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Found 3 Enz. Inhib. hit(s) with Target = 'Kinesin-like protein KIF11' and Ligand = 'BDBM50351254'
TargetKinesin-like protein KIF11(Homo sapiens (Human))
The Beatson Institute For Cancer Research

Curated by ChEMBL
LigandPNGBDBM50351254(CHEMBL1818529)
Affinity DataKi:  22nMAssay Description:Inhibition of human N-terminal His6-tagged Eg5 (1 to 368 amino acid residues) motor domain basal ATPase activity expressed in Escherichia coli BL21 (...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
The Beatson Institute For Cancer Research

Curated by ChEMBL
LigandPNGBDBM50351254(CHEMBL1818529)
Affinity DataIC50:  136nMAssay Description:Inhibition of human recombinant microtubule-activated KSP motor domain ATPase activity after 10 mins by end-point assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
The Beatson Institute For Cancer Research

Curated by ChEMBL
LigandPNGBDBM50351254(CHEMBL1818529)
Affinity DataEC50:  115nMAssay Description:Inhibition of KSP in human HeLa cells assessed as bipolar spindle formationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed