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Found 2 Enz. Inhib. hit(s) with Target = 'Phospholipid hydroperoxide glutathione peroxidase' and Ligand = 'BDBM66431'
TargetPhospholipid hydroperoxide glutathione peroxidase(Homo sapiens)
Institute Of Mit And Harvard

Curated by ChEMBL
LigandPNGBDBM66431(2-(3-chloro-N-(2-chloro-1-oxoethyl)-4-methoxyanili...)
Affinity DataEC50:  2.20E+3nMAssay Description:Inhibition of GPX4 in human LOX IMVI cells assessed as ferroptosis-mediated cell death measured as cell viability in presence of ferrostatin-1More data for this Ligand-Target Pair
TargetPhospholipid hydroperoxide glutathione peroxidase(Homo sapiens)
Institute Of Mit And Harvard

Curated by ChEMBL
LigandPNGBDBM66431(2-(3-chloro-N-(2-chloro-1-oxoethyl)-4-methoxyanili...)
Affinity DataEC50:  28nMAssay Description:Inhibition of GPX4 in human LOX IMVI cells assessed as ferroptosis-mediated cell death measured as cell viabilityMore data for this Ligand-Target Pair