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Found 10 Enz. Inhib. hit(s) with Target = 'Neuropeptide FF receptor 2' and Ligand = 'BDBM50037557'
TargetNeuropeptide FF receptor 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50037557(2-{[1-(2-{2-[2-(2-Amino-3-phenyl-propionylamino)-4...)
Affinity DataKi:  0.0200nMAssay Description:Displacement of [125I]-1DMeNPFF from recombinant human NPFF2 receptor expressed in CHO cells by TopCount scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide FF receptor 2(RAT)
Cnrs

Curated by ChEMBL
LigandPNGBDBM50037557(2-{[1-(2-{2-[2-(2-Amino-3-phenyl-propionylamino)-4...)
Affinity DataKi:  0.210nMAssay Description:Binding affinity for NPPF receptor in rat spinal cord membranes using the radioligand [125I]-[Tyr1]NPFFMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide FF receptor 2(Mus musculus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50037557(2-{[1-(2-{2-[2-(2-Amino-3-phenyl-propionylamino)-4...)
Affinity DataKi:  1.10nMAssay Description:Displacement of [125I]-1DMeNPFF from mouse NPFF2R receptor by TopCount scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide FF receptor 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50037557(2-{[1-(2-{2-[2-(2-Amino-3-phenyl-propionylamino)-4...)
Affinity DataKi:  1.20nMAssay Description:Displacement of [3H]EYE from human NPFF2 receptor expressed in CHO cell membranes after 1 hr by liquid scintillation spectrophotometric countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide FF receptor 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50037557(2-{[1-(2-{2-[2-(2-Amino-3-phenyl-propionylamino)-4...)
Affinity DataEC50:  43nMAssay Description:Agonist activity at NPFF2R (unknown origin) expressed in HEK293-A cells assessed as inhibition of forskolin-induced cAMP accumulation preincubated fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide FF receptor 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50037557(2-{[1-(2-{2-[2-(2-Amino-3-phenyl-propionylamino)-4...)
Affinity DataKd:  0.210nMAssay Description:Binding affinity to human NPFFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide FF receptor 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50037557(2-{[1-(2-{2-[2-(2-Amino-3-phenyl-propionylamino)-4...)
Affinity DataEC50:  42nMAssay Description:Agonist activity at NPFF2R (unknown origin) expressed in HEK293-A cells assessed as inhibition of forskolin-induced cAMP accumulation preincubated fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide FF receptor 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50037557(2-{[1-(2-{2-[2-(2-Amino-3-phenyl-propionylamino)-4...)
Affinity DataKd:  0.370nMAssay Description:Binding affinity to human NPFFR2 expressed in green monkey COS-7 cell membranes by [125I]-1DMeNPFF radioligand based saturation binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide FF receptor 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50037557(2-{[1-(2-{2-[2-(2-Amino-3-phenyl-propionylamino)-4...)
Affinity DataEC50:  40nMAssay Description:Agonist activity at NPFF2 receptor (unknown origin) expressed in HEK293A cells assessed as inhibition of forskolin-stimulated cAMP accumulation measu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide FF receptor 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50037557(2-{[1-(2-{2-[2-(2-Amino-3-phenyl-propionylamino)-4...)
Affinity DataEC50:  3.20nMAssay Description:Agonist activity at human NPFFR2 expressed in CHO cells assessed as inhibition of forskolin-induced intracellular cyclic cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed