Compile Data Set for Download or QSAR
maximum 50k data
Found 3 Enz. Inhib. hit(s) with Target = 'Glutaminyl-peptide cyclotransferase' and Ligand = 'BDBM7882'
TargetGlutaminyl-peptide cyclotransferase(Homo sapiens (Human))
Probiodrug

LigandPNGBDBM7882(1H-imidazole | CHEMBL540 | Imidazole (Im) | US9138...)
Affinity DataKi:  1.00E+5nM ΔG°:  -23.2kJ/molepH: 8.0 T: 2°CAssay Description:QC activity was evaluated fluorometrically using Gln-AMC as substrate, and pyroglutamyl peptidase as the auxiliary enzyme. After conversion of Gln-AM...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutaminyl-peptide cyclotransferase(Mus musculus (mouse))
Probiodrug

LigandPNGBDBM7882(1H-imidazole | CHEMBL540 | Imidazole (Im) | US9138...)
Affinity DataKi:  1.60E+5nM ΔG°:  -22.0kJ/molepH: 8.0 T: 2°CAssay Description:QC activity was evaluated fluorometrically using Gln-AMC as substrate, and pyroglutamyl peptidase as the auxiliary enzyme. After conversion of Gln-AM...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutaminyl-peptide cyclotransferase(Homo sapiens (Human))
Probiodrug

LigandPNGBDBM7882(1H-imidazole | CHEMBL540 | Imidazole (Im) | US9138...)
Affinity DataIC50:  3.52E+5nMAssay Description:Inhibition of recombinant human QC using H-Gln-AMC hydrobromide as fluorogenic substrate incubated for 6 hrs by fluorometric microplate reader analys...More data for this Ligand-Target Pair
In DepthDetails PubMed