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Found 3 Enz. Inhib. hit(s) with Target = 'Renin' and Ligand = 'BDBM98686'
TargetRenin(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM98686(US8497286, 162)
Affinity DataIC50:  0.300nMAssay Description:Inhibition activity of renin using FRET assay.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRenin(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM98686(US8497286, 162)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of human recombinant renin using fluorescence-quenched RE(EDANS)IHPFHLVIHTK(Dabcyl)R substrate by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM98686(US8497286, 162)
Affinity DataIC50:  2.5nMAssay Description:Inhibition of human recombinant renin in presence of human plasma using Ac- IHPFHL-VIHNK-(DY-505-X5)-COOH substrate by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed