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Found 3 Enz. Inhib. hit(s) with Target = 'Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6' and Ligand = 'BDBM50505020'
TargetBifunctional arginine demethylase and lysyl-hydroxylase JMJD6(Homo sapiens)
Xiamen University

Curated by ChEMBL
LigandPNGBDBM50505020(CHEMBL4443954)
Affinity DataIC50:  220nMAssay Description:Inhibition of His-tagged JMJD6 (unknown origin) expressed in Escherichia coli BL21 (DE3) assessed as decrease in demethylase activity by measuring re...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional arginine demethylase and lysyl-hydroxylase JMJD6(Homo sapiens)
Xiamen University

Curated by ChEMBL
LigandPNGBDBM50505020(CHEMBL4443954)
Affinity DataIC50:  2.44E+3nMAssay Description:Inhibition of JMJD6 in human HeLa cells assessed as decrease in cell proliferation measured after 72 hrs by CellTiter 96 AQueous one solution cell pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional arginine demethylase and lysyl-hydroxylase JMJD6(Homo sapiens)
Xiamen University

Curated by ChEMBL
LigandPNGBDBM50505020(CHEMBL4443954)
Affinity DataIC50:  1.02E+4nMAssay Description:Inhibition of JMJD6 in human SMCC7721 cells assessed as decrease in cell proliferation measured after 72 hrs by CellTiter 96 AQueous one solution cel...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed