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Found 2 Enz. Inhib. hit(s) with Target = 'Farnesyl pyrophosphate synthase' and Ligand = 'BDBM50273716'
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Universita Di Ferrara

Curated by ChEMBL
LigandPNGBDBM50273716(CHEMBL457423 | [2-(Benzoimidazol-1-yl)ethyl]-bisph...)
Affinity DataIC50:  16.1nMAssay Description:Inhibition of human FPP synthase expressed in Escherichia coli BL21 (DE3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Universita Di Ferrara

Curated by ChEMBL
LigandPNGBDBM50273716(CHEMBL457423 | [2-(Benzoimidazol-1-yl)ethyl]-bisph...)
Affinity DataIC50:  24nMAssay Description:Inhibition of FDPS (unknown origin) using [14C] IPP and GPP as substrate preincubated for 10 mins followed by substrate addition and measured after 3...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed