Found 4 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase receptor UFO' and Ligand = 'BDBM50382425' TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
Hunan Normal University
Curated by ChEMBL
Hunan Normal University
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Inhibition of human Axl using KKSRGDYMTMQIG as substrate incubated for 40 mins in the presence of [gamma33P]ATP by scintillation counting analysisMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
Hunan Normal University
Curated by ChEMBL
Hunan Normal University
Curated by ChEMBL
Affinity DataIC50: 27nMAssay Description:Inhibition of human recombinant His-tagged AXL kinase using fluorescein-labelled poly-GT as substrate after 60 mins by TR-FRET analysisMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
Hunan Normal University
Curated by ChEMBL
Hunan Normal University
Curated by ChEMBL
Affinity DataEC50: 305nMAssay Description:Inhibition of AXL-mediated AKT Ser473 phosphorylation in human PSN1 cells assessed as decrease in GAS6-induced phospho-AKT level after 2 hrs by ELISAMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
Hunan Normal University
Curated by ChEMBL
Hunan Normal University
Curated by ChEMBL
Affinity DataEC50: 222nMAssay Description:Inhibition of AXL in human PSN1 cells assessed as decrease in GAS6-induced phospho-AXL level after 2 hrs by EILSAMore data for this Ligand-Target Pair
