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Found 2 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase SYK' and Ligand = 'BDBM50276015'
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50276015(CHEMBL509161 | N-(3,5-dimethylphenyl)-4-(thiazol-2...)
Affinity DataKi:  8nMAssay Description:Inhibition of SYK (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50276015(CHEMBL509161 | N-(3,5-dimethylphenyl)-4-(thiazol-2...)
Affinity DataIC50:  550nMAssay Description:Inhibition of SYK (unknown origin)-mediated FCepsilonRI signaling activity by mast cell degranulation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed