Tech University

Curated by ChEMBL
LigandPNGBDBM200723(US9233086, 10L)
Affinity DataIC50:  1.70nMAssay Description:Inhibition of 10mer-Thr-FAM probe binding to human WDR5 after 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetWD repeat-containing protein 5(Homo sapiens (Human))
Zhejiang Sci-Tech University

Curated by ChEMBL
LigandPNGBDBM200723(US9233086, 10L)
Affinity DataIC50:  2.40nMAssay Description:Inhibition of fluorescence-labeled Ac-ARA peptide binding to WDR5 (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetWD repeat-containing protein 5(Homo sapiens (Human))
Zhejiang Sci-Tech University

Curated by ChEMBL
LigandPNGBDBM200723(US9233086, 10L)
Affinity DataIC50:  2.40nMAssay Description:Binding affinity to WDR5 (unknown origin) fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetWD repeat-containing protein 5(Homo sapiens (Human))
Zhejiang Sci-Tech University

Curated by ChEMBL
LigandPNGBDBM200723(US9233086, 10L)
Affinity DataIC50:  2.40nMAssay Description:Displacement of fluorescence-labelled Ac-ARA peptide from WDR5 (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetWD repeat-containing protein 5(Homo sapiens (Human))
Zhejiang Sci-Tech University

Curated by ChEMBL
LigandPNGBDBM200723(US9233086, 10L)
Affinity DataIC50:  2.40nMAssay Description:Inhibition of WDR5 (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetWD repeat-containing protein 5(Homo sapiens (Human))
Zhejiang Sci-Tech University

Curated by ChEMBL
LigandPNGBDBM200723(US9233086, 10L)
Affinity DataIC50:  2.40nMAssay Description:Inhibition of C-terminal 5-FAM-WIN peptide binding to N-terminal His-tagged WDR5 (24 to 334 residues) (unknown origin) expressed in Rosetta2-(DE3) pL...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed