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Found 2 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK1' and Ligand = 'BDBM147735'
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM147735(US8962608, 28-47)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of GST-tagged recombinant human JAK1 catalytic domain expressed in baculovirus expression system using LCB-EQEDEPEGDYFEWLW-NH2 as substrat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM147735(US8962608, 28-47)
Affinity DataIC50:  0.300nMAssay Description:The ability of compounds to inhibit the activity of JAK1, JAK2, JAK3, and Tyk2 was measured using a recombinant purified GST-tagged catalytic domain ...More data for this Ligand-Target Pair
In DepthDetails US Patent