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Found 3 Enz. Inhib. hit(s) with Target = 'Bcl-2 homologous antagonist/killer' and Ligand = 'BDBM50107130'
TargetBcl-2 homologous antagonist/killer(Homo sapiens)
National University Of Ireland Galway

Curated by ChEMBL
LigandPNGBDBM50107130((Z)-2-(5-(4-bromobenzylidene)-4-oxo-2-thioxothiazo...)
Affinity DataKi:  4.40E+4nMAssay Description:Binding affinity to Mcl-1/Bak (unknown origin) assessed as inhibition constant by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetBcl-2 homologous antagonist/killer(Homo sapiens)
National University Of Ireland Galway

Curated by ChEMBL
LigandPNGBDBM50107130((Z)-2-(5-(4-bromobenzylidene)-4-oxo-2-thioxothiazo...)
Affinity DataIC50:  1.10E+5nMAssay Description:Inhibition of Mcl-1/Bak (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetBcl-2 homologous antagonist/killer(Homo sapiens)
National University Of Ireland Galway

Curated by ChEMBL
LigandPNGBDBM50107130((Z)-2-(5-(4-bromobenzylidene)-4-oxo-2-thioxothiazo...)
Affinity DataKd:  8.40E+4nMAssay Description:Binding affinity to Mcl-1/Bak (unknown origin) assessed as dissociation constant by ITC methodMore data for this Ligand-Target Pair
In DepthDetails PubMed