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Found 3 Enz. Inhib. hit(s) with Target = 'Vasopressin V2 receptor' and Ligand = 'BDBM50125101'
TargetVasopressin V2 receptor(Rattus norvegicus (Rat))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50125101(Biphenyl-2-carboxylic acid [4-(1,3,4,5-tetrahydro-...)
Affinity DataIC50:  1nMAssay Description:Binding affinity towards V2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50125101(Biphenyl-2-carboxylic acid [4-(1,3,4,5-tetrahydro-...)
Affinity DataIC50:  20nMAssay Description:Displacement of [3H]-AVP from human V2 receptors expressed in HEK-293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50125101(Biphenyl-2-carboxylic acid [4-(1,3,4,5-tetrahydro-...)
Affinity DataIC50:  70nMAssay Description:Inhibitory activity of the human V2 receptor was assessed by the accumulation of cAMP in transfected HEK-293 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed