Found 2 Enz. Inhib. hit(s) with Target = 'ATP-dependent translocase ABCB1' and Ligand = 'BDBM50572469'
Affinity DataEC50: 84nMAssay Description:Inhibition of P-gp (unknown origin) expressed in MES-SA/DX5 cells assessed as increase in reversal of resistance to paclitaxel-induced cytotoxicity b...More data for this Ligand-Target Pair
Affinity DataEC50: 8.5nMAssay Description:Inhibition of P-gp (unknown origin) expressed in MCF7 cells assessed as increase in reversal of resistance to paclitaxel-induced cytotoxicity by meas...More data for this Ligand-Target Pair