Affinity DataKi: 1.58nMAssay Description:Displacement of [3H]granisetron from human 5-HT3AR expressed in HEK293 cells after 24 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Vu University Amsterdam
Curated by ChEMBL
Vu University Amsterdam
Curated by ChEMBL
Affinity DataKi: 2.69nMAssay Description:Displacement of [3H]-MLA from human alpha7 nAChR expressed in human SH-SY5Y cellsMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Vu University Amsterdam
Curated by ChEMBL
Vu University Amsterdam
Curated by ChEMBL
Affinity DataKi: 2.75nMAssay Description:Displacement of [3H]-MLA from human alpha7 nAChR expressed in human SH-SY5Y cellsMore data for this Ligand-Target Pair
Affinity DataKi: 6.31nMAssay Description:Displacement of [3H]histamine from human H4R receptor expressed in HEK293 cells at 10 uM after 1.5 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 12.6nMAssay Description:Displacement of [3H]granisetron from human 5-HT3AR expressed in HEK293 cells after 24 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Vu University Amsterdam
Curated by ChEMBL
Vu University Amsterdam
Curated by ChEMBL
Affinity DataKi: 13.2nMAssay Description:Displacement of [3H]-MLA from human alpha7 nAChR expressed in human SH-SY5Y cellsMore data for this Ligand-Target Pair
Affinity DataKi: 14.4nMAssay Description:Displacement of [3H]epibatidine from Lymnaea stagnalis His6-AChBP expressed in Bac-to-Bac baculovirus expression systemMore data for this Ligand-Target Pair
Affinity DataKi: 18.2nMAssay Description:Displacement of [3H]epibatidine from Lymnaea stagnalis His6-AChBP expressed in Bac-to-Bac baculovirus expression systemMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Vu University Amsterdam
Curated by ChEMBL
Vu University Amsterdam
Curated by ChEMBL
Affinity DataKi: 18.6nMAssay Description:Displacement of [3H]-MLA from human alpha7 nAChR expressed in human SH-SY5Y cellsMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Vu University Amsterdam
Curated by ChEMBL
Vu University Amsterdam
Curated by ChEMBL
Affinity DataKi: 24.6nMAssay Description:Displacement of [3H]-MLA from human alpha7 nAChR expressed in human SH-SY5Y cellsMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Vu University Amsterdam
Curated by ChEMBL
Vu University Amsterdam
Curated by ChEMBL
Affinity DataKi: 25.7nMAssay Description:Displacement of [3H]-MLA from human alpha7 nAChR expressed in human SH-SY5Y cellsMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Vu University Amsterdam
Curated by ChEMBL
Vu University Amsterdam
Curated by ChEMBL
Affinity DataKi: 28.8nMAssay Description:Displacement of [3H]-MLA from human alpha7 nAChR expressed in human SH-SY5Y cellsMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Vu University Amsterdam
Curated by ChEMBL
Vu University Amsterdam
Curated by ChEMBL
Affinity DataKi: 37.1nMAssay Description:Displacement of [3H]-MLA from human alpha7 nAChR expressed in human SH-SY5Y cellsMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Vu University Amsterdam
Curated by ChEMBL
Vu University Amsterdam
Curated by ChEMBL
Affinity DataKi: 38.9nMAssay Description:Displacement of [3H]-MLA from human alpha7 nAChR expressed in human SH-SY5Y cellsMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Vu University Amsterdam
Curated by ChEMBL
Vu University Amsterdam
Curated by ChEMBL
Affinity DataKi: 43.6nMAssay Description:Displacement of [3H]-MLA from human alpha7 nAChR expressed in human SH-SY5Y cellsMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Vu University Amsterdam
Curated by ChEMBL
Vu University Amsterdam
Curated by ChEMBL
Affinity DataKi: 43.6nMAssay Description:Displacement of [3H]-MLA from human alpha7 nAChR expressed in human SH-SY5Y cellsMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Vu University Amsterdam
Curated by ChEMBL
Vu University Amsterdam
Curated by ChEMBL
Affinity DataKi: 61.7nMAssay Description:Displacement of [3H]-MLA from human alpha7 nAChR expressed in human SH-SY5Y cellsMore data for this Ligand-Target Pair
Affinity DataKi: 61.7nMAssay Description:Displacement of [3H]epibatidine from Lymnaea stagnalis His6-AChBP expressed in Bac-to-Bac baculovirus expression systemMore data for this Ligand-Target Pair
Affinity DataKi: 63.1nMAssay Description:Displacement of [3H]histamine from human H4R receptor expressed in HEK293 cells at 10 uM after 1.5 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 79.4nMAssay Description:Binding affinity to H4R receptorMore data for this Ligand-Target Pair
Affinity DataKi: 79.4nMAssay Description:Binding affinity to H4R receptorMore data for this Ligand-Target Pair
Affinity DataKi: 89.1nMAssay Description:Displacement of [3H]epibatidine from Lymnaea stagnalis His6-AChBP expressed in Bac-to-Bac baculovirus expression systemMore data for this Ligand-Target Pair
Affinity DataKi: 100nMAssay Description:Displacement of [3H]histamine from human H4R receptor expressed in HEK293 cells at 10 uM after 1.5 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Vu University Amsterdam
Curated by ChEMBL
Vu University Amsterdam
Curated by ChEMBL
Affinity DataKi: 110nMAssay Description:Displacement of [3H]-MLA from human alpha7 nAChR expressed in human SH-SY5Y cellsMore data for this Ligand-Target Pair
Affinity DataKi: 148nMAssay Description:Displacement of [3H]epibatidine from Lymnaea stagnalis His6-AChBP expressed in Bac-to-Bac baculovirus expression systemMore data for this Ligand-Target Pair
Affinity DataKi: 200nMAssay Description:Displacement of [3H]histamine from human H4R receptor expressed in HEK293 cells at 10 uM after 1.5 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 240nMAssay Description:Displacement of [3H]epibatidine from Lymnaea stagnalis His6-AChBP expressed in Bac-to-Bac baculovirus expression systemMore data for this Ligand-Target Pair
Affinity DataKi: 251nMAssay Description:Displacement of [3H]epibatidine from Lymnaea stagnalis His6-AChBP expressed in Bac-to-Bac baculovirus expression systemMore data for this Ligand-Target Pair
Affinity DataKi: 251nMAssay Description:Displacement of [3H]granisetron from human 5-HT3AR expressed in HEK293 cells after 24 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 331nMAssay Description:Displacement of [3H]epibatidine from Lymnaea stagnalis His6-AChBP expressed in Bac-to-Bac baculovirus expression systemMore data for this Ligand-Target Pair
Affinity DataKi: 468nMAssay Description:Displacement of [3H]epibatidine from Lymnaea stagnalis His6-AChBP expressed in Bac-to-Bac baculovirus expression systemMore data for this Ligand-Target Pair
Affinity DataKi: 501nMAssay Description:Displacement of [3H]epibatidine from Lymnaea stagnalis His6-AChBP expressed in Bac-to-Bac baculovirus expression systemMore data for this Ligand-Target Pair
Affinity DataKi: 562nMAssay Description:Displacement of [3H]epibatidine from Lymnaea stagnalis His6-AChBP expressed in Bac-to-Bac baculovirus expression systemMore data for this Ligand-Target Pair
Affinity DataKi: 631nMAssay Description:Displacement of [3H]histamine from human H4R receptor expressed in SK-N-MC cells at 10 uM after 1.5 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 631nMAssay Description:Displacement of [3H]histamine from human H4R receptor expressed in HEK293 cells at 10 uM after 1.5 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 631nMAssay Description:Displacement of [3H]histamine from human H4R receptor expressed in HEK293 cells at 10 uM after 1.5 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 708nMAssay Description:Displacement of [3H]epibatidine from Lymnaea stagnalis His6-AChBP expressed in Bac-to-Bac baculovirus expression systemMore data for this Ligand-Target Pair
Affinity DataKi: 794nMAssay Description:Displacement of [3H]granisetron from human 5-HT3AR expressed in HEK293 cells after 24 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 794nMAssay Description:Displacement of [3H]histamine from human H4R receptor expressed in SK-N-MC cells at 10 uM after 1.5 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 794nMAssay Description:Displacement of [3H]granisetron from human 5-HT3AR expressed in HEK293 cells after 24 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 1.00E+3nMAssay Description:Displacement of [3H]granisetron from human 5-HT3AR expressed in HEK293 cells after 24 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Vu University Amsterdam
Curated by ChEMBL
Vu University Amsterdam
Curated by ChEMBL
Affinity DataKi: 1.02E+3nMAssay Description:Displacement of [3H]-MLA from human alpha7 nAChR expressed in human SH-SY5Y cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.26E+3nMAssay Description:Displacement of [3H]granisetron from human 5-HT3AR expressed in HEK293 cells after 24 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 1.26E+3nMAssay Description:Displacement of [3H]granisetron from human 5-HT3AR expressed in HEK293 cells after 24 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Vu University Amsterdam
Curated by ChEMBL
Vu University Amsterdam
Curated by ChEMBL
Affinity DataKi: 1.95E+3nMAssay Description:Displacement of [3H]-MLA from human alpha7 nAChR expressed in human SH-SY5Y cellsMore data for this Ligand-Target Pair
Affinity DataKi: 2.09E+3nMAssay Description:Displacement of [3H]epibatidine from Lymnaea stagnalis His6-AChBP expressed in Bac-to-Bac baculovirus expression systemMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Vu University Amsterdam
Curated by ChEMBL
Vu University Amsterdam
Curated by ChEMBL
Affinity DataKi: 2.29E+3nMAssay Description:Displacement of [3H]-MLA from human alpha7 nAChR expressed in human SH-SY5Y cellsMore data for this Ligand-Target Pair
Affinity DataKi: 3.02E+3nMAssay Description:Displacement of [3H]epibatidine from Lymnaea stagnalis His6-AChBP expressed in Bac-to-Bac baculovirus expression systemMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Vu University Amsterdam
Curated by ChEMBL
Vu University Amsterdam
Curated by ChEMBL
Affinity DataKi: 3.16E+3nMAssay Description:Displacement of [3H]-MLA from human alpha7 nAChR expressed in human SH-SY5Y cellsMore data for this Ligand-Target Pair
Affinity DataKi: 3.16E+3nMAssay Description:Displacement of [3H]epibatidine from Lymnaea stagnalis His6-AChBP expressed in Bac-to-Bac baculovirus expression systemMore data for this Ligand-Target Pair