Found 6 Enz. Inhib. hit(s) with Target = 'Sodium- and chloride-dependent glycine transporter 1' and Ligand = 'BDBM50149871' TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Nagasaki University
Curated by ChEMBL
Nagasaki University
Curated by ChEMBL
Affinity DataIC50: 0.390nMAssay Description:Inhibition of GlyT1 in human JAR cells assessed as inhibition of [3H]glycine uptake preincubated for 1 mins measured after 2 hrs by liquid scintillat...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Nagasaki University
Curated by ChEMBL
Nagasaki University
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of human GlyT1 expressed in QT6 cells assessed as reduction in [14C]glycine uptake incubated for 20 mins by liquid scintillation counting ...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Nagasaki University
Curated by ChEMBL
Nagasaki University
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of human GlyT-1More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(attus norvegicus (Rat))
Astellas Pharma
Curated by ChEMBL
Astellas Pharma
Curated by ChEMBL
Affinity DataIC50: 8.90nMAssay Description:Displacement of [3H]glycine from GlyT1 in rat C6 glioma cells incubated for 30 mins prior to substrate addition measured after 10 mins by scintillati...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Nagasaki University
Curated by ChEMBL
Nagasaki University
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Inhibition of human GlyT1 expressed in porcine aorta epithelial cells assessed as reduction in [3H]-Glycine uptake incubated for 10 mins at pH 7.4 by...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Nagasaki University
Curated by ChEMBL
Nagasaki University
Curated by ChEMBL
Affinity DataIC50: 26nMAssay Description:Inhibition of uptake of [3H]-glycine into cells transfected with human GlyT-1b transporterChecked by AuthorMore data for this Ligand-Target Pair
