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Found 2 Enz. Inhib. hit(s) with Target = 'Chymase' and Ligand = 'BDBM50452609'
TargetChymase(Homo sapiens (Human))
Asubio Pharma

Curated by ChEMBL
LigandPNGBDBM50452609(CHEMBL4206099)
Affinity DataIC50:  8.90nMAssay Description:Inhibition of recombinant human chymase pre-incubated for 10 mins before Suc-Ala-Ala-Pro-Phe-MCA substrate addition and measured after 10 mins by flu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetChymase(Homo sapiens (Human))
Asubio Pharma

Curated by ChEMBL
LigandPNGBDBM50452609(CHEMBL4206099)
Affinity DataKon:  2.10E-8M-1s-1Assay Description:Binding affinity to recombinant human chymase assessed as dissociation constant at 12.5 to 200 nM by SPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB