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Found 2 Enz. Inhib. hit(s) with Target = 'Cytochrome P450 11B1, mitochondrial' and Ligand = 'BDBM50428336'
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Temple University

Curated by ChEMBL
LigandPNGBDBM50428336(CHEMBL2331704)
Affinity DataIC50:  108nMAssay Description:Inhibition of human Cyp11B1 transfected in chinese hamster V79MZ cells using deoxycorticosterone as substrate incubated for 60 mins prior to substrat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Temple University

Curated by ChEMBL
LigandPNGBDBM50428336(CHEMBL2331704)
Affinity DataIC50:  219nMAssay Description:Inhibition of human CYP11B1 expressed in V79 cells assessed as cortisol level after 3 hrs by HTRF assay in presence of 250 nM 11-deoxycortisolMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed