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Found 4 Enz. Inhib. hit(s) with Target = 'Macrophage migration inhibitory factor' and Ligand = 'BDBM50547499'
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
L2 Diagnostics

Curated by ChEMBL
LigandPNGBDBM50547499(CHEMBL4785454)
Affinity DataIC50:  930nMAssay Description:Inhibition of recombinant human MIF expressed in Escherichia coli BL21 DE3 binding to recombinant soluble human CD74 receptor ectodomain (73 to 232 r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
L2 Diagnostics

Curated by ChEMBL
LigandPNGBDBM50547499(CHEMBL4785454)
Affinity DataIC50:  4.42E+3nMAssay Description:Inhibition of MIF-induced IL-8 secretion in human foreskin fibroblasts incubated for 30 mins by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
L2 Diagnostics

Curated by ChEMBL
LigandPNGBDBM50547499(CHEMBL4785454)
Affinity DataIC50:  7.59E+3nMAssay Description:Inhibition of recombinant biotinylated human MIF tautomerase activity expressed in Escherichia coli BL21 DE3 assessed as reduction in tautomerization...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
L2 Diagnostics

Curated by ChEMBL
LigandPNGBDBM50547499(CHEMBL4785454)
Affinity DataKd:  6.86E+3nMAssay Description:Binding affinity to recombinant biotinylated human MIF expressed in Escherichia coli BL21 DE3 by surface plasmon resonance assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB