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Found 5 Enz. Inhib. hit(s) with Target = 'Protein polybromo-1' and Ligand = 'BDBM50158688'
TargetProtein polybromo-1(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50158688(CHEMBL3752911)
Affinity DataKd:  48nMAssay Description:Binding affinity to PB1 bromodomain5 (unknown origin) by isothermal titration calorimetric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein polybromo-1(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50158688(CHEMBL3752911)
Affinity DataKd: <100nMAssay Description:Binding affinity to human PB1 isoform 5 expressed in BL21 (DE3)-R3-BirA cells by isothermal titration calorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein polybromo-1(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50158688(CHEMBL3752911)
Affinity DataKd:  5.80E+3nMAssay Description:Binding affinity to human PBRM1 bromodomain 2 (S178 to E291 residues) expressed in bacterial expression system by bromoscan assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetProtein polybromo-1(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50158688(CHEMBL3752911)
Affinity DataKd:  25nMAssay Description:Binding affinity to human PBRM1 bromodomain 5 (S645 to D766 residues) expressed in bacterial expression system by bromoscan assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetProtein polybromo-1(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50158688(CHEMBL3752911)
Affinity DataKd:  48nMAssay Description:Binding affinity to His6-tagged human recombinant PB1 bromodomain isoform 5 expressed in Escherichia coli BL21(DE3)-R3-pRARE2 cells by VP-ITC microca...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed