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Found 1 Enz. Inhib. hit(s) with Target = 'DNA topoisomerase 1' and Ligand = 'BDBM50036131'
TargetDNA topoisomerase 1(Homo sapiens (Human))
Glaxo Research Institute

Curated by ChEMBL
LigandPNGBDBM50036131(7-ethyl-7-hydroxy-14-(4-methylhexahydro-1-pyraziny...)
Affinity DataIC50:  300nMAssay Description:Inhibition of topoisomerase I activity was determined in vitro by using the cleavable complex assay(calf thymus)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed