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Found 662 with Last Name = 'zhang' and Initial = 'gm'
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50334730(3-(Naphthalen-1-ylsulfonyl)-5-(piperazin-1-ylmethy...)
Affinity DataKi:  0.240nMAssay Description:Displacement of [3H]-LSD from cloned human 5-HT6 receptor expressed in human HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50300820(CHEMBL565723 | N-(2-{3-[(3-Chlorophenyl)sulfonyl]-...)
Affinity DataKi:  0.300nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM28574(1-sulfonylindazole, 6c | 3-amino-N-[1-(naphthalene...)
Affinity DataKi:  0.5nM ΔG°:  -52.6kJ/molepH: 7.4 T: 2°CAssay Description:Competition experiments were performed in the presence radioligand with membrane protein (obtained from cells expressing the receptor) and test compo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50334734(3-(Naphthalen-2-ylsulfonyl)-N-(piperidin-4-yl)-1H-...)
Affinity DataKi:  0.600nMAssay Description:Displacement of [3H]-LSD from cloned human 5-HT6 receptor expressed in human HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50334731(CHEMBL1642851 | [3-(Naphthalen-1-sulfonyl)-1H-inda...)
Affinity DataKi:  0.700nMAssay Description:Displacement of [3H]-LSD from cloned human 5-HT6 receptor expressed in human HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50217902(3-[(6-chloroimidazo[2,1-b][1,3]thiazol-5-yl)sulfon...)
Affinity DataKi:  0.700nMAssay Description:Displacement of [3H]LSD from cloned human 5HT6 expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50217922(3-[(6-chloroimidazo[2,1-b][1,3]thiazol-5-yl)sulfon...)
Affinity DataKi:  0.700nMAssay Description:Displacement of [3H]LSD from cloned human 5HT6 expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50334754(CHEMBL1642883 | N-(Piperidin-4-yl)-3-(m-tolylsulfo...)
Affinity DataKi:  0.800nMAssay Description:Displacement of [3H]-LSD from cloned human 5-HT6 receptor expressed in human HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50217909(3-(6-chloro-imidazo[2,1-b]thiazole-5-sulfonyl)-1-(...)
Affinity DataKi:  0.800nMAssay Description:Displacement of [3H]LSD from cloned human 5HT6 expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50217891(3-(3-bromo-benzenesulfonyl)-1-(1-methyl-pyrrolidin...)
Affinity DataKi:  0.900nMAssay Description:Displacement of [3H]LSD from cloned human 5HT6 expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50300842(CHEMBL565724 | N-(2-{3-[(6-Chloroimidazo[2,1-b][1,...)
Affinity DataKi:  0.900nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50300845(CHEMBL565746 | N-(2-{3-[(6-Chloroimidazo[2,1-b][1,...)
Affinity DataKi:  0.900nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50330507(5-(4-Methylpiperazin-1-yl)-3-(m-tolylsulfonyl)-1H-...)
Affinity DataKi:  0.900nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50334733(3-(4-Isopropylphenylsulfonyl)-N-(piperidin-4-yl)-1...)
Affinity DataKi:  1nMAssay Description:Displacement of [3H]-LSD from cloned human 5-HT6 receptor expressed in human HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50300843(CHEMBL565976 | N-(2-{3-[(3-Fluorophenyl)sulfonyl]-...)
Affinity DataKi:  1nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50334732(3-(3-Chlorophenylsulfonyl)-N-(piperidin-4-yl)-1H-i...)
Affinity DataKi:  1nMAssay Description:Displacement of [3H]-LSD from cloned human 5-HT6 receptor expressed in human HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50217904(3-(5-chloro-thiophene-2-sulfonyl)-1-pyrrolidin-3-y...)
Affinity DataKi:  1nMAssay Description:Displacement of [3H]LSD from cloned human 5HT6 expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50300838(CHEMBL565552 | N,N-Dimethyl-N-{2-[3-(1-naphthylsul...)
Affinity DataKi:  1nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50330538(3-(3-Chlorophenylsulfonyl)-5-(4-methylpiperazin-1-...)
Affinity DataKi:  1nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50217900(3-(6-chloro-imidazo[2,1-b]thiazole-5-sulfonyl)-1-p...)
Affinity DataKi:  1nMAssay Description:Displacement of [3H]LSD from cloned human 5HT6 expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM21351(4-{[3-(2-aminoethyl)-1H-indole-1-]sulfonyl}aniline...)
Affinity DataKi:  1nM ΔG°:  -50.9kJ/mole EC50:  91nMpH: 7.4 T: 2°CAssay Description:IC50 values for each test compound were determined from nonlinear regression analysis of data collected from ligand binding experiments. The inhibiti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50330512(3-(Naphthalen-1-ylsulfonyl)-5-(piperazin-1-yl)-1H-...)
Affinity DataKi:  1.10nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50330505(3-(3-Methoxyphenylsulfonyl)-5-(4-methylpiperazin-1...)
Affinity DataKi:  1.10nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50334725(CHEMBL1642866 | N-(3-(Naphthalen-1-ylsulfonyl)-1H-...)
Affinity DataKi:  1.10nMAssay Description:Displacement of [3H]-LSD from cloned human 5-HT6 receptor expressed in human HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM28575(1-sulfonylindazole, 6d | 3-(methylamino)-N-[1-(nap...)
Affinity DataKi:  1.20nM ΔG°:  -50.4kJ/molepH: 7.4 T: 2°CAssay Description:Competition experiments were performed in the presence radioligand with membrane protein (obtained from cells expressing the receptor) and test compo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50217883(3-[(5-chlorothien-2-yl)sulfonyl]-1-piperidin-3-yl-...)
Affinity DataKi:  1.20nMAssay Description:Displacement of [3H]LSD from cloned human 5HT6 expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50217916(3-[(3-chlorophenyl)sulfonyl]-1-piperidin-3-yl-1Hpy...)
Affinity DataKi:  1.30nMAssay Description:Displacement of [3H]LSD from cloned human 5HT6 expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM28583(5-chloro-N-[4-methoxy-3-(piperazin-1-yl)phenyl]-3-...)
Affinity DataKi:  1.30nMAssay Description:Displacement of [3H]LSD from human 5HT6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50217920(3-(3-bromo-benzenesulfonyl)-1-pyrrolidin-3-yl-1Hpy...)
Affinity DataKi:  1.30nMAssay Description:Displacement of [3H]LSD from cloned human 5HT6 expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM28580(1-sulfonylindazole, 7b | N-[1-(naphthalene-1-sulfo...)
Affinity DataKi:  1.30nM ΔG°:  -50.2kJ/molepH: 7.4 T: 2°CAssay Description:Competition experiments were performed in the presence radioligand with membrane protein (obtained from cells expressing the receptor) and test compo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50217893(1-pyrrolidin-3-yl-3-(3-trifluoromethyl-benzenesulf...)
Affinity DataKi:  1.30nMAssay Description:Displacement of [3H]LSD from cloned human 5HT6 expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50313121(3-(3-chlorophenylsulfonyl)-1-(1-methylpyrrolidin-3...)
Affinity DataKi:  1.30nMAssay Description:Displacement of [3H]LSD from human 5-HT6 receptor expressed in human HeLa cells after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50217928(3-(6-chloro-imidazo[2,1-b]thiazole-5-sulfonyl)-1-(...)
Affinity DataKi:  1.40nMAssay Description:Displacement of [3H]LSD from cloned human 5HT6 expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50334747(CHEMBL1642849 | N1-(3-(Naphthalen-1-ylsulfonyl)-1H...)
Affinity DataKi:  1.40nMAssay Description:Displacement of [3H]-LSD from cloned human 5-HT6 receptor expressed in human HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50330523(1-isobutyl-5-(4-methylpiperazin-1-yl)-3-(naphthale...)
Affinity DataKi:  1.40nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50217925(3-(3-fluoro-benzenesulfonyl)-1-(1-methyl-pyrrolidi...)
Affinity DataKi:  1.40nMAssay Description:Displacement of [3H]LSD from cloned human 5HT6 expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50334720(3-Amino-N-[3-(naphthalen-1-sulfonyl)-1H-indazol-5-...)
Affinity DataKi:  1.5nMAssay Description:Displacement of [3H]-LSD from cloned human 5-HT6 receptor expressed in human HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50313125(8-(1-(pyrrolidin-3-yl)-1H-indol-3-ylsulfonyl)quino...)
Affinity DataKi:  1.5nMAssay Description:Displacement of [3H]LSD from human 5-HT6 receptor expressed in human HeLa cells after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50334757(CHEMBL1642887 | N-(Piperidin-4-yl)-3-(4-(trifluoro...)
Affinity DataKi:  1.5nMAssay Description:Displacement of [3H]-LSD from cloned human 5-HT6 receptor expressed in human HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50217880(3-(3-chloro-benzenesulfonyl)-1-pyrrolidin-3-yl-1Hp...)
Affinity DataKi:  1.5nMAssay Description:Displacement of [3H]LSD from cloned human 5HT6 expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50217924(3-(3-chloro-benzenesulfonyl)-1-(1-methyl-pyrrolidi...)
Affinity DataKi:  1.5nMAssay Description:Displacement of [3H]LSD from cloned human 5HT6 expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50300839(2-[3-(1-Naphthylsulfonyl)-1H-pyrrolo[2,3-b]pyridin...)
Affinity DataKi:  1.60nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50330511(5-(4-Methylpiperazin-1-yl)-3-(1-naphthalenesulfony...)
Affinity DataKi:  1.60nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50330516(1-methyl-3-(naphthalen-1-ylsulfonyl)-5-(piperazin-...)
Affinity DataKi:  1.60nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50330517(1-ethyl-5-(4-methylpiperazin-1-yl)-3-(naphthalen-1...)
Affinity DataKi:  1.70nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50330535(3-(3-Fluorophenylsulfonyl)-5-(4-methylpiperazin-1-...)
Affinity DataKi:  1.70nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50217913(3-[(6-chloroimidazo[2,1-b][1,3]thiazol-5-yl)sulfon...)
Affinity DataKi:  1.70nMAssay Description:Displacement of [3H]LSD from cloned human 5HT6 expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50330515(1-methyl-5-(4-methylpiperazin-1-yl)-3-(naphthalen-...)
Affinity DataKi:  1.70nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50303164(1-(1-(2-(dimethylamino)ethyl)-3-(naphthalen-1-ylsu...)
Affinity DataKi:  1.70nMAssay Description:Displacement of [3H]LSD from human HT6 receptor expressed in human HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50334716(3-(Naphthalen-1-ylsulfonyl)-N-(piperidin-5-yl)-1H-...)
Affinity DataKi:  1.70nMAssay Description:Displacement of [3H]-LSD from cloned human 5-HT6 receptor expressed in human HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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