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Found 3 Enz. Inhib. hit(s) with Target = 'Epidermal growth factor receptor' and Ligand = 'BDBM50187718'
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50187718(CHEMBL3828079)
Affinity DataIC50:  44nMAssay Description:Inhibition of cytoplasmic GST-tagged human recombinant EGFR expressed in baculovirus system by z-lyte assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50187718(CHEMBL3828079)
Affinity DataIC50:  108nMAssay Description:Inhibition of cytoplasmic GST-tagged human recombinant EGFR L858R mutant expressed in baculovirus system by z-lyte assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50187718(CHEMBL3828079)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of cytoplasmic GST-tagged human recombinant EGFR L858R/T790M double mutant (668-1210 residues) expressed in baculovirus system by z-lyte a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed