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Found 3 Enz. Inhib. hit(s) with Target = 'Cannabinoid receptor 2' and Ligand = 'BDBM50258768'
TargetCannabinoid receptor 2(MOUSE)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50258768(CHEMBL4078901)
Affinity DataIC50:  151nMAssay Description:Allosteric modulation of CB1 receptor in CD-1 mouse cerebellar membranes assessed as inhibition of CP55,940-induced [35S]GTPgammaS binding after 60 m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50258768(CHEMBL4078901)
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonist activity at human CB2 receptor expressed in CHO cells co-expressing Galpha16 assessed as inhibition of CP55,940-induced calcium mobilizati...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(MOUSE)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50258768(CHEMBL4078901)
Affinity DataEC50:  790nMAssay Description:PAM antagonist activity at CB1 receptor in CD-1 mouse cerebellar membranes assessed as increase in [3H]CP55,940 binding after 90 mins relative to con...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed