Affinity DataIC50: 1.40nMAssay Description:Inhibition of human recombinant LTA4H hydrolysis assessed as inhibition of LTB4 formation by LC-MS/MSChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of human recombinant LTA4H hydrolysis assessed as inhibition of LTB4 formation by LC-MS/MSChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:Inhibition of human LTA4H hydrolysis assessed as inhibition of Ca2+ ionophore-stimulated LTB4 formation in human whole blood by ELISAChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Inhibition of human recombinant LTA4H hydrolysis assessed as inhibition of LTB4 formation by LC-MS/MSChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: 33nMAssay Description:Inhibition of human LTA4H hydrolysis assessed as inhibition of Ca2+ ionophore-stimulated LTB4 formation in human whole blood by ELISAChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: 37nMAssay Description:Inhibition of human LTA4H hydrolysis assessed as inhibition of Ca2+ ionophore-stimulated LTB4 formation in human whole blood by ELISAChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: 47nMAssay Description:Inhibition of human recombinant LTA4H hydrolysis assessed as inhibition of LTB4 formation by LC-MS/MSChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: 87nMAssay Description:Inhibition of human recombinant LTA4H hydrolysis assessed as inhibition of LTB4 formation by LC-MS/MSChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: 244nMAssay Description:Inhibition of human recombinant LTA4H hydrolysis assessed as inhibition of LTB4 formation by LC-MS/MSChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: 340nMAssay Description:Inhibition of human recombinant LTA4H hydrolysis assessed as inhibition of LTB4 formation by LC-MS/MSChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: 449nMAssay Description:Inhibition of human LTA4H hydrolysis assessed as inhibition of Ca2+ ionophore-stimulated LTB4 formation in human whole blood by ELISAChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: 533nMAssay Description:Inhibition of human LTA4H hydrolysis assessed as inhibition of Ca2+ ionophore-stimulated LTB4 formation in human whole blood by ELISAChecked by AuthorMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Hebei University
Curated by ChEMBL
Hebei University
Curated by ChEMBL
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of recombinant human PTP1B expressed in Escherichia coli using p-nitrophenyl phosphate as substrate preincubated for 15 mins followed by s...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
Hebei University
Curated by ChEMBL
Hebei University
Curated by ChEMBL
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of recombinant human TCPTP expressed in Escherichia coli using p-nitrophenyl phosphate as substrate preincubated for 15 mins followed by s...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Hebei University
Curated by ChEMBL
Hebei University
Curated by ChEMBL
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of recombinant human PTP1B expressed in Escherichia coli using p-nitrophenyl phosphate as substrate preincubated for 15 mins followed by s...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
Hebei University
Curated by ChEMBL
Hebei University
Curated by ChEMBL
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of recombinant human TCPTP expressed in Escherichia coli using p-nitrophenyl phosphate as substrate preincubated for 15 mins followed by s...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2C(Rattus norvegicus (Rat))
Symphony Pharmaceuticals
Curated by ChEMBL
Symphony Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: >7.00E+3nMAssay Description:Ability of the compound to inhibit [3H]-CGS-19,755 binding to AMPA receptors.More data for this Ligand-Target Pair
Affinity DataIC50: >7.00E+3nMAssay Description:Ability of the compound to inhibit [3H]-CGS-19,755 binding to Ionotropic glutamate receptor AMPAMore data for this Ligand-Target Pair
Affinity DataIC50: 8.70E+3nMAssay Description:Inhibition of human recombinant LTA4H hydrolysis assessed as inhibition of LTB4 formation by LC-MS/MSChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Ability of the compound to inhibit [3H]-AMPA binding to Ionotropic glutamate receptor AMPAMore data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein phosphatase S(Homo sapiens (Human))
Hebei University
Curated by ChEMBL
Hebei University
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human PTPsigma expressed in Escherichia coli using p-nitrophenyl phosphate as substrate preincubated for 15 mins followed b...More data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein phosphatase S(Homo sapiens (Human))
Hebei University
Curated by ChEMBL
Hebei University
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human PTPsigma expressed in Escherichia coli using p-nitrophenyl phosphate as substrate preincubated for 15 mins followed b...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Ability of the compound to inhibit [3H]-CGS-19,755 binding to Ionotropic glutamate receptor AMPAMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Ability of the compound to inhibit [3H]-CGS-19,755 binding to Ionotropic glutamate receptor AMPAMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Ability of the compound to inhibit [3H]-AMPA binding to Ionotropic glutamate receptor AMPAMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Hebei University
Curated by ChEMBL
Hebei University
Curated by ChEMBL
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of recombinant human PTP1B expressed in Escherichia coli using p-nitrophenyl phosphate as substrate preincubated for 15 mins followed by s...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Hebei University
Curated by ChEMBL
Hebei University
Curated by ChEMBL
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of recombinant human PTP1B expressed in Escherichia coli using p-nitrophenyl phosphate as substrate preincubated for 15 mins followed by s...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Hebei University
Curated by ChEMBL
Hebei University
Curated by ChEMBL
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of recombinant human PTP1B expressed in Escherichia coli using p-nitrophenyl phosphate as substrate preincubated for 15 mins followed by s...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Hebei University
Curated by ChEMBL
Hebei University
Curated by ChEMBL
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of recombinant human PTP1B expressed in Escherichia coli using p-nitrophenyl phosphate as substrate preincubated for 15 mins followed by s...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Hebei University
Curated by ChEMBL
Hebei University
Curated by ChEMBL
Affinity DataIC50: 2.30E+4nMAssay Description:Inhibition of recombinant human PTP1B expressed in Escherichia coli using p-nitrophenyl phosphate as substrate preincubated for 15 mins followed by s...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Hebei University
Curated by ChEMBL
Hebei University
Curated by ChEMBL
Affinity DataIC50: 2.30E+4nMAssay Description:Inhibition of recombinant human PTP1B expressed in Escherichia coli using p-nitrophenyl phosphate as substrate preincubated for 15 mins followed by s...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Hebei University
Curated by ChEMBL
Hebei University
Curated by ChEMBL
Affinity DataIC50: 2.70E+4nMAssay Description:Inhibition of recombinant human PTP1B expressed in Escherichia coli using p-nitrophenyl phosphate as substrate preincubated for 15 mins followed by s...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Hebei University
Curated by ChEMBL
Hebei University
Curated by ChEMBL
Affinity DataIC50: 2.70E+4nMAssay Description:Inhibition of recombinant human PTP1B expressed in Escherichia coli using p-nitrophenyl phosphate as substrate preincubated for 15 mins followed by s...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
Hebei University
Curated by ChEMBL
Hebei University
Curated by ChEMBL
Affinity DataIC50: 3.50E+4nMAssay Description:Inhibition of recombinant human TCPTP expressed in Escherichia coli using p-nitrophenyl phosphate as substrate preincubated for 15 mins followed by s...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
Hebei University
Curated by ChEMBL
Hebei University
Curated by ChEMBL
Affinity DataIC50: 3.50E+4nMAssay Description:Inhibition of recombinant human TCPTP expressed in Escherichia coli using p-nitrophenyl phosphate as substrate preincubated for 15 mins followed by s...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
Hebei University
Curated by ChEMBL
Hebei University
Curated by ChEMBL
Affinity DataIC50: 3.70E+4nMAssay Description:Inhibition of recombinant human TCPTP expressed in Escherichia coli using p-nitrophenyl phosphate as substrate preincubated for 15 mins followed by s...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
Hebei University
Curated by ChEMBL
Hebei University
Curated by ChEMBL
Affinity DataIC50: 3.70E+4nMAssay Description:Inhibition of recombinant human TCPTP expressed in Escherichia coli using p-nitrophenyl phosphate as substrate preincubated for 15 mins followed by s...More data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein phosphatase S(Homo sapiens (Human))
Hebei University
Curated by ChEMBL
Hebei University
Curated by ChEMBL
Affinity DataIC50: 3.80E+4nMAssay Description:Inhibition of recombinant human PTPsigma expressed in Escherichia coli using p-nitrophenyl phosphate as substrate preincubated for 15 mins followed b...More data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein phosphatase S(Homo sapiens (Human))
Hebei University
Curated by ChEMBL
Hebei University
Curated by ChEMBL
Affinity DataIC50: 3.80E+4nMAssay Description:Inhibition of recombinant human PTPsigma expressed in Escherichia coli using p-nitrophenyl phosphate as substrate preincubated for 15 mins followed b...More data for this Ligand-Target Pair
Affinity DataIC50: 9.80E+4nMAssay Description:Inhibition of human recombinant LTA4H hydrolysis assessed as inhibition of LTB4 formation by LC-MS/MSChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Ability of the compound to inhibit [3H]-AMPA binding to Ionotropic glutamate receptor AMPAMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Ability of the compound to inhibit [3H]-AMPA binding to Ionotropic glutamate receptor AMPAMore data for this Ligand-Target Pair
Affinity DataIC50: 1.99E+5nMAssay Description:Inhibition of human recombinant LTA4H hydrolysis assessed as inhibition of LTB4 formation by LC-MS/MSChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: >2.00E+6nMAssay Description:Inhibition of human recombinant LTA4H hydrolysis assessed as inhibition of LTB4 formation by LC-MS/MSChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: 5.38E+6nMAssay Description:Inhibition of human recombinant LTA4H hydrolysis assessed as inhibition of LTB4 formation by LC-MS/MSChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKd: 25nMAssay Description:Binding affinity to human recombinant LTA4H by isothermal calorimetryChecked by AuthorMore data for this Ligand-Target Pair