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Found 2 Enz. Inhib. hit(s) with Target = 'Cytochrome P450 11B1, mitochondrial' and Ligand = 'BDBM50078618'
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50078618(CHEMBL3415173 | US9278093, 2)
Affinity DataIC50:  1.42E+3nMT: 2°CAssay Description:Compounds of the Examples 1 to 3 were assayed for V79-Human-CYP11B2 and V79-Human-CYP11B1 by modifying the protocol described in J. Steroid Biochem. ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50078618(CHEMBL3415173 | US9278093, 2)
Affinity DataIC50:  4.52E+3nMAssay Description:Inhibition of human CYP11B1 expressed in V79 MZh cells using [14C]-deoxycorticosterone substrate incubated for 6 hrs by HPTLC methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed