TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Janssen Research & Development
Curated by ChEMBL
Janssen Research & Development
Curated by ChEMBL
Affinity DataKi: 337nMAssay Description:Covalent inhibition of recombinant human GST-tagged BTK (2 to 659 end residues) expressed in baculovirus expression system assessed as inhibition con...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Janssen Research & Development
Curated by ChEMBL
Janssen Research & Development
Curated by ChEMBL
Affinity DataIC50: 42nMAssay Description:Inhibition of BTK in C57Bl/6 mouse splenocyte assessed as reduction in anti-IgM-induced CD69 expression incubated for 1 hr followed anti-IgM stimulat...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Janssen Research & Development
Curated by ChEMBL
Janssen Research & Development
Curated by ChEMBL