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Found 1 Enz. Inhib. hit(s) with Target = 'GTPase KRas' and Ligand = 'BDBM629369'
TargetGTPase KRas(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM629369(US20230339981, Example 53 | US20240025919, Compoun...)
Affinity DataIC50:  0.296nMAssay Description:Biochemical compound potencies are assessed by evaluating inhibition of SOS1-mediated nucleotide exchange in KRAS WT. In this assay, the SOS1-promote...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent