Compile Data Set for Download or QSAR
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Found 3 Enz. Inhib. hit(s) with Target = 'Sphingosine 1-phosphate receptor 1' and Ligand = 'BDBM50399039'
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50399039(CHEMBL2178814)
Affinity DataIC50:  3.40nMAssay Description:Antagonist activity at human S1P1R receptor expressed in CHO cell membranes by [35S]GTPgamma binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50399039(CHEMBL2178814)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human S1P1R receptor expressed in CHO cell membranes by [35S]GTPgamma binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50399039(CHEMBL2178814)
Affinity DataKd:  0.670nMAssay Description:Competitive binding affinity to human S1P1R receptor expressed in CHO cell membranes by Schild plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed