TargetGenome polyprotein(Hepatitis C virus (HCV genotype 1a, isolate H))
University of Massachusetts Medical School
University of Massachusetts Medical School
Affinity DataIC50: 0.230nMAssay Description:NS3/4A protease was preincubated with increasing concentration of drugs in protease reaction buffer for 1 hour. Inhibition assays were performed in ...More data for this Ligand-Target Pair
TargetGenome polyprotein(Hepatitis C virus (HCV genotype 1a, isolate H))
University of Massachusetts Medical School
University of Massachusetts Medical School
Affinity DataIC50: 0.240nMAssay Description:NS3/4A protease was preincubated with increasing concentration of drugs in protease reaction buffer for 1 hour. Inhibition assays were performed in ...More data for this Ligand-Target Pair
TargetGenome polyprotein(Hepatitis C virus (HCV genotype 1a, isolate H))
University of Massachusetts Medical School
University of Massachusetts Medical School
Affinity DataIC50: 0.260nMAssay Description:NS3/4A protease was preincubated with increasing concentration of drugs in protease reaction buffer for 1 hour. Inhibition assays were performed in ...More data for this Ligand-Target Pair
TargetGenome polyprotein(Hepatitis C virus (HCV genotype 1a, isolate H))
University of Massachusetts Medical School
University of Massachusetts Medical School
Affinity DataIC50: 0.290nMAssay Description:NS3/4A protease was preincubated with increasing concentration of drugs in protease reaction buffer for 1 hour. Inhibition assays were performed in ...More data for this Ligand-Target Pair
TargetGenome polyprotein(Hepatitis C virus (HCV genotype 1a, isolate H))
University of Massachusetts Medical School
University of Massachusetts Medical School
Affinity DataIC50: <0.300nMAssay Description:The inhibitory activity of certain compounds of Table A against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length ...More data for this Ligand-Target Pair
TargetGenome polyprotein(Hepatitis C virus (HCV genotype 1a, isolate H))
University of Massachusetts Medical School
University of Massachusetts Medical School
Affinity DataIC50: 0.5nMAssay Description:The inhibitory activity of certain compounds of Table A against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length ...More data for this Ligand-Target Pair
TargetGenome polyprotein(Hepatitis C virus (HCV genotype 1a, isolate H))
University of Massachusetts Medical School
University of Massachusetts Medical School
Affinity DataIC50: 0.600nMAssay Description:Measurement of inhibition by compounds was performed using the HCV replicon system. Several different replicons encoding different HCV genotypes or m...More data for this Ligand-Target Pair
TargetGenome polyprotein(Hepatitis C virus (HCV genotype 1a, isolate H))
University of Massachusetts Medical School
University of Massachusetts Medical School
Affinity DataIC50: 0.600nMAssay Description:Measurement of inhibition by compounds was performed using the HCV replicon system. Several different replicons encoding different HCV genotypes or m...More data for this Ligand-Target Pair
TargetGenome polyprotein(Hepatitis C virus (HCV genotype 1a, isolate H))
University of Massachusetts Medical School
University of Massachusetts Medical School
Affinity DataIC50: 0.600nMAssay Description:The inhibitory activity of certain compounds of Table A against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length ...More data for this Ligand-Target Pair
TargetGenome polyprotein(Hepatitis C virus (HCV genotype 1a, isolate H))
University of Massachusetts Medical School
University of Massachusetts Medical School
Affinity DataIC50: 0.600nMAssay Description:The inhibitory activity of certain compounds of Table A against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length ...More data for this Ligand-Target Pair
TargetGenome polyprotein(Hepatitis C virus (HCV genotype 1a, isolate H))
University of Massachusetts Medical School
University of Massachusetts Medical School
Affinity DataIC50: 0.700nMAssay Description:Measurement of inhibition by compounds was performed using the HCV replicon system. Several different replicons encoding different HCV genotypes or m...More data for this Ligand-Target Pair
TargetGenome polyprotein(Hepatitis C virus (HCV genotype 1a, isolate H))
University of Massachusetts Medical School
University of Massachusetts Medical School
Affinity DataIC50: 0.800nMAssay Description:The inhibitory activity of certain compounds of Table A against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length ...More data for this Ligand-Target Pair
TargetGenome polyprotein(Hepatitis C virus (HCV genotype 1a, isolate H))
University of Massachusetts Medical School
University of Massachusetts Medical School
Affinity DataIC50: 0.900nMAssay Description:The inhibitory activity of certain compounds of Table A against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length ...More data for this Ligand-Target Pair
TargetGenome polyprotein(Hepatitis C virus (HCV genotype 1a, isolate H))
University of Massachusetts Medical School
University of Massachusetts Medical School
Affinity DataIC50: 0.900nMAssay Description:The inhibitory activity of certain compounds of Table A against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length ...More data for this Ligand-Target Pair
TargetGenome polyprotein(Hepatitis C virus (HCV genotype 1a, isolate H))
University of Massachusetts Medical School
University of Massachusetts Medical School
Affinity DataIC50: 0.900nMAssay Description:The inhibitory activity of certain compounds of Table A against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length ...More data for this Ligand-Target Pair
TargetGenome polyprotein(Hepatitis C virus (HCV genotype 1a, isolate H))
University of Massachusetts Medical School
University of Massachusetts Medical School
Affinity DataIC50: 0.900nMAssay Description:Measurement of inhibition by compounds was performed using the HCV replicon system. Several different replicons encoding different HCV genotypes or m...More data for this Ligand-Target Pair
TargetGenome polyprotein(Hepatitis C virus (HCV genotype 1a, isolate H))
University of Massachusetts Medical School
University of Massachusetts Medical School
Affinity DataIC50: 0.900nMAssay Description:Measurement of inhibition by compounds was performed using the HCV replicon system. Several different replicons encoding different HCV genotypes or m...More data for this Ligand-Target Pair
TargetGenome polyprotein(Hepatitis C virus (HCV genotype 1a, isolate H))
University of Massachusetts Medical School
University of Massachusetts Medical School
Affinity DataIC50: 0.900nMAssay Description:The inhibitory activity of certain compounds of Table A against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length ...More data for this Ligand-Target Pair
TargetGenome polyprotein(Hepatitis C virus (HCV genotype 1a, isolate H))
University of Massachusetts Medical School
University of Massachusetts Medical School
Affinity DataIC50: 0.971nMAssay Description:To initiate an assay, replicon cells were plated in the presence of a dilution series of test compound in the absence of G418. Typically, the assays ...More data for this Ligand-Target Pair
TargetGenome polyprotein(Hepatitis C virus (HCV genotype 1a, isolate H))
University of Massachusetts Medical School
University of Massachusetts Medical School
Affinity DataIC50: 1nMAssay Description:Measurement of inhibition by compounds was performed using the HCV replicon system. Several different replicons encoding different HCV genotypes or m...More data for this Ligand-Target Pair
TargetGenome polyprotein(Hepatitis C virus (HCV genotype 1a, isolate H))
University of Massachusetts Medical School
University of Massachusetts Medical School
Affinity DataIC50: 1nMAssay Description:Measurement of inhibition by compounds was performed using the HCV replicon system. Several different replicons encoding different HCV genotypes or m...More data for this Ligand-Target Pair
TargetGenome polyprotein(Hepatitis C virus (HCV genotype 1a, isolate H))
University of Massachusetts Medical School
University of Massachusetts Medical School
Affinity DataIC50: 1nMAssay Description:The inhibitory activity of certain compounds of Table A against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length ...More data for this Ligand-Target Pair
TargetGenome polyprotein(Hepatitis C virus (HCV genotype 1a, isolate H))
University of Massachusetts Medical School
University of Massachusetts Medical School
Affinity DataIC50: 1nMAssay Description:Measurement of inhibition by compounds was performed using the HCV replicon system. Several different replicons encoding different HCV genotypes or m...More data for this Ligand-Target Pair
TargetGenome polyprotein(Hepatitis C virus (HCV genotype 1a, isolate H))
University of Massachusetts Medical School
University of Massachusetts Medical School
Affinity DataIC50: 1nMAssay Description:The inhibitory activity of certain compounds of Table A against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length ...More data for this Ligand-Target Pair
TargetGenome polyprotein(Hepatitis C virus (HCV genotype 1a, isolate H))
University of Massachusetts Medical School
University of Massachusetts Medical School
Affinity DataIC50: 1nMAssay Description:The inhibitory activity of certain compounds of Table A against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length ...More data for this Ligand-Target Pair
TargetGenome polyprotein(Hepatitis C virus (HCV genotype 1a, isolate H))
University of Massachusetts Medical School
University of Massachusetts Medical School
Affinity DataIC50: 1nMAssay Description:The inhibitory activity of certain compounds of Table A against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length ...More data for this Ligand-Target Pair
TargetGenome polyprotein(Hepatitis C virus (HCV genotype 1a, isolate H))
University of Massachusetts Medical School
University of Massachusetts Medical School
Affinity DataIC50: 1nMAssay Description:The inhibitory activity of certain compounds of Table A against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length ...More data for this Ligand-Target Pair
TargetGenome polyprotein(Hepatitis C virus (HCV genotype 1a, isolate H))
University of Massachusetts Medical School
University of Massachusetts Medical School
Affinity DataIC50: 1.10nMAssay Description:The inhibitory activity of certain compounds of Table A against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length ...More data for this Ligand-Target Pair
TargetGenome polyprotein(Hepatitis C virus (HCV genotype 1a, isolate H))
University of Massachusetts Medical School
University of Massachusetts Medical School
Affinity DataIC50: 1.10nMAssay Description:Measurement of inhibition by compounds was performed using the HCV replicon system. Several different replicons encoding different HCV genotypes or m...More data for this Ligand-Target Pair
TargetGenome polyprotein(Hepatitis C virus (HCV genotype 1a, isolate H))
University of Massachusetts Medical School
University of Massachusetts Medical School
Affinity DataIC50: 1.10nMAssay Description:Measurement of inhibition by compounds was performed using the HCV replicon system. Several different replicons encoding different HCV genotypes or m...More data for this Ligand-Target Pair
TargetGenome polyprotein(Hepatitis C virus (HCV genotype 1a, isolate H))
University of Massachusetts Medical School
University of Massachusetts Medical School
Affinity DataIC50: 1.10nMAssay Description:Measurement of inhibition by compounds was performed using the HCV replicon system. Several different replicons encoding different HCV genotypes or m...More data for this Ligand-Target Pair
TargetGenome polyprotein(Hepatitis C virus (HCV genotype 1a, isolate H))
University of Massachusetts Medical School
University of Massachusetts Medical School
Affinity DataIC50: 1.10nMAssay Description:Measurement of inhibition by compounds was performed using the HCV replicon system. Several different replicons encoding different HCV genotypes or m...More data for this Ligand-Target Pair
TargetGenome polyprotein(Hepatitis C virus (HCV genotype 1a, isolate H))
University of Massachusetts Medical School
University of Massachusetts Medical School
Affinity DataIC50: 1.15nMAssay Description:To initiate an assay, replicon cells were plated in the presence of a dilution series of test compound in the absence of G418. Typically, the assays ...More data for this Ligand-Target Pair
TargetGenome polyprotein(Hepatitis C virus (HCV genotype 1a, isolate H))
University of Massachusetts Medical School
University of Massachusetts Medical School
Affinity DataIC50: 1.20nMAssay Description:Measurement of inhibition by compounds was performed using the HCV replicon system. Several different replicons encoding different HCV genotypes or m...More data for this Ligand-Target Pair
TargetGenome polyprotein(Hepatitis C virus (HCV genotype 1a, isolate H))
University of Massachusetts Medical School
University of Massachusetts Medical School
Affinity DataIC50: 1.20nMAssay Description:Measurement of inhibition by compounds was performed using the HCV replicon system. Several different replicons encoding different HCV genotypes or m...More data for this Ligand-Target Pair
TargetGenome polyprotein(Hepatitis C virus (HCV genotype 1a, isolate H))
University of Massachusetts Medical School
University of Massachusetts Medical School
Affinity DataIC50: 1.20nMAssay Description:The inhibitory activity of certain compounds of Table A against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length ...More data for this Ligand-Target Pair
TargetGenome polyprotein(Hepatitis C virus (HCV genotype 1a, isolate H))
University of Massachusetts Medical School
University of Massachusetts Medical School
Affinity DataIC50: 1.30nMAssay Description:The inhibitory activity of certain compounds of Table A against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length ...More data for this Ligand-Target Pair
TargetGenome polyprotein(Hepatitis C virus (HCV genotype 1a, isolate H))
University of Massachusetts Medical School
University of Massachusetts Medical School
Affinity DataIC50: 1.30nMAssay Description:Measurement of inhibition by compounds was performed using the HCV replicon system. Several different replicons encoding different HCV genotypes or m...More data for this Ligand-Target Pair
TargetGenome polyprotein(Hepatitis C virus (HCV genotype 1a, isolate H))
University of Massachusetts Medical School
University of Massachusetts Medical School
Affinity DataIC50: 1.40nMAssay Description:Measurement of inhibition by compounds was performed using the HCV replicon system. Several different replicons encoding different HCV genotypes or m...More data for this Ligand-Target Pair
TargetGenome polyprotein(Hepatitis C virus (HCV genotype 1a, isolate H))
University of Massachusetts Medical School
University of Massachusetts Medical School
Affinity DataIC50: 1.40nMAssay Description:The inhibitory activity of certain compounds of Table A against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length ...More data for this Ligand-Target Pair
TargetGenome polyprotein(Hepatitis C virus (HCV genotype 1a, isolate H))
University of Massachusetts Medical School
University of Massachusetts Medical School
Affinity DataIC50: 1.40nMAssay Description:The inhibitory activity of certain compounds of Table A against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length ...More data for this Ligand-Target Pair
TargetGenome polyprotein(Hepatitis C virus (HCV genotype 1a, isolate H))
University of Massachusetts Medical School
University of Massachusetts Medical School
Affinity DataIC50: 1.40nMAssay Description:The inhibitory activity of certain compounds of Table A against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length ...More data for this Ligand-Target Pair
TargetGenome polyprotein(Hepatitis C virus (HCV genotype 1a, isolate H))
University of Massachusetts Medical School
University of Massachusetts Medical School
Affinity DataIC50: 1.40nMAssay Description:Measurement of inhibition by compounds was performed using the HCV replicon system. Several different replicons encoding different HCV genotypes or m...More data for this Ligand-Target Pair
TargetGenome polyprotein(Hepatitis C virus (HCV genotype 1a, isolate H))
University of Massachusetts Medical School
University of Massachusetts Medical School
Affinity DataIC50: 1.40nMAssay Description:The inhibitory activity of certain compounds of Table A against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length ...More data for this Ligand-Target Pair
TargetGenome polyprotein(Hepatitis C virus (HCV genotype 1a, isolate H))
University of Massachusetts Medical School
University of Massachusetts Medical School
Affinity DataIC50: 1.49nMAssay Description:To initiate an assay, replicon cells were plated in the presence of a dilution series of test compound in the absence of G418. Typically, the assays ...More data for this Ligand-Target Pair
TargetGenome polyprotein(Hepatitis C virus (HCV genotype 1a, isolate H))
University of Massachusetts Medical School
University of Massachusetts Medical School
Affinity DataIC50: 1.5nMAssay Description:The inhibitory activity of certain compounds of Table A against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length ...More data for this Ligand-Target Pair
TargetGenome polyprotein(Hepatitis C virus (HCV genotype 1a, isolate H))
University of Massachusetts Medical School
University of Massachusetts Medical School
Affinity DataIC50: 1.5nMAssay Description:The inhibitory activity of certain compounds of Table A against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length ...More data for this Ligand-Target Pair
TargetGenome polyprotein(Hepatitis C virus (HCV genotype 1a, isolate H))
University of Massachusetts Medical School
University of Massachusetts Medical School
Affinity DataIC50: 1.5nMAssay Description:The inhibitory activity of certain compounds of Table A against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length ...More data for this Ligand-Target Pair
TargetGenome polyprotein(Hepatitis C virus (HCV genotype 1a, isolate H))
University of Massachusetts Medical School
University of Massachusetts Medical School
Affinity DataIC50: 1.5nMAssay Description:Measurement of inhibition by compounds was performed using the HCV replicon system. Several different replicons encoding different HCV genotypes or m...More data for this Ligand-Target Pair
TargetGenome polyprotein(Hepatitis C virus (HCV genotype 1a, isolate H))
University of Massachusetts Medical School
University of Massachusetts Medical School
Affinity DataIC50: 1.5nMAssay Description:The inhibitory activity of certain compounds of Table A against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length ...More data for this Ligand-Target Pair