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Found 3 Enz. Inhib. hit(s) with Target = 'Poly [ADP-ribose] polymerase 1' and Ligand = 'BDBM50300017'
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50300017(2-(biphenyl-4-yl)-1H-benzo[d]imidazole-4-carboxami...)
Affinity DataKi:  2nMAssay Description:Inhibition of PARP1 by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50300017(2-(biphenyl-4-yl)-1H-benzo[d]imidazole-4-carboxami...)
Affinity DataIC50:  710nMAssay Description:Inhibition of PARP-1 (unknown origin) assessed as incorporation of biotinylated poly (ADP-ribose) onto histone protein after 60 mins by TACS-Sapphire...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50300017(2-(biphenyl-4-yl)-1H-benzo[d]imidazole-4-carboxami...)
Affinity DataEC50:  71nMAssay Description:Inhibition of PARP1 in human C41 cells after 30 mins by cell-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed