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Found 3 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase ABL1' and Ligand = 'BDBM120395'
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Harbin Gloria Pharmaceuticals

US Patent
LigandPNGBDBM120395(US8703771, 13 | US8703771, 14 | US8703771, 8)
Affinity DataIC50:  2.40nMpH: 7.5 T: 2°CAssay Description:The activity of the compounds of this invention on Abl, c-Kit and PDGFR kinases was tested by Mobility Shift Assay (MSA). Kinase buffer: 62.5 mM HEPE...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Harbin Gloria Pharmaceuticals

US Patent
LigandPNGBDBM120395(US8703771, 13 | US8703771, 14 | US8703771, 8)
Affinity DataIC50:  5.30nMpH: 7.5 T: 2°CAssay Description:The activity of the compounds of this invention on Abl, c-Kit and PDGFR kinases was tested by Mobility Shift Assay (MSA). Kinase buffer: 62.5 mM HEPE...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Harbin Gloria Pharmaceuticals

US Patent
LigandPNGBDBM120395(US8703771, 13 | US8703771, 14 | US8703771, 8)
Affinity DataIC50:  266nMpH: 7.5 T: 2°CAssay Description:The activity of the compounds of this invention on Abl, c-Kit and PDGFR kinases was tested by Mobility Shift Assay (MSA). Kinase buffer: 62.5 mM HEPE...More data for this Ligand-Target Pair
In DepthDetails US Patent